17 research outputs found
Did FDI replace the role of the government, or the government supported the FDI in the process of industrial development? : a case study of the Thai textile industry
Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 1996.Includes bibliographical references (leaves 118-124).by Yayoi Hirose.M.C.P
Dorsamin-A’s, Glycerolipids Carrying a Dehydrophenylalanine Ester Moiety from the Seed-Eating Larvae of the Bruchid Beetle <i>Bruchidius dorsalis</i>
Using a TLC autographic assay for
radical-scavenging activity with
the ABTS radical, the presence of lipophilic antioxidants in the larvae
of the wild bruchid seed beetle <i>Bruchidius dorsalis</i> was detected. Assay-guided fractionation of the CHCl<sub>3</sub>-soluble fraction of the larvae resulted in the isolation of new
glycerolipids, designated dorsamin-A763, -A737, -A765, -A739, and
-A767, comprising 1,2-diacyl-<i>sn</i>-glycero-3-dehydrophenylalanine
ester structural units. The ABTS radical scavenging activity of the
dorsamin-A’s was comparable with or stronger than that of Trolox
Generation and characterization of severe combined immunodeficiency rats.
重症免疫不全SCIDラットの作製 : ヒトiPS細胞、がん細胞、肝細胞をラット体内で培養することに成功. 京都大学プレスリリース. 2012-09-14.Severe combined immunodeficiency (SCID) mice, the most widely used animal model of DNA-PKcs (Prkdc) deficiency, have contributed enormously to our understanding of immunodeficiency, lymphocyte development, and DNA-repair mechanisms, and they are ideal hosts for allogeneic and xenogeneic tissue transplantation. Here, we use zinc-finger nucleases to generate rats that lack either the Prkdc gene (SCID) or the Prkdc and Il2rg genes (referred to as F344-scid gamma [FSG] rats). SCID rats show several phenotypic differences from SCID mice, including growth retardation, premature senescence, and a more severe immunodeficiency without "leaky" phenotypes. Double-knockout FSG rats show an even more immunocompromised phenotype, such as the abolishment of natural killer cells. Finally, xenotransplantation of human induced pluripotent stem cells, ovarian cancer cells, and hepatocytes shows that SCID and FSG rats can act as hosts for xenogeneic tissue grafts and stem cell transplantation and may be useful for preclinical testing of new drugs