2,176 research outputs found
A new and efficient intelligent collaboration scheme for fashion design
Technology-mediated collaboration process has been extensively studied for over a decade. Most applications with collaboration concepts reported in the literature focus on enhancing efficiency and effectiveness of the decision-making processes in objective and well-structured workflows. However, relatively few previous studies have investigated the applications of collaboration schemes to problems with subjective and unstructured nature. In this paper, we explore a new intelligent collaboration scheme for fashion design which, by nature, relies heavily on human judgment and creativity. Techniques such as multicriteria decision making, fuzzy logic, and artificial neural network (ANN) models are employed. Industrial data sets are used for the analysis. Our experimental results suggest that the proposed scheme exhibits significant improvement over the traditional method in terms of the time–cost effectiveness, and a company interview with design professionals has confirmed its effectiveness and significance
Physical Layer Security in Wireless Ad Hoc Networks Under A Hybrid Full-/Half-Duplex Receiver Deployment Strategy
This paper studies physical layer security in a wireless ad hoc network with
numerous legitimate transmitter-receiver pairs and eavesdroppers. A hybrid
full-/half-duplex receiver deployment strategy is proposed to secure legitimate
transmissions, by letting a fraction of legitimate receivers work in the
full-duplex (FD) mode sending jamming signals to confuse eavesdroppers upon
their information receptions, and letting the other receivers work in the
half-duplex mode just receiving their desired signals. The objective of this
paper is to choose properly the fraction of FD receivers for achieving the
optimal network security performance. Both accurate expressions and tractable
approximations for the connection outage probability and the secrecy outage
probability of an arbitrary legitimate link are derived, based on which the
area secure link number, network-wide secrecy throughput and network-wide
secrecy energy efficiency are optimized respectively. Various insights into the
optimal fraction are further developed and its closed-form expressions are also
derived under perfect self-interference cancellation or in a dense network. It
is concluded that the fraction of FD receivers triggers a non-trivial trade-off
between reliability and secrecy, and the proposed strategy can significantly
enhance the network security performance.Comment: Journal paper, double-column 12 pages, 9 figures, accepted by IEEE
Transactions on Wireless Communications, 201
Immunotherapy for Lung Cancers
Lung cancer is the leading cause of cancer-related deaths worldwide. Although treatment methods in surgery, irradiation, and chemotherapy have improved, prognosis remains unsatisfactory and developing new therapeutic strategies is still an urgent demand. Immunotherapy is a novel therapeutic approach wherein activated immune cells can specifically kill tumor cells by recognition of tumor-associated antigens without damage to normal cells. Several lung cancer vaccines have demonstrated prolonged survival time in phase II and phase III trials, and several clinical trials are under investigation. However, many clinical trials involving cancer vaccination with defined tumor antigens work in only a small number of patients. Cancer immunotherapy is not completely effective in eradicating tumor cells because tumor cells escape from host immune scrutiny. Understanding of the mechanism of immune evasion regulated by tumor cells is required for the development of more effective immunotherapeutic approaches against lung cancer. This paper discusses the identification of tumor antigens in lung cancer, tumor immune escape mechanisms, and clinical vaccine trials in lung cancer
From Biomarker Discovery to Clinical Evaluation for Early Diagnosis of Lung Surgery-Induced Injury
Single‐Step Primary Amine Synthesis on Proton Sensitive Nanofilms to Overcome Its Debye Length Limitations
Sympathetic-correlated c-Fos expression in the neonatal rat spinal cord in vitro
An isolated thoracic spinal cord of the neonatal rat in vitro spontaneously generates sympathetic nerve discharge (SND) at ~25°C, but it fails in SND genesis at ≤ 10°C. Basal levels of the c-Fos expression in the spinal cords incubated at ≤ 10°C and ~25°C were compared to determine the anatomical substrates that might participate in SND genesis. Cells that exhibited c-Fos immunoreactivity were virtually absent in the spinal cords incubated at ≤ 10°C. However, in the spinal cords incubated at ~25°C, c-Fos-positive cells were found in the dorsal laminae, the white matter, lamina X, and the intermediolateral cell column (IML). Cell identities were verified by double labeling of c-Fos with neuron-specific nuclear protein (NeuN), glial fibrillary acidic protein (GFAP), or choline acetyltransferase (ChAT). The c-Fos-positive cells distributed in the white matter and lamina X were NeuN-negative or GFAP-positive and were glial cells. Endogenously active neurons showing c-Fos and NeuN double labeling were scattered in the dorsal laminae and concentrated in the IML. Double labeling of c-Fos and ChAT confirmed the presence of active sympathetic preganglionic neurons (SPNs) in the IML. Suppression of SND genesis by tetrodotoxin (TTX) or mecamylamine (MECA, nicotinic receptor blocker) almost abolished c-Fos expression in dorsal laminae, but only mildly affected c-Fos expression in the SPNs. Therefore, c-Fos expression in some SPNs does not require synaptic activation. Our results suggest that spinal SND genesis is initiated from some spontaneously active SPNs, which are capable of TTX- or MECA-resistant c-Fos expression
Machine learning guided discovery of superconducting calcium borocarbides
Pursuit of superconductivity in light-element systems at ambient pressure is
of great experimental and theoretical interest. In this work, we combine a
machine learning (ML) method with first-principles calculations to efficiently
search for the energetically favorable ternary Ca-B-C compounds. Three new
layered borocarbides (stable CaBC5 and metastable Ca2BC11 and CaB3C3) are
predicted to be phonon-mediated superconductors at ambient pressure. The
hexagonal CaB3C3 possesses the highest Tc of 26.05 K among the three compounds.
The {\sigma}-bonging bands around the Fermi level account for the large
electron-phonon coupling ({\lambda} = 0.980) of hexagonal CaB3C3. The ML-guided
approach opens up a way for greatly accelerating the discovery of new high-Tc
superconductors
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