Analysing the Effectiveness of University Scientific Research Projects on the Knowledge Management

This paper briefly analyzes the connotation and characteristic of knowledge management. Elaborating the problems which exist in the present scientific research project management, analyzing the relationship between university scientific research project management and knowledge management; putting forward the knowledgeable, informatization, modernization and humanization strategy into the process of scientific research project management under the view of knowledge management, and exploring theory and method to make full use of knowledge management, establishing the comprehensive and whole process management mechanism in local university scientific research project management, so as to improve the efficiency of scientific research project management, promoting the development of local colleges and universities’ scientific research

Characteristics of University’s Scientific Research Project Management i n the New Times

Along with the comprehensive deepening of reform and open, China\u27s economic has developed rapidly. National and provincial’s longitudinal and transverse scientific research projects are increasing. In particular, our country has many universities and they have close relationship with economics’ development. Also, scientific research projects that involved are multitude of names. Understand our country’s characteristics of scientific research project i n the new period correctly. Adjust local university’s scientific research project management method, means and key in time, and make out corresponding management system to promote local universities’ further development

Burnout and study engagement among medical students at Sun Yat-sen University, China: A cross-sectional study.

This study aims to investigate burnout and study engagement among medical students at Sun Yat-sen University, China.A cross-sectional survey was conducted among undergraduate medical students of Sun Yat-sen University, China. A total of 453 undergraduate students completed a self-administered, structured questionnaire between January and February, 2016. Burnout and study engagement were measured using the Maslach Burnout Inventory-Student Survey (MBI-SS) and the UTRECHT Work Engagement Scale-Students (UWES-S), respectively. Subjects who scored high in emotional exhaustion subscale, high in cynicism subscale, and low in professional efficacy subscale simultaneously were graded as having high risk of burnout. Independent sample t tests and chi-square tests were used to compare the differences in burnout and work engagement between genders, majors, and grade levels.The means (standard deviations) of the MBI-SS subscales were 3.42 (1.45) for emotional exhaustion, 2.34 (1.64) for cynicism, and 3.04 (1.30) for professional efficacy. The means (standard deviations) of the UWES-S subscales were 3.13 (1.49) for vigor, 3.44 (1.47) for dedication and 3.00 (1.51) for absorption. Approximately 1 in 11 students experienced a high risk of burnout. There were no statistically significant gender differences in burnout and study engagement. There were also no statistically significant differences in burnout and study engagement subscales according to student major. Students in higher grades displayed increased burnout risk, higher mean burnout subscale score of cynicism, lower mean burnout subscale score of professional efficacy, and decreased mean study engagement subscale scores of dedication and absorption. There were strong correlations within study engagement subscales.Chinese medical students in this university experience a high level of burnout. Students at higher-grade level experience more burnout and decreased study engagement compared with students in lower level

Enhancement of recombinant myricetin on the radiosensitivity of lung cancer A549 and H1299 cells

OBJECTIVE: Myricetin, a common dietary flavonoid is widely distributed in fruits and vegetables, and is used as a health food supplement based on its immune function, anti-oxidation, anti-tumor, and anti-inflammatory properties. The aim of this study was to investigate the effects of myricetin on combination with radiotherapy enhance radiosensitivity of lung cancer A549 and H1299 cells. METHODS: A549 cells and H1299 cells were exposed to X-ray with or without myricetin treatment. Colony formation assays, CCK-8 assay, flow cytometry and Caspase-3 level detection were used to evaluate the radiosensitization activity of myricetin on cell proliferation and apoptosis in vitro. Nude mouse tumor xenograft model was built to assessed radiosensitization effect of myricetin in vivo. RESULTS: Compared with the exposed group without myricetin treatment, the groups treated with myricetin showed significantly suppressed cell surviving fraction and proliferation, increased the cell apoptosis and increased Caspase-3 protein expression after X-ray exposure in vitro. And in vivo assay, growth speed of tumor xenografts was significantly decreased in irradiated mice treated with myricetin. CONCLUSIONS: The study demonstrated both in vitro and in vivo evidence that combination of myricetin with radiotherapy can enhance tumor radiosensitivity of pulmonary carcinoma A549 and H1299 cells, and myricetin could be a potential radiosensitizer for lung cancer therapy. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/579151800121063

A 60-year record of 129I in Taal Lake sediments (Philippines): Influenceof human nuclear activities at low latitude region

The influence of human nuclear activities on environmental radioactivity is not well known at low latitude regions that are distant from nuclear test sites and nuclear facilities. A sediment core collected from Taal Lake in the central Philippines was analyzed for 129I and 127I to investigate this influence in a low-latitude terrestrial system. A baseline of 129I/127I atomic ratios was established at (2.04e5.14) * 10-12&nbsp;in the pre-nuclear era in this region. Controlled by the northeasterly equatorial trade winds, increased 129I/127I ratios of (20.1e69.3) * 10-12 suggest that atmospheric nuclear weapons tests at the Pacific Proving Grounds in the central Pacific Ocean was the major source of 129I in the sediment during 1956-1962. The 129I/127I ratios, up to 157.5*10-12 after 1964, indicate a strong influence by European nuclear fuel reprocessing plants. The East Asian Winter Monsoon is found to be the dominant driving force in the atmospheric dispersion of radioactive iodine (129I) from the European nuclear fuel reprocessing plants to Southeast Asia, which is also important for dispersion of other airborne pollutants from the middle-high to low latitude regions. A significant 129I/127I peak at 42.8 cm in the Taal Lake core appears to be the signal of the Chernobyl accident in 1986. In addition, volcanic activities are reflected in the iodine isotope profiles in the sediment core, suggesting the potential of using iodine isotopes as an indicator of volcanic eruptions.<br style="line-height: normal; text-align: -webkit-auto; text-size-adjust: auto;" /

Down-regulated miR-9 and miR-433 in human gastric carcinoma

<p>Abstract</p> <p>Background</p> <p>MircoRNAs(miRNAs) are short, endogenously non-coding RNAs. The abnormal expression of miRNAs may be valuable for the diagnosis and treatment of tumors.</p> <p>Methods</p> <p>To screening the special miRNAs in gastric carcinoma, expression level of miRNAs in gastric carcinoma and normal gaster samples were detected by miRNA gene chip. Then, the expressions of miR-9 and miR-433 in gastric carcinoma tissue and SGC7901 cell line were validated by qRT-PCR. GRB2 and RAB34, targets of miR-433 and miR-9 respectively, were detected by Western blot.</p> <p>Results</p> <p>We found 19 miRNAs and 7 miRNAs were down-regulated and up-regulated respectively. Compared with normal gaster samples, our data showed that miR-9 and miR-433 were down-regulated in gastric carcinoma. Meanwhile, we also found that miR-433 and miR-9 regulated the expression levels of GRB2 and RAB34 respectively.</p> <p>Conclusion</p> <p>Our data show miR-9 and miR-433 was down-regulated in gastric carcinoma. The targets of miR-433 and miR-9 were tumor-associated proteins GRB2 and RAB34 respectively. This result provided the related information of miRNAs in gastric carcinoma.</p

Ekonomski rast i emisija ugljika u Kini: Kuznetsova krivulja prostorne ekonometrije

Economic development has largely contributed to the increment of CO2 emission. This study uses spatial econometric models to investigate the relationship between economic growth and carbon emission in China with data of 30 provinces of China during the period of 2000 to 2012. Results show that the relationship between carbon emission and economic growth in China during the recent decade has the development tendency toward an inverse U-shaped curve, approximately confirming the carbon emission’s Kuznets curve hypothesis in China. There exists a significant spatial correlation between carbon emission and economic growth,implying that carbon emission in a province may be influenced by economic growth in adjacent provinces. When economic growth reaches 279.91 million Yuan/km2 GDP (at a comparable price in 2000), the contradiction between economic growth and carbon emission begins to be gradually alleviated. These findings provide new insights and valuable information for reducing carbon emissions in China.Gospodarski razvoj uvelike je pridonio povećanju emisije CO2. Ova studija koristi prostorne ekonometrijske modele za istraživanje odnosa između gospodarskog rasta i emisije ugljika u Kini s podacima iz 30 pokrajina Kine u razdoblju od 2000. do 2012. godine. Rezultati pokazuju da tijekom posljednjeg desetljeća odnos emisije ugljika i gospodarskog rasta u Kini ima tendenciju razvoja prema inverznoj krivulji U-oblika, približno potvrđujući hipotezu Kuznetsove krivulje emisije ugljika u Kini. Postoji značajna prostorna povezanost između emisije ugljika i ekonomskog rasta, što implicira da na emisiju ugljika u pokrajini može utjecati gospodarski rast u susjednim pokrajinama. Nakon što je ekonomski rast dosegnuo omjer od 279,91 milijuna Yuan/km2 BDP-a (usporediva cijena u 2000. godini), kontradikcija između gospodarskog rasta i emisije ugljika počinje se postupno ublažavati. Ovi rezultati pružaju nove uvide i vrijedne informacije kako reducirati emisije ugljika u Kini