Pharmacokinetic individualisation of zidovudine therapy. Current state of pharmacokinetic-pharmacodynamic relationships

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Antiretrovirale geneesmiddelen in de pijplijn

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Antiretroviral drugs and the central nervous system

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Clinical relevant drug interactions with antiretroviral agents

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No drug-drug interaction between nelfinavir or indinavir and mefloquine in HIV-1-infected patients

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Penetration of 3'-amino-3'deoxythymidine, a cytotoxic metabolite of zidovudine, into the cerebrospinal fluid of HIV-1-infected patients

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HIV-1 RNA levels in the cerebrospinal fluid may increase owing to damage to the blood-brain barrier

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Enhanced penetration of indinavir in cerebrospinal fluid and semen after the addition of low-dose ritonavir

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Low plasma concentrations of indinavir are related to virological treatment failure in HIV-1-infected patients on indinavir-containing triple therapy

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