Correlates of Hepatitis C Serostatus Disclosure in Rural Appalachian Kentucky

Aim: To identify demographic, behavioral, and interpersonal characteristics associated with hepatitis C (HCV) serostatus disclosure among adult, rural, high-risk people who use drugs (PWUD) in Appalachian Kentucky. Methods: Laboratory confirmed HCV antibody-positive participants (n=243), drawn from the fifth follow-up assessment of a longitudinal study of rural PWUD, completed interviewer-administered questionnaires eliciting demographic and interpersonal characteristics, risk behaviors, and information on HCV disclosure. Correlates of HCV disclosure were assessed using logistic regression. Results: Most (69.1%) reported disclosing their HCV-positive status to at least one of their social referents (current or past sex partners, current or past injection drug use (IDU) partners, family, friends, or spouse), but few told the people with whom they inject drugs (3.8% disclosed to current, and 1.4% disclosed to past IDU partners). In multivariate analysis, adjusting for confounders and time since HCV diagnosis, male gender (AOR=0.40, 95% CI [0.20, 0.78]), older age (AOR=0.96, 95% CI [0.92, 1.00]), lifetime history of injection drug use (AOR=0.26, 95% CI [0.07, 0.99]), and lifetime history of drug treatment (AOR=0.34, 95% CI [0.18, 0.65]) were associated with decreased odds of HCV disclosure. Conclusions: While most participants reported HCV disclosure, the almost complete absence of disclosure to current or former injection drug use partners was concerning. Although further research is warranted, it is clear that interventions are needed to encourage HCV disclosure among those most at risk of transmitting, or becoming infected with, HCV

Laser-Induced, Polarization Dependent Shape Transformation of Au/Ag Nanoparticles in Glass

Bimetallic, initially spherical Ag/Au nanoparticles in glass prepared by ion implantation have been irradiated with intense femtosecond laser pulses at intensities still below the damage threshold of the material surface. This high-intensity laser processing produces dichroism in the irradiated region, which can be assigned to the observed anisotropic nanoparticle shapes with preferential orientation of the longer particle axis along the direction of laser polarization. In addition, the particle sizes have considerably been increased upon processing

The influence of potassium on core and geodynamo evolution

We model the thermal evolution of the core and mantle using a parametrized convection scheme, and calculate the entropy available to drive the geodynamo as a function of time. The cooling of the core is controlled by the rate at which the mantle can remove heat. Rapid core cooling favours the operation of a geodynamo but creates an inner core that is too large; slower cooling reduces the inner core size but makes a geodynamo less likely to operate. Introducing potassium into the core retards inner core growth and provides an additional source of entropy. For our nominal model parameters, a core containing approximate to 400 ppm potassium satisfies the criteria of present-day inner core size, surface heat flux, mantle temperature and cooling rate, and positive core entropy production.We have identified three possibilities that may allow the criteria to be satisfied without potassium in the core. (1) The core thermal conductivity is less than half the generally accepted value of 50 W m(-1) K-1. (2) The core solidus and adiabat are significantly colder and shallower than results from shock experiments and ab initio simulations indicate. (3) The core heat flux has varied by no more than a factor of 2 over Earth history. All models we examined with the correct present-day inner core radius have an inner core age of < 1.5 Gyr; prior to this time the geodynamo was sustained by cooling and radioactive heat production within a completely liquid core

3-Phase Evolution of a Coronal Hole, Part I: 360{\deg} remote sensing and in-situ observations

We investigate the evolution of a well-observed, long-lived, low-latitude coronal hole (CH) over 10 solar rotations in the year 2012. By combining EUV imagery from STEREO-A/B and SDO we are able to track and study the entire evolution of the CH having a continuous 360$\deg$ coverage of the Sun. The remote sensing data are investigated together with in-situ solar wind plasma and magnetic field measurements from STEREO-A/B, ACE and WIND. From this we obtain how different evolutionary states of the CH as observed in the solar atmosphere (changes in EUV intensity and area) affect the properties of the associated high-speed stream measured at $1$AU. Most distinctly pronounced for the CH area, three development phases are derived: a) growing, b) maximum, and c) decaying phase. During these phases the CH area a) increases over a duration of around three months from about $1 \cdot 10^{10} \mathrm{km}^{2}$ to $6 \cdot 10^{10} \mathrm{km}^{2}$, b) keeps a rather constant area for about one month of $> 9 \cdot 10^{10} \mathrm{km}^{2}$, and c) finally decreases in the following three months below $1 \cdot 10^{10} \mathrm{km}^{2}$ until the CH cannot be identified anymore. The three phases manifest themselves also in the EUV intensity and in in-situ measured solar wind proton bulk velocity. Interestingly, the three phases are related to a different range in solar wind speed variations and we find for the growing phase a range of $460-600$~km~s$^{-1}$, for the maximum phase $600-720$~km~s$^{-1}$, and for the decaying phase a more irregular behavior connected to slow and fast solar wind speed of $350-550$~km~s$^{-1}$.Comment: Accepted for publication in Ap

Six supersoft X-ray binaries: system parameters and twin-jet outflows

A comparison is made between the properties of CAL 83, CAL 87, RX J0513.9-6951, 1E 0035.4-7230 (SMC 13), RX J0019.8+2156, and RX J0925.7-4758, all supersoft X-ray binaries. Spectra with the same resolution and wavelength coverage of these systems are compared and contrasted. Some new photometry is also presented. The equivalent widths of the principal emission lines of H and He II differ by more than an order of magnitude among these sources, although those of the highest ionization lines (e.g. O VI) are very similar. In individual systems, the velocity curves derived from various ions often differ in phasing and amplitude, but those whose phasing is consistent with the light curves (implying the lines are formed near the compact star) give masses of $\sim 1.2M_{\odot}$ and $\sim 0.5M_{\odot}$ for the degenerate and mass-losing stars, respectively. This finding is in conflict with currently prevailing theoretical models for supersoft binaries. The three highest luminosity sources show evidence of "jet" outflows, with velocities of $\sim 1-4 \times10^3 km/s$. In CAL 83 the shape of the He II 4686\AA profile continues to show evidence that these jets may precess with a period of $\sim 69$ days.Comment: 27 pages including 5 tables, plus 6 figures. To appear in Ap

Imaging the Earth's Interior: the Angular Distribution of Terrestrial Neutrinos

Decays of radionuclides throughout the Earth's interior produce geothermal heat, but also are a source of antineutrinos. The (angle-integrated) geoneutrino flux places an integral constraint on the terrestrial radionuclide distribution. In this paper, we calculate the angular distribution of geoneutrinos, which opens a window on the differential radionuclide distribution. We develop the general formalism for the neutrino angular distribution, and we present the inverse transformation which recovers the terrestrial radioisotope distribution given a measurement of the neutrino angular distribution. Thus, geoneutrinos not only allow a means to image the Earth's interior, but offering a direct measure of the radioactive Earth, both (1) revealing the Earth's inner structure as probed by radionuclides, and (2) allowing for a complete determination of the radioactive heat generation as a function of radius. We present the geoneutrino angular distribution for the favored Earth model which has been used to calculate geoneutrino flux. In this model the neutrino generation is dominated by decays in the Earth's mantle and crust; this leads to a very ``peripheral'' angular distribution, in which 2/3 of the neutrinos come from angles > 60 degrees away from the downward vertical. We note the possibility of that the Earth's core contains potassium; different geophysical predictions lead to strongly varying, and hence distinguishable, central intensities (< 30 degrees from the downward vertical). Other uncertainties in the models, and prospects for observation of the geoneutrino angular distribution, are briefly discussed. We conclude by urging the development and construction of antineutrino experiments with angular sensitivity. (Abstract abridged.)Comment: 25 pages, RevTeX, 7 figures. Comments welcom