4 research outputs found

    Color in selected dramas of Federico Garcia Lorca

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    Call number: LD2668 .T4 1966 H742Master of Scienc

    Musique et politique

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    Musiciens et chanteurs sont à l'origine de pratiques qui s'insèrent pleinement dans le jeu complexe des rapports sociaux. Aux stades de la création, de la production ou de la consommation, les musiques n'échappent jamais aux enjeux socio-culturels d'un lieu, d'une époque, d'une communauté humaine. Conformes ou dissidentes à l'égard des logiques dominantes, elles demeurent productrices d'émotions esthétiques et porteuses des liens sociaux. Les musiques sont des enjeux de pouvoir et certaines logiques économiques ou politiques peuvent conduire à leur instrumentalisation. L'histoire est malheureusement riche de ces musiciens annexés par des régimes politiques au destin funeste. Mais les musiques sont aussi porteuses d'identités culturelles voire d'appels à la résistance. Structurant des groupes sociaux, des communautés nationales, elles peuvent contribuer, par leur capacité mobilisatrice, à accentuer ou plus fréquemment à faire tomber les murs du racisme, de l'intolérance ou du totalitarisme. C'est qu'il n'est de pratique musicale que dans l'échange. C'est bien là toute l'ambiguïté et la richesse de cet objet, à la fois verbe codé, situé, et langage universel, transculturel. Elles méritent donc pleinement que les sociologues, les artistes, les mélomanes et les citoyens que nous sommes tous tentent de franchir ces miroirs du son qui nous renvoient les images parfois brouillées de nos sociétés

    Angioedema in Chronic Spontaneous Urticaria Is Underdiagnosed and Has a Substantial Impact : Analyses From ASSURE-CSU

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    Background: ASSURE-CSU revealed differences in physician and patient reporting of angioedema. This post hoc analysis was conducted to evaluate the actual rate of angioedema in the study population and explore differences between patients with and without angioedema. Methods: This international observational study assessed 673 patients with inadequately controlled chronic spontaneous urticaria (CSU). Physicians abstracted angioedema data from medical records, which were compared with patient-reported data. Patients in the Yes-angioedema category had angioedema reported in the medical record and a patient-reported source. For those in the No-angioedema category, angioedema was reported in neither the medical record nor a patient-reported source. Those in the Misaligned category had angioedema reported in only one source. Statistical comparisons between Yes-angioedema and No-angioedema categories were conducted for measures of CSU activity, health-related quality of life (HRQoL), productivity and healthcare resource utilization (HCRU). Regression analyses explored the relationship between Dermatology Life Quality Index (DLQI) score and angioedema, adjusting for important covariates. Results: Among evaluable patients, 259 (40.3%), 173 (26.9%) and 211 (32.8%) were in the Yes-angioedema, No-angioedema and Misaligned category, respectively. CSU activity and impact on HRQoL, productivity, and HCRU was greater for Yes-angioedema patients than No-angioedema patients. After covariate adjustment, mean DLQI score was significantly higher (indicating worse HRQoL) for patients with angioedema versus no angioedema (9.88 vs 7.27, P <.001). The Misaligned category had similar results with Yes-angioedema on all outcomes. Conclusions: Angioedema in CSU seems to be under-reported but has significant negative impacts on HRQoL, daily activities, HCRU and work compared with no angioedema

    The burden of chronic spontaneous urticaria is substantial : real-world evidence from ASSURE-CSU

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    Chronic spontaneous urticaria () can be debilitating, difficult to treat, and frustrating for patients and physicians. Real-world evidence for the burden of is limited. The objective of this study was to document disease duration, treatment history, and disease activity, as well as impact on health-related quality of life (oL) and work among patients with inadequately controlled , and to describe its humanistic, societal, and economic burden. This international observational study assessed a cohort of 673 adult patients with whose symptoms persisted for ≥12 months despite treatment. Demographics, disease characteristics, and healthcare resource use in the previous 12 months were collected from medical records. Patient-reported data on urticaria and angioedema symptoms, oL, and work productivity and activity impairment were collected from a survey and a diary. Almost 50% of patients had moderate-to-severe disease activity as reported by Urticaria Activity Score. Mean () Dermatology Life Quality Index and Chronic Urticaria Quality of Life Questionnaire scores were 9.1 (6.62) and 33.6 (20.99), respectively. Chronic spontaneous urticaria markedly interfered with sleep and daily activities. Angioedema in the previous 12 months was reported by 66% of enrolled patients and significantly affected oL. More than 20% of patients reported ≥1 hour per week of missed work; productivity impairment was 27%. These effects increased with increasing disease activity. Significant healthcare resources and costs were incurred to treat . Chronic spontaneous urticaria has considerable humanistic and economic impacts. Patients with greater disease activity and with angioedema experience greater oL impairments
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