Circular 20

Since fanning in Alaska first began and especially since dairy farming became the primary agricultural industry, there has existed a need for hardy legumes which would survive Alaska winters and produce satisfactory yields of high quality forage. To meet this need hundreds of legume species and strains have been introduced during the past 40 or more years. Almost all have lacked the necessary hardiness or have not been satisfactory agronomically. The release of Alaskland red clover in the spring of 1953 is the first time a hardy legume has been made available to growers in Alaska.Cooperating with the United States Department of Agriculture, Agricultural Research Administratio

Can the nuclear symmetry potential at supra-saturation densities be negative?

In the framework of an Isospin-dependent Boltzmann-Uehling-Uhlenbeck (IBUU) transport model, for the central $^{197}$Au+$^{197}$Au reaction at an incident beam energy of 400 MeV/nucleon, effect of nuclear symmetry potential at supra-saturation densities on the pre-equilibrium clusters emission is studied. It is found that for the positive symmetry potential at supra-saturation densities the neutron to proton ratio of lighter clusters with mass number $A\leq3$ ($(n/p)_{A\leq3}$) is larger than that of the weighter clusters with mass number $A>3$ ($(n/p)_{A>3}$), whereas for the negative symmetry potential at supra-saturation densities the $(n/p)_{A\leq3}$ is \emph{smaller} than that of the $(n/p)_{A>3}$. This may be considered as a probe of the negative symmetry potential at supra-saturation densities.Comment: 5 pages, 3 figures, 1 table, to be publishe

Heterotopia in Networked Learning: Beyond the Shadow Side of Participation in Learning Communities

As it has evolved, networked learning (NL) has come to emphasise the importance of the collaborative learning aspects and possibilities of online learning. The importance assumed for 'collaboration based' forms of participation within NL has almost become ubiquitous and is frequently seen as an unquestionable good aspect - a utopian view of participation which does not acknowledge the 'shadow side' of participation in learning. In the paper we examine some of the darker sides of collaborative participation which in its extreme manifestations can be experienced as normative and, we suggest, a form of tyranny of the dominant and which instead of having a liberating effect, reinforces a form of oppression and control. We argue this is most likely to be the case in the absence of reflexivity and understanding of different ways and approaches to participation. We go on to suggest an alternative and potentially more productive perspective which, after Foucault, is a heterotopian one. A perspective that acknowledges and assumes disruption and which disturbs our customary notion of ourselves. Participation in heterotopian spaces is disturbing and ambiguous, but it offers a space in which to imagine, to desire and act differently

Towards optimized suppression of dephasing in systems subject to pulse timing constraints

We investigate the effectiveness of different dynamical decoupling protocols for storage of a single qubit in the presence of a purely dephasing bosonic bath, with emphasis on comparing quantum coherence preservation under uniform vs. non-uniform delay times between pulses. In the limit of instantaneous bit-flip pulses, this is accomplished by establishing a new representation of the controlled qubit evolution, where the resulting decoherence behaviour is directly expressed in terms of the free evolution. Simple analytical expressions are given to approximate the long- and short- term coherence behaviour for both ohmic and supra-ohmic environments. We focus on systems with physical constraints on achievable time delays, with emphasis on pure dephasing of excitonic qubits in quantum dots. Our analysis shows that little advantage of high-level decoupling schemes based on concatenated or optimal design is to be expected if operational constraints prevent pulses to be applied sufficiently fast. In such constrained scenarios, we demonstrate how simple modifications of repeated periodic echo protocols can offer significantly improved coherence preservation in realistic parameter regimes.Comment: 13 figures,1 tabl

Effect of Photobiomodulation on Vinblastine-Poisoned Murine HERS Cells

Objective: The aim of this study was to investigate the effect of near-infrared (NIR) photobiomodulation on the proliferation and glutathione levels in murine Hertwig\u27s epithelial root sheath (HERS) cells after poisoning with vinblastine. Background: Photobiomodulation has been shown to improve wound healing in a number of animal models. There have been no studies on the effect of photobiomodulation on cancer-related chemotherapy injury to the cells that initiate tooth root growth. Materials and Methods: Control groups consisted of murine HERS cells without vinblastine (VB−) and cells with vinblastine at 10, 20, and 30 ng/mL (VB10, VB20, and VB30). Experimental groups consisted of these same groups with light therapy (VB-L, VB10L, VB20L, and VB30L). The cells were exposed to vinblastine for 1 h. Photobiomodulation consisted of a 75-cm2 gallium-aluminum-arsenide light-emitting diode (LED) array at an energy density of 12.8 J/cm2, delivered with 50 mW/cm2 power over 256 s. Results: Vinblastine alone significantly decreased HERS cell proliferation and glutathione levels at all concentrations (VB10 [−55%, p \u3c 1.0 × 10−8]; VB20 [−72%, p \u3c 1.0 × 10−9]; VB30 [−80%, p \u3c 1.0 × 10−10]; and VB10 [−36%, p \u3c 0.0001]; VB20 [−49%, p \u3c 1.0 × 10−6]; VB30 [−53%, p \u3c 1.0 × 10−7] respectively). Photobiomodulation significantly increased cell proliferation at all levels of vinblastine exposure (VB10L [+50%, p \u3c 0.0001]; VB20L [+45%, p \u3c 0.05]; VB30 [+39%, p \u3c 0.05]) but not of the control (+22%, p  = 0.063). The photobiomodulation significantly increased glutathione production in all concentrations of vinblastine except 20 ng/mL (VB10L [+39%, p = 0.007]; VB20L [+19%, p = 0.087]; VB30 [+14%, p = 0.025]) and the control (+12%, p = 0.13). Conclusions: Photobiomodulation demonstrated an improvement in proliferation and glutathione levels in vinblastine-poisoned murine HERS cells

Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor

Background The transition from exponential to stationary phase in Streptomyces coelicolor is accompanied by a major metabolic switch and results in a strong activation of secondary metabolism. Here we have explored the underlying reorganization of the metabolome by combining computational predictions based on constraint-based modeling and detailed transcriptomics time course observations. Results We reconstructed the stoichiometric matrix of S. coelicolor, including the major antibiotic biosynthesis pathways, and performed flux balance analysis to predict flux changes that occur when the cell switches from biomass to antibiotic production. We defined the model input based on observed fermenter culture data and used a dynamically varying objective function to represent the metabolic switch. The predicted fluxes of many genes show highly significant correlation to the time series of the corresponding gene expression data. Individual mispredictions identify novel links between antibiotic production and primary metabolism. Conclusion Our results show the usefulness of constraint-based modeling for providing a detailed interpretation of time course gene expression data

Effect of matrix parameters on mesoporous matrix based quantum computation

We present a solid state implementation of quantum computation, which improves previously proposed optically driven schemes. Our proposal is based on vertical arrays of quantum dots embedded in a mesoporous material which can be fabricated with present technology. We study the feasibility of performing quantum computation with different mesoporous matrices. We analyse which matrix materials ensure that each individual stack of quantum dots can be considered isolated from the rest of the ensemble-a key requirement of our scheme. This requirement is satisfied for all matrix materials for feasible structure parameters and GaN/AlN based quantum dots. We also show that one dimensional ensembles substantially improve performances, even of CdSe/CdS based quantum dots