24,157 research outputs found
Flight-measured laminar boundary-layer transition phenomena including stability theory analysis
Flight experiments were conducted on a single-engine turboprop aircraft fitted with a 92-in-chord, 3-ft-span natural laminar flow glove at glove section lift coefficients from 0.15 to 1.10. The boundary-layer transition measurement methods used included sublimating chemicals and surface hot-film sensors. Transition occurred downstream of the minimum pressure point. Hot-film sensors provided a well-defined indication of laminar, laminar-separation, transitional, and turbulent boundary layers. Theoretical calculations of the boundary-layer parameters provided close agreement between the predicted laminar-separation point and the measured transition location. Tollmien-Schlichting (T-S) wave growth n-factors between 15 and 17 were calculated at the predicted point of laminar separation. These results suggest that for many practical airplane cruise conditions, laminar separation (as opposed to T-S instability) is the major cause of transition in predominantly two-dimensional flows
Improved ontology for eukaryotic single-exon coding sequences in biological databases
Indexación: Scopus.Efficient extraction of knowledge from biological data requires the development of structured vocabularies to unambiguously define biological terms. This paper proposes descriptions and definitions to disambiguate the term 'single-exon gene'. Eukaryotic Single-Exon Genes (SEGs) have been defined as genes that do not have introns in their protein coding sequences. They have been studied not only to determine their origin and evolution but also because their expression has been linked to several types of human cancer and neurological/developmental disorders and many exhibit tissue-specific transcription. Unfortunately, the term 'SEGs' is rife with ambiguity, leading to biological misinterpretations. In the classic definition, no distinction is made between SEGs that harbor introns in their untranslated regions (UTRs) versus those without. This distinction is important to make because the presence of introns in UTRs affects transcriptional regulation and post-transcriptional processing of the mRNA. In addition, recent whole-transcriptome shotgun sequencing has led to the discovery of many examples of single-exon mRNAs that arise from alternative splicing of multi-exon genes, these single-exon isoforms are being confused with SEGs despite their clearly different origin. The increasing expansion of RNA-seq datasets makes it imperative to distinguish the different SEG types before annotation errors become indelibly propagated in biological databases. This paper develops a structured vocabulary for their disambiguation, allowing a major reassessment of their evolutionary trajectories, regulation, RNA processing and transport, and provides the opportunity to improve the detection of gene associations with disorders including cancers, neurological and developmental diseases. © The Author(s) 2018. Published by Oxford University Press.https://academic.oup.com/database/article/doi/10.1093/database/bay089/509943
Glass transitions and shear thickening suspension rheology
We introduce a class of simple models for shear thickening and/ or `jamming'
in colloidal suspensions. These are based on schematic mode coupling theory
(MCT) of the glass transition, having a memory term that depends on a density
variable, and on both the shear stress and the shear rate. (Tensorial aspects
of the rheology, such as normal stresses, are ignored for simplicity.) We
calculate steady-state flow curves and correlation functions. Depending on
model parameters, we find a range of rheological behaviours, including
`S-shaped' flow curves, indicating discontinuous shear thickening, and
stress-induced transitions from a fluid to a nonergodic (jammed) state, showing
zero flow rate in an interval of applied stress. The shear thickening and
jamming scenarios that we explore appear broadly consistent with experiments on
dense colloids close to the glass transition, despite the fact that we ignore
hydrodynamic interactions. In particular, the jamming transition we propose is
conceptually quite different from various hydrodynamic mechanisms of shear
thickening in the literature, although the latter might remain pertinent at
lower colloid densities. Our jammed state is a stress-induced glass, but its
nonergodicity transitions have an analytical structure distinct from that of
the conventional MCT glass transition.Comment: 33 pages; 19 figure
An experimental and theoretical investigation of deposition patterns from an agricultural airplane
A flight test program has been conducted with a representative agricultural airplane to provide data for validating a computer program model which predicts aerially applied particle deposition. Test procedures and the data from this test are presented and discussed. The computer program features are summarized, and comparisons of predicted and measured particle deposition are presented. Applications of the computer program for spray pattern improvement are illustrated
Natural laminar flow experiments on modern airplane surfaces
Flight and wind-tunnel natural laminar flow experiments have been conducted on various lifting and nonlifting surfaces of several airplanes at unit Reynolds numbers between 0.63 x 10 to the 6th power/ft and 3.08 x 10 to the 6th power/ft, at Mach numbers from 0.1 to 0.7, and at lifting surface leading-edge sweep angles from 0 deg to 63 deg. The airplanes tested were selected to provide relatively stiff skin conditions, free from significant roughness and waviness, on smooth modern production-type airframes. The observed transition locations typically occurred downstream of the measured or calculated pressure peak locations for the test conditions involved. No discernible effects on transition due to surface waviness were observed on any of the surfaces tested. None of the measured heights of surface waviness exceeded the empirically predicted allowable surface waviness. Experimental results consistent with spanwise contamination criteria were observed. Large changes in flight-measured performance and stability and control resulted from loss of laminar flow by forced transition. Rain effects on the laminar boundary layer caused stick-fixed nose-down pitch-trim changes in two of the airplanes tested. No effect on transition was observed for flight through low-altitude liquid-phase clouds. These observations indicate the importance of fixed-transition tests as a standard flight testing procedure for modern smooth airframes
Jamming transitions in a schematic model of suspension rheology
We study the steady-state response to applied stress in a simple scalar model
of sheared colloids. Our model is based on a schematic (F2) model of the glass
transition, with a memory term that depends on both stress and shear rate. For
suitable parameters, we find transitions from a fluid to a nonergodic, jammed
state, showing zero flow rate in an interval of applied stress. Although the
jammed state is a glass, we predict that jamming transitions have an analytical
structure distinct from that of the conventional mode coupling glass
transition. The static jamming transition we discuss is also distinct from
hydrodynamic shear thickening.Comment: 7 pages; 3 figures; improved version with added references. Accepted
for publication in Europhysics Letter
A comparison of the in vitro and in planta responses of Phytophthora cinnamomi isolates to phosphite
Research in plant pathology often relies on testing interactions between a fungicide and a pathogen in vitro and extrapolating from these results what may happen in planta. Likewise, results from glasshouse experiments are used to estimate what will happen if the fungicide is applied in the field. However, it is difficult to obtain conditions in vitro and in the glasshouse which reflect the conditions where the fungicide may eventually be used, in the field.
The aim of this paper is to compare results of the effect of phosphite on P. cinnamomi isolates in vitro and in planta
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Languages and Learning at Key Stage 2: A Longitudinal Study Final Report
In 2006, The Open University, the University of Southampton and Canterbury Christ Church University were commissioned by the then Department for Education and Skills (DfES), now Department for Children, Schools and Families (DCSF) to conduct a three-year longitudinal study of languages learning at Key Stage 2 (KS2). The qualitative study was designed to explore provision, practice and developments over three school years between 2006/07 and 2008/09 in a sample of primary schools and explore children’s achievement in oracy and literacy, as well as the possible broader cross-curricular impact of languages learning
Total focussing method for volumetric imaging in immersion non destructive evaluation
This paper describes the use of a 550 (25x22) element 2MHz 2D piezoelectric composite array in immersion mode to image an aluminum test block containing a collection of artificial defects. The defects included a 1mm diameter side-drilled hole, a collection of 1mm slot defects with varying degrees of skew to the normal and a flat bottomed hole. The data collection was carried out using the full matrix capture; a scanning procedure was developed to allow the operation of the large element count array through a conventional 64-channel phased array controller. A 3D TFM algorithm capable of imaging in a dual media environment was implemented in MATLAB for the offline processing the raw scan data. This algorithm facilitates the creation of 3D images of defects while accounting for refraction effects at material boundaries. In each of the test samples interrogated the defects, and their spatial position, are readily identified using TFM. Defect directional information has been characterized using VTFM for defect exhibiting angles up to and including 45o of skew
A Reevaluation of Sexual Dimorphism in the Postcranium of the Chasmosaurine Ceratopsid Chasmosaurus belli (Dinosauria: Ornithischia)
The sexual dimorphism attributed to Chasmosaurus belli by Sternberg (1927) is revisited and reevaluated. A reexamination of the two specimens originally considered by Sternberg reveals that they are less complete than first suggested, with only a moderate amount of overlapping material between them. Only a few of the postcranial elements (humeri, sternal plates, and presacral vertebrae) show evidence of dimorphism, the significance of which is either doubtful or equivocal. Instead of representing sexual dimorphs, it is likely that the two specimens belong to separate species, C. belli and C. russelli, as evidenced by their distinct frill morphologies and by their stratigraphic segregation within the Dinosaur Park Formation of Alberta. These findings emphasize the need to remain sceptical about claims advocating sexual dimorphism in the fossil record in the absence of statistical significance or stratigraphic control
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