On the Yang - Mills Gravity

The parallel between Yang-Mills theory and General Relativity isan attractive topic that motivated a lot of interestingresearches. Various versions of the gauge theory of gravity wereproposed which provided a deep understanding of such basisconcepts as the geometry of space-time, the connection betweensymmetry and dynamics. In this work we consider the problem ofinteraction between intrinsic degrees of freedom of particles withthe Lorentz gauge field solution that has the same singularfeature as for the Schwarzschild solution of General Relativity.The effective potential for a particle in the Schwarzschild-likeLorentz gauge field was investigated in comparison with Einsteinand Newtonian theories of gravity. The equations of motion forparticles allows planar motions that can be solved numerically. Wehave shown that there exit the Kepler-like orbits which correspondto certain sets of parameters and initial conditions. The obtainedresults can be regarded as an experimental evidence for theexistence of the "internal Lorentz symmetry" of point particlesthat is analogue to internal unitary symmetries

EAGLE—A Scalable Query Processing Engine for Linked Sensor Data

Recently, many approaches have been proposed to manage sensor data using semantic web technologies for effective heterogeneous data integration. However, our empirical observations revealed that these solutions primarily focused on semantic relationships and unfortunately paid less attention to spatio–temporal correlations. Most semantic approaches do not have spatio–temporal support. Some of them have attempted to provide full spatio–temporal support, but have poor performance for complex spatio–temporal aggregate queries. In addition, while the volume of sensor data is rapidly growing, the challenge of querying and managing the massive volumes of data generated by sensing devices still remains unsolved. In this article, we introduce EAGLE, a spatio–temporal query engine for querying sensor data based on the linked data model. The ultimate goal of EAGLE is to provide an elastic and scalable system which allows fast searching and analysis with respect to the relationships of space, time and semantics in sensor data. We also extend SPARQL with a set of new query operators in order to support spatio–temporal computing in the linked sensor data context.EC/H2020/732679/EU/ACTivating InnoVative IoT smart living environments for AGEing well/ACTIVAGEEC/H2020/661180/EU/A Scalable and Elastic Platform for Near-Realtime Analytics for The Graph of Everything/SMARTE

The Schema Editor of OpenIoT for Semantic Sensor Networks

Ontologies provide conceptual abstractions over data, in domains such as the Internet of Things, in a way that sensor data can be harvested and interpreted by people and applications. The Semantic Sensor Network (SSN) ontology is the de-facto standard for semantic representation of sensor observations and metadata, and it is used at the core of the open source platform for the Internet of Things, OpenIoT. In this paper we present a Schema Editor that provides an intuitive web interface for defining new types of sensors, and concrete instances of them, using the SSN ontology as the core model. This editor is fully integrated with the OpenIoT platform for generating virtual sensor descriptions and automating their semantic annotation and registration process

Robust and Hierarchical Stop Discovery in Sparse and Diverse Trajectories

The advance of GPS tracking technique brings a large amount of trajectory data. To better understand such mobility data, semantic models like “stop/move” (or inferring “activity”, “transportation mode”) recently become a hot topic for trajectory data analysis. Stops are important parts of tra- jectories, such as “working at office”, “shopping in a mall”, “waiting for the bus”. There are several methods such as velocity, clustering, density algorithms being designed to discover stops. However, existing works focus on well-defined trajectories like movement of vehicle and taxi, not working well for heterogeneous cases like diverse and sparse trajectories. On the contrary, our paper addresses three main challenges: (1) provide a robust clustering-based method to discover stops; (2) discover both shared stops and personalized stops, where shared stops are the common places where many trajectories pass and stay for a while (e.g. shopping mall), whilst personalized stops are individual places where user stays for his/her own purpose (e.g. home, office); (3) further build stop hierarchy (e.g. a big stop like EPFL campus and a small stop like an office building). We evaluate our approach with several diverse and spare real-life GPS data, compare it with other methods, and show its better data abstraction on trajectory

Green synthesis and crystal structure of 3-(benzo-thia-zol-2-yl)thio-phene.

The title compound, C11H7NS2, was prepared in high yield (87%) using a solvent-free microwave-assisted synthesis. The structure shows whole-mol-ecule disorder with occupancies for two orientations (A and B) of 0.4884 (10) and 0.5116 (10), respectively. The thio-phene and benzo-thia-zole rings are almost planar and make dihedral angles of 10.02 (18) and 12.54 (19)° for orientations A and B, respectively. Slipped π-π stacking between the aromatic rings, together with C-H⋯π, C-H⋯S and C-H⋯N inter-actions, result in a herringbone motif in the crystal packing

SOME RESULTS OF AIR MONITORING QUALITY IN HANOI AND ASSESSMENT OF AIR MONITORING METHODS USED IN VIETNAM

Joint Research on Environmental Science and Technology for the Eart

Concomitant Bacteremia in Adults With Severe Falciparum Malaria.

BackgroundApproximately 6% of children hospitalized with severe falciparum malaria in Africa are also bacteremic. It is therefore recommended that all children with severe malaria should receive broad-spectrum antibiotics in addition to parenteral artesunate. Empirical antibiotics are not recommended currently for adults with severe malaria.MethodsBlood cultures were performed on sequential prospectively studied adult patients with strictly defined severe falciparum malaria admitted to a single referral center in Vietnam between 1991 and 2003.ResultsIn 845 Vietnamese adults with severe falciparum malaria admission blood cultures were positive in 9 (1.07%: 95% confidence interval [CI], .37-1.76%); Staphylococcus aureus in 2, Streptococcus pyogenes in 1, Salmonella Typhi in 3, Non-typhoid Salmonella in 1, Klebsiella pneumoniae in 1, and Haemophilus influenzae type b in 1. Bacteremic patients presented usually with a combination of jaundice, acute renal failure, and high malaria parasitemia. Four bacteremic patients died compared with 108 (12.9%) of 836 nonbacteremic severe malaria patients (risk ratio, 3.44; 95% CI, 1.62-7.29). In patients with >20% parasitemia the prevalence of concomitant bacteremia was 5.2% (4/76; 95% CI, .2-10.3%) compared with 0.65% (5/769; 0.08-1.2%) in patients with ConclusionsIn contrast to children, the prevalence of concomitant bacteremia in adults with severe malaria is low. Administration of empirical antibiotics, in addition to artesunate, is warranted in the small subgroup of patients with very high parasitemias, emphasizing the importance of quantitative blood smear microscopy assessment, but it is not indicated in most adults with severe falciparum malaria

An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis

Background: Cryptococcal meningitis has high mortality. Flucytosine is a key treatment but is expensive and rarely available. The anti-cancer agent tamoxifen has synergistic anti-cryptococcal activity with amphotericin in vitro. It is off-patent, cheap, and widely available. We performed a trial to determine its therapeutic potential. Methods:Open label randomized controlled trial. Participants received standard care - amphotericin combined with fluconazole for the first two weeks - or standard care plus tamoxifen 300mg/day. The primary end point was Early Fungicidal Activity (EFA) - the rate of yeast clearance from cerebrospinal fluid (CSF). Trial registration https://clinicaltrials.gov/ct2/show/NCT03112031 . Results: 50 patients were enrolled, (median age 34 years, 35 male). Tamoxifen had no effect on EFA (- 0.48log10 colony-forming units/mL/CSF control arm versus -0.49 tamoxifen arm, difference - 0.005log10CFU/ml/day, 95%CI: -0.16, 0.15, P=0.95). Tamoxifen caused QTc prolongation. Conclusion: High dose tamoxifen does not increase the clearance rate of Cryptococcus from CSF. Novel, affordable therapies are needed. Funding:The trial was funded through the Wellcome Trust Asia Programme Vietnam Core Grant 106680 and a Wellcome Trust Intermediate Fellowship to JND grant number WT097147MA