A pair of diastereoisomeric <i>C</i>-glucofuranosyl flavones from the flowers of <i>Gypsophila oldhamiana</i>

Two new C-glucofuranosyl flavones apigenin 6-C-β-glucofuranoside (1) and apigenin 6-C-α-glucofuranoside (2) together with four known compounds (3–6) were isolated from the flowers of Gypsophila oldhamiana. Their structures were elucidated on the basis of extensive spectroscopic analyses. These compounds were evaluated for the cytotoxic activities against four human cancer cell lines and did not exhibit any significant bioactivities (IC50 values > 10 μM).</p

A,D-<i>seco</i>-Limonoids from the Stems of <i>Clausena emarginata</i>

Twelve new A,D-<i>seco</i>-limonoids, clauemargines A–L (<b>1</b>–<b>12</b>), and three known analogues were isolated from the stems of <i>Clausena emarginata</i>. The absolute configurations of <b>1</b> and <b>5</b> were confirmed by X-ray crystallography and ECD spectroscopy, respectively. Compounds <b>1</b>, <b>2</b>, <b>8</b>–<b>10</b>, and <b>13</b> showed moderate inhibitory effects on LPS-induced NO production (IC₅₀ values < 10 μM)