Graphene field-effect transistors based on boron nitride gate dielectrics

Graphene field-effect transistors are fabricated utilizing single-crystal hexagonal boron nitride (h-BN), an insulating isomorph of graphene, as the gate dielectric. The devices exhibit mobility values exceeding 10,000 cm2/V-sec and current saturation down to 500 nm channel lengths with intrinsic transconductance values above 400 mS/mm. The work demonstrates the favorable properties of using h-BN as a gate dielectric for graphene FETs.Comment: 4 pages, 8 figure

Thermal transport measurements of individual multiwalled nanotubes

The thermal conductivity and thermoelectric power of a single carbon nanotube were measured using a microfabricated suspended device. The observed thermal conductivity is more than 3000 W/K m at room temperature, which is two orders of magnitude higher than the estimation from previous experiments that used macroscopic mat samples. The temperature dependence of the thermal conductivity of nanotubes exhibits a peak at 320 K due to the onset of Umklapp phonon scattering. The measured thermoelectric power shows linear temperature dependence with a value of 80 $\mu$V/K at room temperature.Comment: 4 pages, figures include

User interface design for mobile-based sexual health interventions for young people: Design recommendations from a qualitative study on an online Chlamydia clinical care pathway

Background: The increasing pervasiveness of mobile technologies has given potential to transform healthcare by facilitating clinical management using software applications. These technologies may provide valuable tools in sexual health care and potentially overcome existing practical and cultural barriers to routine testing for sexually transmitted infections. In order to inform the design of a mobile health application for STIs that supports self-testing and self-management by linking diagnosis with online care pathways, we aimed to identify the dimensions and range of preferences for user interface design features among young people. Methods: Nine focus group discussions were conducted (n=49) with two age-stratified samples (16 to 18 and 19 to 24 year olds) of young people from Further Education colleges and Higher Education establishments. Discussions explored young people's views with regard to: the software interface; the presentation of information; and the ordering of interaction steps. Discussions were audio recorded and transcribed verbatim. Interview transcripts were analysed using thematic analysis. Results: Four over-arching themes emerged: privacy and security; credibility; user journey support; and the task-technology-context fit. From these themes, 20 user interface design recommendations for mobile health applications are proposed. For participants, although privacy was a major concern, security was not perceived as a major potential barrier as participants were generally unaware of potential security threats and inherently trusted new technology. Customisation also emerged as a key design preference to increase attractiveness and acceptability. Conclusions: Considerable effort should be focused on designing healthcare applications from the patient's perspective to maximise acceptability. The design recommendations proposed in this paper provide a valuable point of reference for the health design community to inform development of mobile-based health interventions for the diagnosis and treatment of a number of other conditions for this target group, while stimulating conversation across multidisciplinary communities

Formation energy and interaction of point defects in two-dimensional colloidal crystals

The manipulation of individual colloidal particles using optical tweezers has allowed vacancies to be created in two-dimensional (2d) colloidal crystals, with unprecedented possibility of real-time monitoring the dynamics of such defects (Nature {\bf 413}, 147 (2001)). In this Letter, we employ molecular dynamics (MD) simulations to calculate the formation energy of single defects and the binding energy between pairs of defects in a 2d colloidal crystal. In the light of our results, experimental observations of vacancies could be explained and then compared to simulation results for the interstitial defects. We see a remarkable similarity between our results for a 2d colloidal crystal and the 2d Wigner crystal (Phys. Rev. Lett. {\bf 86}, 492 (2001)). The results show that the formation energy to create a single interstitial is $12$ lower than that of the vacancy. Because the pair binding energies of the defects are strongly attractive for short distances, the ground state should correspond to bound pairs with the interstitial bound pairs being the most probable.Comment: 5 pages, 2 figure

Statistical mechanics of Floquet systems: the pervasive problem of near degeneracies

The statistical mechanics of periodically driven ("Floquet") systems in contact with a heat bath exhibits some radical differences from the traditional statistical mechanics of undriven systems. In Floquet systems all quasienergies can be placed in a finite frequency interval, and the number of near degeneracies in this interval grows without limit as the dimension N of the Hilbert space increases. This leads to pathologies, including drastic changes in the Floquet states, as N increases. In earlier work these difficulties were put aside by fixing N, while taking the coupling to the bath to be smaller than any quasienergy difference. This led to a simple explicit theory for the reduced density matrix, but with some major differences from the usual time independent statistical mechanics. We show that, for weak but finite coupling between system and heat bath, the accuracy of a calculation within the truncated Hilbert space spanned by the N lowest energy eigenstates of the undriven system is limited, as N increases indefinitely, only by the usual neglect of bath memory effects within the Born and Markov approximations. As we seek higher accuracy by increasing N, we inevitably encounter quasienergy differences smaller than the system-bath coupling. We therefore derive the steady state reduced density matrix without restriction on the size of quasienergy splittings. In general, it is no longer diagonal in the Floquet states. We analyze, in particular, the behavior near a weakly avoided crossing, where quasienergy near degeneracies routinely appear. The explicit form of our results for the denisty matrix gives a consistent prescription for the statistical mechanics for many periodically driven systems with N infinite, in spite of the Floquet state pathologies.Comment: 31 pages, 3 figure

A new dromaeosaurid (Dinosauria: Theropoda) from the Upper Cretaceous Wulansuhai Formation of Inner Mongolia, China

We describe a new dromaeosaurid theropod from the Upper Cretaceous Wulansuhai Formation of Bayan Mandahu, Inner Mongolia. The new taxon, Linheraptor exquisitus gen. et sp. nov., is based on an exceptionally well-preserved, nearly complete skeleton. This specimen represents the fifth dromaeosaurid taxon recovered from the Upper Cretaceous Djadokhta Formation and its laterally equivalent strata, which include the Wulansuhai Formation, and adds to the known diversity of Late Cretaceous dromaeosaurids. Linheraptor exquisitus closely resembles the recently reported Tsaagan mangas. Uniquely among dromaeosaurids, the two taxa share a large, anteriorly located maxillary fenestra and a contact between the jugal and the squamosal that excludes the postorbital from the infratemporal fenestra. These features suggest a sister-taxon relationship between L. exquisitus and T. mangas, which indicates the presence of a unique dromaeosaurid lineage in the Late Cretaceous of Asia. A number of cranial and dental features seen in L. exquisitus and T. mangas, and particularly some postcranial features of L. exquisitus, suggest that these two taxa are probably intermediate in systematic position between known basal and derived dromaeosaurids. The discovery of Linheraptor exquisitus is thus important for understanding the evolution of some salient features seen in the derived dromaeosaurids

Age-specific effects of childhood body mass index on multiple sclerosis risk

OBJECTIVE: Higher body mass index (BMI) during early life is thought to be a causal risk factor for multiple sclerosis (MS). We used longitudinal Mendelian randomisation (MR) to determine whether there is a critical window during which BMI influences MS risk. METHODS: Summary statistics for childhood BMI (n ~ 28,000 children) and for MS susceptibility were obtained from recent large genome-wide association studies (GWAS) (n = 14,802 MS, 26,703 controls). We generated exposure instruments for BMI during four non-overlapping age epochs (< 3 months, 3 months–1.5 years, 2–5 years, and 7–8 years) and performed MR using the inverse variance weighted method with standard sensitivity analyses. Multivariable MR was used to account for effects mediated via later-life BMI. RESULTS: For all age epochs other than birth, genetically determined higher BMI was associated with an increased liability to MS: Birth [Odds Ratio (OR) 0.81, 95% Confidence Interval (CI) 0.50–1.31, Number of Single-Nucleotide Polymorphisms (N(SNPs)) = 7, p = 0.39], Infancy (OR 1.18, 95% CI 1.04–1.33, N(SNPs) = 18, p = 0.01), Early childhood (OR 1.31, 95% CI 1.03–1.66, N(SNPs) = 4, p = 0.03), Later childhood (OR 1.34, 95% CI 1.08–1.66, N(SNPs) = 4, p = 0.01). Multivariable MR suggested that these effects may be mediated by effects on adult BMI. CONCLUSION: We provide evidence using MR that genetically determined higher BMI during early life is associated with increased MS risk. This effect may be driven by shared genetic architecture with later-life BMI. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00415-022-11161-4

Electronic compressibility of layer polarized bilayer graphene

We report on a capacitance study of dual gated bilayer graphene. The measured capacitance allows us to probe the electronic compressibility as a function of carrier density, temperature, and applied perpendicular electrical displacement D. As a band gap is induced with increasing D, the compressibility minimum at charge neutrality becomes deeper but remains finite, suggesting the presence of localized states within the energy gap. Temperature dependent capacitance measurements show that compressibility is sensitive to the intrinsic band gap. For large displacements, an additional peak appears in the compressibility as a function of density, corresponding to the presence of a 1-dimensional van Hove singularity (vHs) at the band edge arising from the quartic bilayer graphene band structure. For D > 0, the additional peak is observed only for electrons, while D < 0 the peak appears only for holes. This asymmetry that can be understood in terms of the finite interlayer separation and may be useful as a direct probe of the layer polarization