4 research outputs found

    Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020

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    We show the distribution of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three genomic nomenclature systems to all sequence data from the World Health Organization European Region available until 10 July 2020. We highlight the importance of real-time sequencing and data dissemination in a pandemic situation, compare the nomenclatures and lay a foundation for future European genomic surveillance of SARS-CoV-2

    A management-scale investigation of consistent individual differences in behaviour and trapping bias in Sea Lamprey (Petromyzon marinus)

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    The Sea Lamprey (Petromyzon marinus) is invasive in the Laurentian Great Lakes. Trapping in large rivers could suppress Sea Lamprey recruitment by removing migrating adults prior to spawning. Currently, the proportion of Sea Lamprey trapped (efficiency) is too low for control purposes, possibly because trapping is biased toward certain behavioural types. We tested if individual differences in time to enter a novel environment (risk-taking) and proportion of time moving (activity) under standardized laboratory conditions were correlated with time to encounter and enter a trap in the field. 638 Sea Lamprey were tagged, assessed for risk-taking and activity in sequential trials, and released in the river to be trapped. In the laboratory, individuals differed consistently in risk-taking and activity behaviours, and more active individuals entered a simulated trap sooner than less active individuals. In the field, however, the times to first trap encounter, and capture in a trap, were not correlated with risk-taking or activity. Our study provides a novel demonstration of how patterns from small-scale behavioural studies may not extend to management-scale applications.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author

    Leveraging European European infrastructures to access 1 million human genomes by 2022

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    Human genomics is undergoing a step change from being a predominantly research-driven activity to one driven through health care as many countries in Europe now have nascent precision medicine programmes. To maximize the value of the genomic data generated, these data will need to be shared between institutions and across countries. In recognition of this challenge, 21 European countries recently signed a declaration to transnationally share data on at least 1 million human genomes by 2022. In this Roadmap, we identify the challenges of data sharing across borders and demonstrate that European research infrastructures are well-positioned to support the rapid implementation of widespread genomic data access
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