Synthesis and structural characterization of new oxorhenium and oxotechnetium complexes with XN2S-tetradentate semi-rigid ligands(X = O, S, N)

Twelve novel oxo-technetium and oxo-rhenium complexes based on N2S2-, N2SO- or N3S-tetradentate semi-rigid ligands have been synthesised and studied herein. By reacting the ligands with a slight excess of suitable [MO]3+ precursor (ReOCl3(PPh3)2 or [NBu4][99gTcOCl4]), the monoanionic complexes of general formula [MO(Ph–XN2S)]− could be easily produced in high yield. The complexes have been characterized by means of IR, electrospray mass spectrometry, elemental analysis, NMR and conductimetry. The crystal structures of [PPh4][ReO(Ph–ON2S)] 1b and [NBu4][99gTcO(Ph–ON2S)] 1c have been established. The [MO]3+ moiety was coordinated via the two deprotonated amide nitrogens, the oxygen and the terminal sulfur atoms in 1b and 1c. In both compounds, the ON2S coordination set is in the equatorial plane, and the complexes adopted a distorted square-pyramidal geometry with an axial oxo-group. The chemical and structural identity of the different prototypic complexes (rhenium, 99gTc complexes and their corresponding 99mTc radiocomplexes) have been also established by a comparative HPLC study

American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus

10.1002/acr.23834ARTHRITIS CARE & RESEARCH715579-59

Make or Buy: An Analysis of the Impacts of 3D Printing Operations, 3D Laser Scanning Technology, and Collaborative Product Lifecycle Management on Ship Maintenance and Modernization Cost Savings

Naval Postgraduate School Acquisition Research Progra

Benchmarking Naval Shipbuilding with 3D Laser Scanning, Additive Manufacturing, and Collaborative Product Lifecycle Management

Naval Postgraduate School Acquisition Research Progra

A methodology for improving the shipyard planning process: using KVA analysis, risk simulation and strategic real options / Graduate School of Business and Public Policy

The U.S. Navy must be extremely diligent with its maintenance policies to ensure that ships and submarines meet national defense objectives. Maximizing the Navy's readiness requires continuous process improvement and innovation, and making information technology (IT) acquisitions that leverage technological advances to reduce costs and increase efficiency levels. Measurement tools are essential to define, capture, measure and evaluate the total value of potential IT acquisitions to ensure the likelihood of success. This paper describes research conducted on the Knowledge Value Added/Real Options (KVA+RO) Valuation Framework. A comprehensive tool, KVA+RO was applied to Naval maintenance processes in a case study analyzing the potential impact of Commercial-off-the-shelf (COTS) technology on ship yard planning processes. Specific technology, including three-dimensional (3D) laser scanning and collaborative Product Lifecycle Management (PLM) solutions, were evaluated under three scenarios. Real Options analysis was also performed to determine the prospective value of strategic options over a three-year period.Approved for public release; distribution is unlimited

A methodology for improving the shipyard planning process: using KVA analysis, risk simulation and strategic real options / Acquisition Management

Acquisition research (Graduate School of Business & Public Policy)The U.S. Navy must be extremely diligent with its maintenance policies to ensure that ships and submarines meet national defense objectives. Maximizing the Navy's readiness requires continuous process improvement and innovation, and making information technology (IT) acquisitions that leverage technological advances to reduce costs and increase efficiency levels. Measurement tools are essential to define, capture, measure and evaluate the total value of potential IT acquisitions to ensure the likelihood of success. This paper describes research conducted on the Knowledge Value Added/Real Options (KVA+RO) Valuation Framework. A comprehensive tool, KVA+RO was applied to Naval maintenance processes in a case study analyzing the potential impact of Commercial-off-the-shelf (COTS) technology on ship yard planning processes. Specific technology, including three-dimensional (3D) laser scanning and collaborative Product Lifecycle Management (PLM) solutions, were evaluated under three scenarios. Real Options analysis was also performed to determine the prospective value of strategic options over a three-year period

Make or Buy: An Analysis of the Impacts of 3D Printing Operations, 3D Laser Scanning Technology, and Collaborative Product Life-Cycle Management on Ship Maintenance and Modernization Cost Savings

Naval Postgraduate School Acquisition Research Progra

AEGIS and Ship Self-Defense (SSDS) Platforms: Using KVA Analysis, Risk Simulation and Strategic Real Options to Assess Operational Effectiveness

Sponsored Report (for Acquisition Research Program)Modern, analytical tools are critical to understand the impact of open architecture technology and open business models on naval warfighting processes and procedures. These tools must measure the operational value of a system from an end-user, warfighter perspective, identify areas of deficiencies in capabilities, and flag areas for potential acquisitions. One advantage of examining open architected system upgrade options from a warfighter perspective is that the new systems can be integrated with reengineered processes more easily leading to improved process performance. This perspective, using OA to upgrade existing IWS systems, ensures that upgrades will lead to improved warfighting capabilities. Traditional measurement tools used for cost analysis cannot calculate the total value of upgrading a system to support an improved warfighting capability, particularly the improved operational value resulting from reengineering of warfighting processes. The Knowledge Value Added/Real Options (KVA+RO) Valuation Framework is a tool designed to assist decision-makers in making technology acquisitions. This paper describes research using the KVA+RO framework for estimating return on investment, in an open architecture approach, to upgrading and/or replacing aging IWS AEGIS and SSDS systems. The results of the research indicated that using the open architecture (OA)model, in combination with the ''leave and layer'' approach, was approximately five times more valuable than the current proprietary approach to system replacement and was approximately twice as valuable as a complete retrofit and replace strategy. ''Leave and layer'' provided the highest return on investment for replacing the AEGIS system with the lowest risk. The ultimate success of the OA approach is dependent on the ability of the multiple parties to system development and deployment to collaborate. Collaboration, along with the tools that facilitate collaboration, is critical to the success of any of the OA approaches.Naval Postgraduate School Acquisition Research ProgramApproved for public release; distribution is unlimited

AEGIS and Ship Self-Defense System (SSDS) platforms: using KVA analysis, risk simulation and strategic real options to assess operational effectiveness

Acquisition research (Graduate School of Business & Public Policy)Modern, analytical tools are critical to understand the impact of open architecture technology and business models on naval warfighting processes and procedures. The Knowledge Value Added/Real Options (KVA+RO) Valuation Framework is a tool set designed to assist decision-makers in making technology acquisitions. This paper describes research using the KVA+RO framework for estimating return on investment, in an open architecture approach, to upgrading and/or replacing the aging IWS AEGIS and SSDS systems. The results of the research demonstrated that the leave and layer approach for incrementally replacing AEGIS system modules was the most valuable strategic option, providing the highest return on investment with the lowest risk. This study measured the operational value of various system replacement options from an end-user perspective, identified areas of deficiencies in capabilities, and flagged areas for potential system improvements and acquisitions. The potential costs and cost savings for each option were also calculated.Approved for public release; distribution is unlimited

Measuring the Return on Investment and Real Option Value of Weather Sensor Bundles for Air Force Unmanned Aerial Vehicles

Naval Postgraduate School Acquisition Research Progra