4,317 research outputs found
Mechanismus der enzymatischen Freisetzung von Acetaldehyd aus âaktivem Acetaldehydâ (α-hydroxyaethyl-2-thiaminpyrophosphat)
1. 1.Die Freisetzung von Acetaldehyd aus âAktivem Acetaldehydâ mit gereinigter Apopyruvatdecarboxylase aus Bierhefe wird durch. Thiaminpyrophosphat gehemmt. Diese Konkurrenzhemmung erklĂ€rt (zumindest teilweise) die langsame Freisetzung von Acetaldehyd beim enzymatischen Umsatz von PrĂ€paraten, die viel Thiamin-pyrophosphat enthalten.
2. 2. Die Freisetzung von Acetaldehyd aus âAktivem Acetaldehydâ mit Apo-carboxylase erfolgt nicht in einer frĂŒher von uns diskutierten Austauschreaktion mit Pyruvat, sondern in einer direkten Reaktion: Aktiver Acetaldehyd Ă„ Acetaldehyd + TPP.1. 1. The enzymic formation of acetaldehyde from α-hydroxyethyl thiamine pyrophosphate with purified apopyrubate decarboxylase from yeast is inhibited by thiamine pyrophosphate. This inhibition explains (at least partly) the slow enzymic production of acetaldehyde from α-hydroxyethyl thiamine pyrophosphate preparations containing a considerable amount of thiamine pyrophosphate.
2. 2. The enzymic formation of acetaldehyde from α-hydroxyethyl thiamine pyrophosphate with apocarboxylase does not take place in form of an exchange reaction with pyruvate, as discussed earlier, but in form of the direct reaction: α-hydroxyethyl thiamine pyrophosphate â acetaldehyde + thiamine pyrophosphate
Are Suburban Firms More Likely to Discriminate Against African Americans?
This paper presents a test of the hypothesis that employers in suburban locations are more likely to discriminate against African Americans than are employers located in central cities. Using a difference-in-difference framework, we compare central-city/suburban differences in racial hiring outcomes for firms where a white person is in charge of hiring (white employers, for short) to similar geographic differences in outcomes for firms where a black person is in charge of hiring (black employers). We find that both suburban black and white employers hire fewer blacks than their central-city counterparts. Moreover, the central-city/suburban hiring gap among black employers is as large as, or larger than, that of white employers. Suburban black employers, however, receive many more applications from blacks and hire more blacks than do white firms in either location.
Linear Imperfections and Operational Aspects Induced by the D1 Multipole Errors for the LHC Upgrade Phase I
In addition to the dynamic aperture as a general machine parameter that has to be optimized in the LHC upgrade machine, strong lower order multipoles will lead to a series of problems for the operation of the machine. A direct influence on the linear beam optics (beta beating, tune shift and coupling) from the a2, b2 multipoles is evident. Equally important however are the multipole coefficients of the next higher order n=3 via the feed down effect. The foreseen half crossing angle of about 205 ”rad at the IP creates large offsets in the D1 magnet that finally lead again to a strong a2, b2 errors. The estimates presented in this paper show a distortion in the order of several percent for the beta beat and a considerable shift of the working point. Even after compensation of these effects an influence on the machine performance is expected during machine operation and a further reduction of the multipole coefficients, especially in the case of the D1 magnet, might be needed
Green's Relations in Finite Transformation Semigroups
We consider the complexity of Green's relations when the semigroup is given
by transformations on a finite set. Green's relations can be defined by
reachability in the (right/left/two-sided) Cayley graph. The equivalence
classes then correspond to the strongly connected components. It is not
difficult to show that, in the worst case, the number of equivalence classes is
in the same order of magnitude as the number of elements. Another important
parameter is the maximal length of a chain of components. Our main contribution
is an exponential lower bound for this parameter. There is a simple
construction for an arbitrary set of generators. However, the proof for
constant alphabet is rather involved. Our results also apply to automata and
their syntactic semigroups.Comment: Full version of a paper submitted to CSR 2017 on 2016-12-1
A Roundtable Conversation: Feminist Collaborative Ethos in International Law
This roundtable discussion focuses on the collective commitment and the praxis of a feminist collaborative ethos in international law to imagine and centre alternative futures in the field. This discussion took place as part of the virtual workshop âInternational Law Dis/Oriented: Queer Legacies, and Queer Futures Workshopâ from which this special issue emerged. In this transcript of the roundtable, Shaimaa Abdelkarim, Farnush Ghadery, and Rohini Sen discuss with Lena Holzer how turning to feminist collectivity â focused on care, collaboration, and solidarity â can help to disrupt and push against gendered, racialised, and colonial power structures embedded in academic spaces. They examine their intertwined positionalities along with various pedagogical and methodological approaches to determine the functions of critical feminist and queer thoughts in international law. Inculcating a praxis of feminist collaborative ethos in the scholarship and teaching of international law, they hope to present a challenge to the artificial individualisation of the profession and its increasing neoliberalisation
Measurements of heavy ion beam losses from collimation
The collimation efficiency for Pb ion beams in the LHC is predicted to be
lower than requirements. Nuclear fragmentation and electromagnetic dissociation
in the primary collimators create fragments with a wide range of Z/A ratios,
which are not intercepted by the secondary collimators but lost where the
dispersion has grown sufficiently large. In this article we present
measurements and simulations of loss patterns generated by a prototype LHC
collimator in the CERN SPS. Measurements were performed at two different
energies and angles of the collimator. We also compare with proton loss maps
and find a qualitative difference between Pb ions and protons, with the maximum
loss rate observed at different places in the ring. This behavior was predicted
by simulations and provides a valuable benchmark of our understanding of ion
beam losses caused by collimation.Comment: 12 pages, 20 figure
zur Wirkung von 2,5-Dimethoxy-Ă€thoxy-3,6-bis-Ă€thylenimin-benzochinon-1,4 (BAYER A 139) auf die Glykolyse von Ascites-Tumorzellen
Molecular studies on the seasonal occurrence and development of five myxozoans in farmed Salmo trutta L.
Five myxozoan species, Tetracapsuloides bryosalmonae, Sphaerospora truttae, Chloromyxum schurovi, Chloromyxum truttae and a Myxobolus species were detected in farmed brown trout, Salmo trutta L. from Central Scotland. Using PCR and in situ hybridization, this study investigated the seasonal occurrence and tissue location of these species in young of the year brown trout. C. schurovi, C. truttae and Myxobolus sp. were first detected in brown trout in April, 2 months before T. bryosalmonae and S. truttae. T. bryosalmonae and S. truttae showed proliferation in the blood with intravascular stages of T. bryosalmonae accumulating in the heart. In contrast, only small amounts of PCR products of C. schurovi and C. truttae were obtained from the blood, suggesting that these species use the vascular system for transport but proliferate only in their target tissues from which large amounts of PCR product were obtained and where parasites were visible in histological sections. Large amounts of PCR product were obtained for T. bryosalmonae, S. truttae and both Chloromyxum species from the gills of brown trout, suggesting the gills as entry locus for these species. The neurotropic Myxobolus species formed plasmodia predominantly in the peripheral nerves, possibly indicating an entry route through the skin. Presporogonic stages of all other species had disappeared by September and mature spores were present from August onwards
The FCC-ee Interaction Region Magnet Design
The design of the region close to the interaction point of the FCC-ee
experiments is especially challenging. The beams collide at an angle (+-15
mrad) in the high-field region of the detector solenoid. Moreover, the very low
vertical beta_y* of the machine necessitates that the final focusing
quadrupoles have a distance from the IP (L*) of around 2 m and therefore are
inside the main detector solenoid. The beams should be screened from the effect
of the detector magnetic field, and the emittance blow-up due to vertical
dispersion in the interaction region should be minimized, while leaving enough
space for detector components. Crosstalk between the two final focus
quadrupoles, only about 6 cm apart at the tip, should also be minimized.Comment: Poster presented at IPAC16, May 8-13, Busan, Kore
EHR-Based Care Coordination Performance Measures in Ambulatory Care
Describes electronic health record-based measures for assessing coordination in referrals, including information communicated with referral, communication to patient, and specialist report to primary care physician. Offers preliminary evaluation findings
- âŠ