Bis(2-amino-6-methyl­pyridinium) tris­(pyridine-2,6-dicarboxyl­ato)zirconate(IV) dihydrate

In the title compound, (C6H9N2)2[Zr(C7H3NO4)3]·2H2O, the ZrIV atom is nine-coordinated by three pyridine-2,6-dicarboxyl­ate ligands in a distorted tricapped trigonal–prismatic ZrN3O6 environment. The crystal packing is stabilized by inter­molecular N—H⋯O and O—H⋯O hydrogen bonds

Benzene-1,3-diammonium bis­(pyridine-2,6-dicarboxyl­ato-κ3 O 2,N,O 6)cobaltate(II) penta­hydrate

In the title compound, (C6H10N2)[Co(C7H3NO4)2]·5H2O, the CoII ion is six-coordinated in an N2O4 environment by two pyridine-2,6-dicarboxyl­ate (pydc) ligands, having a distorted octa­hedral geometry. The crystal packing is stabilized by inter­molecular N—H⋯O, O—H⋯O and weak C—H⋯O hydrogen bonds. There are also π–π inter­actions between the pyridine rings of the pydc ligands and between the pydc ligands and the benzene-1,3-diammonium cations, with centroid–centroid distances of 3.4575 (15) and 3.7521 (15) Å

Bis(propane-1,2-diammonium) benzene-1,2,4,5-tetra­carboxyl­ate dihydrate

In the crystal of the title hydrated molecular salt, 2C3H12N2 2+·C10H2O8 4−·2H2O, the packing is stabilized by extensive N—H⋯O and O—H⋯O hydrogen-bonding inter­actions involving all three species, forming a supra­molecular three-dimensional structure. The tetraanion is generated by inversion

Lemon Juice as a Natural Catalyse for Synthesis of Shiff’s base: A Green Chemistry Approach

The advantages of the use of natural catalysts are eco-friendly, inexpensive, high yields, nonhazardous and short reaction times. The utilization of green chemistry techniques is the elimination of solvents during chemical processes or the replacement of hazardous solvents with environmentally friendly solvents. Green chemistry has used for the synthesis of Schiff bases. Synthesis of Schiff base is carried out the mixture of aldehyde (or ketone) and amine in organic medium with or without an acid catalyst. He presents study Uses Lemon juice as a natural and eco-friendly catalyst in the green chemistry investigated. The synthesized product was characterized by its physical properties, melting point, TLC and then subjected to the in vitro antibacterial activities against gram-positive and gram-negative strains of microbes

Benzene-1,3-diammonium bis­(pyridine-2,6-dicarboxyl­ato)nickelate(II) penta­hydrate

In the title compound, (C6H10N2)[Ni(C7H3NO4)2]·5H2O, the NiII ion is six-coordinated by two N and four O atoms from two pyridine-2,6-dicarboxyl­ate ligands in a distorted octa­hedral fashion. The crystal packing is stabilized by inter­molecular O—H⋯O and N—H⋯O and weak C—H⋯O hydrogen bonds and π–π inter­actions [centroid–centroid distances = 3.4669 (19) and 3.764 (2) Å]

Poly[aqua­(dimethyl sulfoxide)(μ4-pyridine-2,5-dicarboxyl­ato)calcium(II)]

In the polymeric title compound, [Ca(C7H3NO4)(H2O)(C2H6OS)]n, the CaII ion is coordinated in a distorted penta­gonal–bipyramidal CdNO6 geometry. The crystal packing is stabilized by O—H⋯O hydrogen bonds and π–π stacking inter­actions between the aromatic rings of pyridine-2,5-dicarb­oxy­late with centroid–centroid distances of 3.6166 (13) Å

Poly[tri-μ2-aqua-(μ3-pyridine-2,4-dicarboxyl­ato-κ4 N,O 2:O 2:O 2′)barium]

In the polymeric title compound, [Ba(C7H3NO4)(H2O)3]n, the BaII ion is ten-coordinated in an NO9 environment by one N atom and three O atoms from three pyridine-2,4-dicarboxyl­ate (pydc) ligands and six water mol­ecules. The μ3-pydc ligands and the bridging water mol­ecules connect the Ba atoms into a layer parallel to (100). The crystal packing is stabilized by O—H⋯O and C—H⋯O hydrogen bonds

Synthesis, structural characterization and biological activity of Cu(II), Co(II) and Ni(II) complexes derived from 2-(thiazol-2-ylimino)thiazolidin-4-one ligand

A novel series of metal complexes of 2-(thiazol-2-ylimino) thiazolidin-4-one ligand were prepared; the corresponding ligand was synthesized from reaction 2-Chloro-N-(thiazol-2-yl) acetamide with ammonium thiocyanate. The complexes are characterized by FTIR, UV-Vis, molar conductance and mass spectroscopy. The low molar conductance values indicate that the complexes are non-electrolytes.Spectroscopic studies confirmed that the ligand bonded to the metals through the sulphur atoms. Coordination number of copper and nickel complexes is four with square planar geometry, while the cobalt complex has octahedral geometry.In vitro antibacterial activity of ligand and its metal complexes was evaluated using well diffusion method and compared to the standard drug (tetracycline). The antibacterial activitywas examined against Escherichia coli, and pseudomonas aeruginosa, as gram negative bacteria and Staphylococcus aureus as gram positive bacteria. It was found that Nickel complex has the highest antibacterial activity among the synthesized compounds with Zone inhibition diameter in the range 25-29 mm

Using of Naproxen drug for novel synthesis of 4-thiazolidinone derivatives and application of these drugs as no steroidal anti-inflammatory drug (NSAIDs) and as anti-epileptic agent

Non-steroidal anti-inflammatory drugs (NSAIDs) are now one of the most frequent drugs used in treatment of pain, inflammation and fever. In this study the aim is the synthesis of derivatives of 4-Tiazolidinon from naproxen with the possible anti-pain effects, and the main purpose of providing these derivatives is to achieve a compound with more anti-pain power and less side effects in comparison with applied drugs in clinics. Synthesis of these derivatives is done on chloride in presence of a group of new liquids like recyclable ionic liquids choline chloride, which the main advantages of these ionic liquids are the cheapness, availability, being non-toxic, and easy recyclability. This reaction was done in four stages. All the structures were verified by using data of spectrum testing, 1H-NMR, FT-IR

Poly[propane-1,3-diammonium [cuprate(II)-bis­(μ2-pyridine-2,3-dicarboxyl­ato)] trihydrate]

The title polymeric compound {(C3H12N2)[Cu(C7H3NO4)2]·3H2O}n or {(pnH2)[Cu(py-2,3-dc)2]·3H2O}n (pn is propane-1,3-diamine and py-2,3-dcH2 is pyridine-2,3-dicarboxylic acid), was synthesized by reaction of copper(II) chloride dihydrate with a proton-transfer compound, propane-1,3-diammonium pyridine-2,3-dicarboxyl­ate or (pnH2)(py-2,3-dc), in aqueous solution. The anion is a six-coordinate complex (site symmetry ), with a distorted octa­hedral geometry around CuII, consisting of two bidentate pyridine-2,3-dicarboxyl­ate groups and two O atoms of bridging ligands from (py-2,3-dc)2− fragments, which are located in trans positions. The (pnH2)2+ cation is disordered over two sites by the center of inversion. Inter­molecular hydrogen bonds, π–π [centroid–centroid distances of 3.539 (3) Å] and C—O⋯π stacking inter­actions [O⋯Cg = 3.240 (5) Å; Cg is the center of the pyridine ring], connect the various components into a supra­molecular structure