584 research outputs found
Copper(II)- and gold(III)-mediated cyclization of a thiourea to a substituted 2-aminobenzothiazole
Benzothiazole derivatives are a class of privileged molecules due to their biological activity and pharmaceutical applications. One route to these molecules is via intramolecular cyclization of thioureas to form substituted 2-aminobenzothiazoles, but this often requires harsh conditions or employs expensive metal catalysts. Herein, the copper(II)- and gold(III)-mediated cyclizations of thioureas to substituted 2-aminobenzothiazoles are reported. The single-crystal X-ray structures of the thiourea N-(3-methoxyphenyl)-N\u27- (pyridin-2-yl)thiourea, C13H13N3OS, and the intermediate metal complexes aquabis[5-methoxy-N-(pyridin-2-yl-κN)-1,3-benzothiazol-2-amine-κN3]copper(II) dinitrate, [Cu(C13H11N3OS)2(H2O)](NO3)2, and bis{2-[(5-methoxy-1,3-benzothiazol- 2-yl)amino]pyridin-1-ium} dichloridogold(I) chloride monohydrate, (C13H12N3OS)2[AuCl2]Cl⋅H2O, are reported. The copper complex exhibits a distorted trigonal–bipyramidal geometry, with direct metal-to-benzothiazoleligand coordination, while the gold complex is a salt containing the protonated uncoordinated benzothiazole, and offers evidence that metal reduction (in this case, AuIII to AuI) is required for the cyclization to proceed. As such, this study provides further mechanistic insight into the role of the metal cations in these transformations
Astrophysical Bounds on Global Strings
Global topological defects produce nonzero stress-energy throughout
spacetime, and as a result can have observable gravitational influence on
surrounding matter. Gravitational effects of global strings are used to place
bounds on their cosmic abundance. The minimum separation between global strings
is estimated by considering the defects' contribution to the cosmological
energy density. More rigorous constraints on the abundance of global strings
are constructed by examining the tidal forces such defects will have on
observable astrophysical systems. The small number of observed tidally
disrupted systems indicates there can be very few of these objects in the
observable universe.Comment: 14 pages, REVTe
Second Order Dissipative Fluid Dynamics for Ultra-Relativistic Nuclear Collisions
The M\"uller-Israel-Stewart second order theory of relativistic imperfect
fluids based on Grad's moment method is used to study the expansion of hot
matter produced in ultra-relativistic heavy ion collisions. The temperature
evolution is investigated in the framework of the Bjorken boost-invariant
scaling limit. The results of these second-order theories are compared to those
of first-order theories due to Eckart and to Landau and Lifshitz and those of
zeroth order (perfect fluid) due to Euler.Comment: 5 pages, 4 figures, size of y-axis tick marks for Figs. 3 and 4 fixe
Supramolecular self-associating amphiphiles: determination of molecular self-association properties and calculation of critical micelle concentration using a high-throughput, optical density based methodology
Supramolecular self-associating amphiphiles are a class of amphiphilic salt, the anionic component of which is 'frustrated' in nature, meaning multiple hydrogen bonding modes can be accessed simultaneously. Here we derive critical micelle concentration values for four supramolecular self-associating amphiphiles using the standard pendant drop approach and present a new high-throughput, optical density measurement based methodology, to enable the estimation of critical micelle concentrations over multiple temperatures. In addition, we characterise the low-level hydrogen bonded self-association events in the solid state, through single crystal X-ray diffraction, and in polar organic DMSO-d(6) solutions using a combination of H-1 NMR techniques. Moving into aqueous ethanol solutions (EtOH/H2O or EtOH/D2O (1 : 19 v/v)), we also show these amphiphilic compounds to form higher-order self-associated species through a combination of H-1 NMR, dynamic light scattering and zeta potential studies
Baryon inhomogeneity generation via cosmic strings at QCD scale and its effects on nucleosynthesis
We have earlier shown that cosmic strings moving through the plasma at the
time of a first order quark-hadron transition in the early universe can
generate large scale baryon inhomogeneities. In this paper, we calculate
detailed structure of these inhomogeneities at the quark-hadron transition. Our
calculations show that the inhomogeneities generated by cosmic string wakes can
strongly affect nucleosynthesis calculations. A comparison with observational
data suggests that such baryon inhomogeneities should not have existed at the
nucleosynthesis epoch. If this disagreement holds with more accurate
observations, then it will lead to the conclusions that cosmic string formation
scales above GeV may not be consistent with nucleosynthesis
and CMBR observations. Alternatively, some other input in our calculation
should be constrained, for example, if the average string velocity remains
sufficiently small so that significant density perturbations are never produced
at the QCD scale, or if strings move ultra-relativistically so that string
wakes are very thin, trapping negligible amount of baryons. Finally, if
quark-hadron transition is not of first order then our calculations do not
apply.Comment: 24 pages, 5 figures, minor changes, version to appear in Phys. Rev.
Renormalization Group Approach to Causal Viscous Cosmological Models
The renormalization group method is applied to the study of homogeneous and
flat Friedmann-Robertson-Walker type Universes, filled with a causal bulk
viscous cosmological fluid. The starting point of the study is the
consideration of the scaling properties of the gravitational field equations,
of the causal evolution equation of the bulk viscous pressure and of the
equations of state. The requirement of scale invariance imposes strong
constraints on the temporal evolution of the bulk viscosity coefficient,
temperature and relaxation time, thus leading to the possibility of obtaining
the bulk viscosity coefficient-energy density dependence. For a cosmological
model with bulk viscosity coefficient proportional to the Hubble parameter, we
perform the analysis of the renormalization group flow around the scale
invariant fixed point, therefore obtaining the long time behavior of the scale
factor.Comment: 19 pages. RevTeX4. Revised version. Accepted in Classical and Quantum
Gravit
Cosmic string induced sheet like baryon inhomogeneities at quark-hadron transition
Cosmic strings moving through matter produce wakes where density is higher
than the background density. We investigate the effects of such wakes occurring
at the time of a first order quark-hadron transition in the early universe and
show that they can lead to separation of quark-gluon plasma phase in the wake
region, while the region outside the wake converts to the hadronic phase.
Moving interfaces then trap large baryon densities in sheet like regions which
can extend across the entire horizon. Typical separation between such sheets,
at formation, is of the order of a km. Regions of baryon inhomogeneity of this
nature, i.e. having a planar geometry, and separated by such large distance
scales, appear to be well suited for the recent models of inhomogeneous
nucleosynthesis to reconcile with the large baryon to photon ratio implied by
the recent measurements of the cosmic microwave background power spectrum.Comment: 8 pages, 3 figure
Viscous Bianchi type I universes in brane cosmology
We consider the dynamics of a viscous cosmological fluid in the generalized
Randall-Sundrum model for an anisotropic, Bianchi type I brane. To describe the
dissipative effects we use the Israel-Hiscock-Stewart full causal thermodynamic
theory. By assuming that the matter on the brane obeys a linear barotropic
equation of state, and the bulk viscous pressure has a power law dependence on
the energy density, the general solution of the field equations can be obtained
in an exact parametric form. The obtained solutions describe generally a
non-inflationary brane world. In the large time limit the brane Universe
isotropizes, ending in an isotropic and homogeneous state. The evolution of the
temperature and of the comoving entropy of the Universe is also considered, and
it is shown that due to the viscous dissipative processes a large amount of
entropy is created in the early stages of evolution of the brane world.Comment: 13 pages, 5 figures, to appear in Class. Quantum Gra
The perilous state of seagrass in the British Isles
Seagrass ecosystems face widespread threat from reduced water quality, coastal development and poor land use. In recent decades, their distribution has declined rapidly, and in the British Isles, this loss is thought to have been extensive. Given increasing knowledge of how these ecosystems support fisheries production, the understanding of their potential rapid loss, and the difficulty in restoring them, it is vital we develop an understanding of the risks they are under, so that management actions can be developed accordingly. Developing an understanding of their environmental status and condition is therefore critical to their long-term management. This study provided, to our knowledge, the first examination of the environmental health of seagrass meadows around the British Isles. This study used a bioindicator approach and involved collecting data on seagrass density and morphology alongside analysis of leaf biochemistry. Our study provides, to the best of our knowledge, the first strong quantitative evidence that seagrass meadows of the British Isles are mostly in poor condition in comparison with global averages, with tissue nitrogen levels 75% higher than global values. Such poor status places their long-term resilience in doubt. Elemental nutrient concentrations and morphological change suggest conditions of excess nitrogen and probable low light, placing many of the meadows sampled in a perilous state, although others, situated away from human populations were perceived to be healthy. Although some sites were of a high environmental health, all sites were considered at risk from anthropogenic impacts, particularly poor water quality and boating-based disturbances. The findings of this study provide a warning of the need to take action, with respect to water quality and disturbance, to prevent the further loss and degradation of these systems across the British Isles
High-frequency monitoring of nitrogen and phosphorus response in three rural catchments to the end of the 2011–2012 drought in England
This paper uses high-frequency bankside measurements from three catchments selected as part of the UK government-funded Demonstration Test Catchments (DTC) project. We compare the hydrological and hydrochemical patterns during the water year 2011–2012 from the Wylye tributary of the River Avon with mixed land use, the Blackwater tributary of the River Wensum with arable land use and the Newby Beck tributary of the River Eden with grassland land use. The beginning of the hydrological year was unusually dry and all three catchments were in states of drought. A sudden change to a wet summer occurred in April 2012 when a heavy rainfall event affected all three catchments. The year-long time series and the individual storm responses captured by in situ nutrient measurements of nitrate and phosphorus (total phosphorus and total reactive phosphorus) concentrations at each site reveal different pollutant sources and pathways operating in each catchment. Large storm-induced nutrient transfers of nitrogen and or phosphorus to each stream were recorded at all three sites during the late April rainfall event. Hysteresis loops suggested transport-limited delivery of nitrate in the Blackwater and of total phosphorus in the Wylye and Newby Beck, which was thought to be exacerbated by the dry antecedent conditions prior to the storm. The high rate of nutrient transport in each system highlights the scale of the challenges faced by environmental managers when designing mitigation measures to reduce the flux of nutrients to rivers from diffuse agricultural sources. It also highlights the scale of the challenge in adapting to future extreme weather events under a changing climate
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