Therapeutic Approaches to Aggressive Carcinomas Based on a Novel VEGF/Neuropilin Autocrine Pathway

Summary: Autocrine VEGF signaling in tumor cells contributes to de-differentiation and function of tumor initiating/stem cells. NRP2 is the nexus of a signaling pathway that promotes de-differentiation and sustains tumor initiating/stem sells. Anti-NRP2 therapy is worth pursuing, especially for high-grade cancers. Therapeutic Abs are available. This presentation was part of the retreat mini-symposium entitled: Biomarker Discovery and Targeted Therapeutics in Cancer

Money Management Knowledge of College Students

This study describes the money management knowledge of college students and identifies the characteristics of students associated with the differences in that knowledge level

Students\u27 Perceptions of Their Education Debt and Its Impact on Life After Graduation

Student loans comprise the primary source of financial aid funding for higher education. But how much do students know about the realities of loan indebtedness? This study evaluates data collected in winter 1996 from 443 graduating seniors at a Midwestem university. Its results diverge somewhat from those of some early studies, yet support other recent research. Many of the surveyed students were reportedly unaware of their total loan indebtedness and payment obligations (over- and underestimating debt payments); borrowed to support a better lifestyle ; and were unable to estimate realistically their post-graduation earnings and ability to meet their repayment obligations. The results suggest a need for greater educating of prospective borrowers and the assumption of a preventive posture on the part of those involved in the lending process

An analysis of RDF view maintenance using Jena

Resource Description Framework is a next generation technique to create web content. This has given rise to the need to develop efficient and effective techniques to manage high volume RDF structures. This paper deals with Semantic Web technologies and presents an analysis of JENA based updation of RDF structures. The view maintenance of RDF structures (varying sizes), i.e. updating RDF structures using views is performed through JENA constructs and performance of insertion and deletion operations is measured. After analysis, Insert operation time was observed to increase proportionally however time remained the same for delete operations performed on the RDF dat

Antimicrobial Activity of N-hexane Extracts of Red Frangipani (Plumeria Rocea)

Antimicrobial assay of n-hexane plant extracts against Escherichia coli and Staphylococcus aureus had been done. Extraction with n-Hexane of the flowers yielded 2,08% of extract, while leaves and stems yielded 3,21% and 2,19% of n-hexane extracts, respectively. The extracts showed different activity against both bioindicators. The leaves extracts showed the strongest activity indicated by wider diameters of inhibition zone, 19,7 mm against E. coli and 13,3 mm against S. aureus at 10% of the extracts' concentration. At the same concentration (10%), the steam and flower extracts showed less inhibitory activities with 11,3 mm and 8,3 mm against E. coli, and 12,0 mm and 11,0 mm against S. aureus. At the lowest concentration of the extracts, the leaves extracts showed the strongest activity against E. coli (14,3 mm) while the steam extracts showed highest inhibitory activity against S. aureus ( 7,7 mm). Based on antimicrobial assay, it was suggested that the leaves extracts demonstrated strongest activity than other extracts. It was assumed that leaves extracts contained more secondary metabolite than flowers and steams, and the leaves have phenol compounds which are not present in other extracts

Varietal performance of cabbage on the incidence of flea beetles (Phyllotreta spp.)

Κατά τη διάρκεια Σεπτεμβρίου 2007 - Φεβρουαρίου 2008 διεξήχθη πειραματισμός στο Γεωπονικό Πανεπιστήμιο Sher-e-Bangla (Μπαγκλαντές) για την αξιολόγηση της επίδρασης των φυλλοφάγων κολεοπτέρων εντόμων Phyllotreta spp. σε επτά ποικιλίες λαχάνου. Δοκιμάστηκαν οι ποικιλίες V1: BARI badhakopi-1/Provati, V2: BARI badhakopi-2/Agrodot, V3: Atlas-70, V4: Autumn queen, V5: Tropical queen, V6: T-776 και V7: Seisho YR. Η ποικιλία V5 αποδείχθηκε ως η λιγότρο ευπαθής όσον αφορά στην παρουσία σκαθαριών (μέσος όρος:  0,00 ακμαία/φυτό), στο ποσοστό προσβεβλημένων φύλλων (0.87 %) και στο ποσοστό των  προσβεβλημένων φυτών (2,00 %). Η εργασία αυτή προσφέρει στοιχεία χρήσιμα για την πιθανή αντιμετώπιση αυτών των εντόμων σε καλλιέργειες λαχάνου με την χρήση λιγότερο ευαίσθητων ποικιλιών. A study was conducted at the Sher-e-Bangla Agricultural University, Bangladesh, during September 2007 to February 2008 to evaluate the varietal performance of cabbage on the incidence of flea beetles [Phyllotreta spp., (Coleoptera: Chrysomelidae)]. The experiment was laid out in a Randomized Complete Block Design comprising seven varieties viz. V1: BARI badhakopi-1/Provati, V2: BARI badhakopi-2/Agrodot, V3: Atlas-70, V4: Autumn queen, V5: Tropical queen, V6: T-776 and V7: Seisho YR. Among the different varieties of cabbage V5 (Tropical queen) performed as the best variety in terms of the lowest incidence of flea beetles (0.00 larvae/plant), lowest percent of leaves infestation (0.87 %) as well as plant infestation (2 %) caused by flea beetles. These findings will be valuable for the most appropriate management of flea beetles