Examining the Role of Semantic Similarity in Online Restaurant Review Evaluations

Both language and image are critical for the grasp of information embedded in online reviews. While a large quantity of research has focused on the role of textual features and visual features separately, the specific role of similarity between textual and visual information in online review evaluations (e.g., review usefulness and review enjoyment) remains unaddressed. Thus, drawing on dual coding theory, this study attempts to investigate the impacts of textual and visual features on review evaluations by employing the Latent Dirichlet Allocation (LDA) topic modeling and Google Vision API’s web detection techniques in the context of online restaurant review (ORR). Moreover, the moderating role of semantic similarity is examined in the relationships between textual/visual features and ORR evaluations. It is believed that this study could provide implications on information comprehension, draw consumer interest, and provide suggestions for restaurant managers to tune levels of review evaluation in a proper manner

A Study on Seed Damage in Plating Electrolyte and Its Repairing in Cu Damascene Metallization

In this study, we observed the changes in the film properties of a Cu seed layer with its damage and repair. The immersion of the Cu seed layer in a sulfuric-acid-based plating electrolyte can result in damage to the Cu seed layer by the dissolution of the native Cu oxide and corrosion of Cu, leading to defects in the subsequent electrodeposited layer. The damaged seed layer was repaired using electroless plating. Cu re-covered the surface and the crystal structure of the seed layer was rebuilt and, finally, the filling characteristic was improved into superfilling in Cu electroplating for the damascene process. Electroless repairing, however, increased the seed roughness due to the low nucleation on the exposed barrier surface and the accompanying three-dimensional Cu growth. To refine the repairing process by inducing the nucleation on the barrier surface, Sn–Pd activation was adopted before the repair, and it reduced the surface roughness and improved the continuity of the seed layer effectively.This work was supported by the Korea Science and Engineering Foundation (KOSEF) through the Research Center for Energy Conversion and Storage (RCECS) and through the Nano R&D program funded by the Ministry of Education, Science and Technology (2009-0083223). It was also supported by a grant from the Fundamental R&D Program for Core Technology of Materials funded by the Ministry of Commerce, Industry and Energy, Republic of Korea

A small solitary non-parasitic hepatic cyst causing an intra-hepatic bile duct stricture: a case report

<p>Abstract</p> <p>Introduction</p> <p>We report an unusual presentation of a small hepatic cyst causing cholangitis.</p> <p>Case presentation</p> <p>A 70-year-old Asian man was hospitalized for aggravated chronic pain in the right upper portion of his abdomen. Fever developed after admission. Laboratory tests revealed elevated hepatobiliary enzymes, inflammatory markers and carbohydrate antigen 19-9 without hyperbilirubinemia. Ultrasound and computed tomography demonstrated dilatation of the left intra-hepatic bile ducts. Endoscopic retrograde cholangiopancreatography showed that the right intra-hepatic bile ducts were normally filled with contrast medium, but the left intra-hepatic bile ducts were not seen in the confluence. A left hepatectomy was performed because a hidden malignancy could not be excluded. The surgical findings showed no tumor around the bile duct but rather a 2 cm cyst in segment four of Couinaud's category of the liver around the hilum. The pathology report was a solitary non-parasitic hepatic cyst compressing the bile duct.</p> <p>Conclusion</p> <p>A very small solitary hepatic cyst might cause hepatic duct stricture if it is located near the hepatic hilum, and should be considered in the differential diagnosis of a hepatic duct stricture.</p

Longitudinal Patterns of Strengths Among Youth with Psychiatric Disorders: A Latent Profile Transition Analysis

A better understanding of variability in the strengths of youth with psychiatric disorders is critical as a strength-based approach can lead to recovery. This study aimed to identify subgroups of strengths among youth with mental disorders and determine whether subgroups changes were associated with mental health recovery. Youth with mental disorders (N = 2228) from a statewide database were identified in the state fiscal year of 2019. Using the latent profile analysis and latent transition analysis, we identified three strength profiles (i.e., essential, usable, and buildable). Over 90% of youth sustained or developed strengths over time. Positive transitions were associated with mental health recovery, symptom reduction, and personal recovery. Buildable strengths supported youth’s personal recovery independent of improving mental health needs. The findings suggest that subgroups of strengths may be a promising source for planning and tracking youth’s progress and guiding clinicians to more efficiently allocate community-based resources

Differential effects of luteolin and its glycosides on invasion and apoptosis in MDA-MB-231 triple-negative breast cancer cells

Luteolin is known to have anticancer activity in various ca ncers. Recent studies have shown that luteolin glyco- sides, such as luteolin-8- C - β -fucopyranoside, 7-methoxy-luteolin-8-C- β -(6- deoxyxylopyranos-3-uloside) and lu- teolin-8-C- β - D -glucopyranoside, flavonoid s that are present in Arthraxon hispidus , exert antimigratory and anti- invasive effects, but no cytotoxic effect in estrogen receptor-positive MCF7 breast cancer cells. In the present study, we further investigated and compared differential effects of luteolin and its glycosides in MDA-MB-231 triple-negative breast cancer cells. Lute olin suppressed the expression of matrix metalloproteinase-9 and inhibited migration and invasion in MDA-MB-231 cells treated with the tumor promotor 12-O-tetradecanoylphorbol-13- acetate at non-cytotoxic concentrations (0, 5, and 10 μ M). Furthermore, at cytotoxic concentrations (20 and 40 μ M), luteolin induced apoptosis via extrinsic and intrinsic pathways in MDA-MB-231 cells. However, luteolin glycosides did not exert any cytotoxic, antimigratory, or anti-invasive effect in MDA-MB-231 cells . In brief, l u- teolin had both antimetastatic and cytotoxic effects on MDA-MB-231 cells, whereas luteolin glycosides had no effect on this cell line. Taking together the present results and our previous findings on the differential effects of luteolin and its glycosides on MDA-MB-231 and MCF-7 br east cancer cells, luteolin and its glycosides can be suggested as a potential candida te for breast cancer therapy

Electricity production by the application of a low voltage DC-DC boost converter to a continuously operating flat-plate microbial fuel cell

An ultra-low voltage customized DC-DC booster circuit was developed using a LTC3108 converter, and used continuously on a flat-plate microbial fuel cell (FPM) system. The boost converter successfully stepped up the microbial fuel cell (MFC) voltage from ~0.5 V to 3.3 and 5.0 V of outputs. The designed circuit and system displayed the dynamic variations of the source FPM as well as the output voltage through the designed three connection points within the booster circuit. The source MFC voltage was interrelated with the booster circuit and its performance, and it adapted to the set points of the booster dynamically. The maximum output power density of the MFC with the DC-DC booster circuit was 8.16 W/m3 compared to the maximum source FPM input power of 14.27 W/m3 at 100 Ω, showing a conversion efficiency of 26–57%, but with a 10-fold higher output than that of the source voltage. The combined LTC3108 with FPM supplied power for electronic devices using synthetic and real domestic wastewater. This report presents a promising strategy for utilizing the electrical energy produced from MFCs, and expands the applicability of bioelectrochemical systems with an improved energy efficiency of the present wastewater treatment system

Inhibitory Effect of KP-A038 on Osteoclastogenesis and Inflammatory Bone Loss Is Associated With Downregulation of Blimp1

Excessive osteoclastic activity results in pathological bone resorptive diseases, such as osteoporosis, periodontitis, and rheumatoid arthritis. As imidazole-containing compounds possess extensive therapeutic potential for the management of diverse diseases, we synthesized a series of imidazole derivatives and investigated their effects on osteoclast differentiation and function. In the present study, we found that a novel imidazole derivative, KP-A038, suppressed receptor activator of nuclear factor-κB ligand (RANKL)-mediated osteoclastogenesis and bone-resorbing activity in vitro and attenuated lipopolysaccharide (LPS)-induced bone destruction in vivo. KP-A038 significantly inhibited the induction of nuclear factor of activated T-cells, cytoplasmic 1 (NFATc1) and the expression of its target genes, including tartrate-resistant acid phosphatase (Acp5), cathepsin K (Ctsk), dendritic cell-specific transmembrane protein (Dcstamp), and matrix metallopeptidase 9 (Mmp9). KP-A038 upregulated the expression of negative regulators of osteoclast differentiation, such as interferon regulatory factor-8 (Irf8) and B-cell lymphoma 6 (Bcl6). Consistently, KP-A038 downregulated the expression of B lymphocyte-induced maturation protein-1 (Blimp1 encoded by Prdm1), a repressor for Irf8 and Bcl6. Moreover, administration of KP-A038 reduced LPS-induced bone erosion by suppressing osteoclast formation in vivo. Thus, our findings suggest that KP-A038 may serve as an effective therapeutic agent for the treatment and/or prevention of bone loss in pathological bone diseases, including osteoporosis and periodontitis