The Human Right to Science and Foundational Technologies

Feeney et al. (2018) make a valid argument for restrictions on the exclusivity of foundational technologies such as CRISPR. The issue of balancing intellectual property right with access to scientific and technological advancements is certainly not new. In our commentary, we argue that the human right to science offers a more concrete basis for governments to balance their competing commitments in promoting scientific development on the one hand, and ensuring benefit-sharing on the other, in ways that advance social justice under non-ideal conditions

Comparing the prime and subprime mortgage markets

Against the backdrop of news reports on high mortgage delinquency rates, this article examines recent trends in mortgage lending and compares the prime and subprime markets in particular.Mortgages

Global banking and national regulation: a conference summary

Although banking across national borders has expanded rapidly, banking regulation remains nationally based. As a result, governments and financial institutions face significant challenges when instability arises. At the Chicago Fed’s International Banking Conference, participants explored cross-border banking issues and ways to improve the current system.Banks and banking, International ; Interstate banking

Overview of Legal Systems in the Asia-Pacific Region: Singapore

This article provides a general description of the legal system of Singapore. It further discusses aspects of legal education and legal practice in that country

Overview of Legal Systems in the Asia-Pacific Region: Singapore

This article provides a general description of the legal system of Singapore. It further discusses aspects of legal education and legal practice in that country

Liquid-shaped microlens for scalable production of ultrahigh-resolution OCT microendoscope

Endoscopic optical coherence tomography (OCT) is a valuable tool for providing diagnostic images of internal organs and guiding interventions in real time. Miniaturized OCT endoscopes are essential for imaging small and convoluted luminal organs while minimizing invasiveness. However, current methods for fabricating miniature fiber probes have limited ability to correct optical aberrations, leading to suboptimal imaging performance. In this study, we introduce a new paradigm of liquid shaping technique for the rapid and scalable fabrication of ultrathin and high-performance OCT microendoscopes suitable for minimally invasive clinical applications. This technique enables the flexible customization of freeform microlenses with sub-nanometer optical surface roughness by regulating the minimum energy state of curable optical liquid on a wettability-modified substrate and precisely controlling the liquid volume and physical boundary on a substrate. Using this technique, we simultaneously fabricated 800-nm OCT microendoscopes with a diameter of approximately 0.6 mm and evaluated their ultrahigh-resolution imaging performance in the esophagus of rats and the aorta and brain of mice.Comment: 42 pages, 7 figures in the main tex

Floristic quality assessment and ecosystem analysis of the Duncan Bay nature Preserve, Cheboygan County, Michigan

Field Botany of Northern MichiganHere we provide a comprehensive list of flora found within the Duncan Bay Nature Preserve, for which we report a Native Floristic Quality Index number of 69.3. Furthermore, we provide recommendations for site management including a geolocated list of alien and invasive species with potential removal suggestions, details of a geolocated population of Michigan’s threatened state wildflower Iris lacustris, a detailed walking-trail plan including a proposed parking lot location, and informational signs at key locations.http://deepblue.lib.umich.edu/bitstream/2027.42/116389/1/Buchanan_Coy_Ho_Jones_Marshall_McGuffie_Skrzypek_Zettell_2015.pd