Exploring gravity wave characteristics in 3-D using a novel S-transform technique: AIRS/Aqua measurements over the Southern Andes and Drake Passage

Gravity waves (GWs) transport momentum and energy in the atmosphere, exerting a profound influence on the global circulation. Accurately measuring them is thus vital both for understanding the atmosphere and for developing the next generation of weather forecasting and climate prediction models. However, it has proven very difficult to measure the full set of GW parameters from satellite measurements, which are the only suitable observations with global coverage. This is particularly critical at latitudes close to 60° S, where climate models significantly under-represent wave momentum fluxes. Here, we present a novel fully 3-D method for detecting and characterising GWs in the stratosphere. This method is based around a 3-D Stockwell transform, and can be applied retrospectively to existing observed data. This is the first scientific use of this spectral analysis technique. We apply our method to high-resolution 3-D atmospheric temperature data from AIRS/Aqua over the altitude range 20–60 km. Our method allows us to determine a wide range of parameters for each wave detected. These include amplitude, propagation direction, horizontal/vertical wavelength, height/direction-resolved momentum fluxes (MFs), and phase and group velocity vectors. The latter three have not previously been measured from an individual satellite instrument. We demonstrate this method over the region around the Southern Andes and Antarctic Peninsula, the largest known sources of GW MFs near the 60° S belt. Our analyses reveal the presence of strongly intermittent highly directionally focused GWs with very high momentum fluxes (∼ 80–100 mPa or more at 30 km altitude). These waves are closely associated with the mountains rather than the open ocean of the Drake Passage. Measured fluxes are directed orthogonal to both mountain ranges, consistent with an orographic source mechanism, and are largest in winter. Further, our measurements of wave group velocity vectors show clear observational evidence that these waves are strongly focused into the polar night wind jet, and thus may contribute significantly to the "missing momentum" at these latitudes. These results demonstrate the capabilities of our new method, which provides a powerful tool for delivering the observations required for the next generation of weather and climate models

How well do stratospheric reanalyses reproduce high-resolution satellite temperature measurements?

Atmospheric reanalyses are data-assimilating weather models which are widely used as proxies for the true state of the atmosphere in the recent past. This is particularly the case for the stratosphere, where historical observations are sparse. But how realistic are these stratospheric reanalyses? Here, we resample stratospheric temperature data from six modern reanalyses (CFSR, ERA-5, ERA-Interim, JRA-55, JRA-55C and MERRA-2) to produce synthetic satellite observations, which we directly compare to retrieved satellite temperatures from COSMIC, HIRDLS and SABER and to brightness temperatures from AIRS for the 10-year period of 2003–2012. We explicitly sample standard public-release products in order to best assess their suitability for typical usage. We find that all-time all-latitude correlations between limb sounder observations and synthetic observations from full-input reanalyses are 0.97–0.99 at 30&thinsp;km in altitude, falling to 0.84–0.94 at 50&thinsp;km. The highest correlations are seen at high latitudes and the lowest in the sub-tropics, but root-mean-square (RMS) differences are highest (10&thinsp;K or greater) in high-latitude winter. At all latitudes, differences increase with increasing height. High-altitude differences become especially large during disrupted periods such as the post-sudden stratospheric warming recovery phase, in which zonal-mean differences can be as high as 18&thinsp;K among different datasets. We further show that, for the current generation of reanalysis products, a full-3-D sampling approach (i.e. one which takes full account of the instrument measuring volume) is always required to produce realistic synthetic AIRS observations, but is almost never required to produce realistic synthetic HIRDLS observations. For synthetic SABER and COSMIC observations full-3-D sampling is required in equatorial regions and regions of high gravity-wave activity but not otherwise. Finally, we use cluster analyses to show that full-input reanalyses (those which assimilate the full suite of observations, i.e. excluding JRA-55C) are more tightly correlated with each other than with observations, even observations which they assimilate. This may suggest that these reanalyses are over-tuned to match their comparators. If so, this could have significant implications for future reanalysis development.</p

An evaluation of a nurse led unit: an action research study

This study is an exemplar of working in a participatory way with members of the public and health and social care practitioners as co-researchers. A Nurse Consultant Older People working in a nurse-led bed, intermediate care facility in a community hospital acted as joint project lead with an academic researcher. From the outset, members of the public were part of a team of 16 individuals who agreed an evaluation focus and were involved in all stages of the research process from design through to dissemination. An extensive evaluation reflecting all these stakeholders’ preferences was undertaken. Methods included research and audit including: patient and carer satisfaction questionnaire surveys, individual interviews with patients, carers and staff, staff surveys, graffiti board, suggestion box, first impressions questionnaire, patient tracking and a bed census. A key aim of the study has been capacity building of the research team members which has also been evaluated. In terms of impact, the co-researchers have developed research skills and knowledge, grown in confidence, developed in ways that have impacted elsewhere in their lives, developed posters, presented at conferences and gained a better understanding of the NHS. The evaluation itself has provided useful information on the processes and outcomes of intermediate care on the ward which was used to further improve the service

Characteristics of young people accessing recently implemented Community Forensic Child and Adolescent Mental Health Services (F:CAMHS) in England: insights from national service activity data

Children and young people in contact with forensic child and adolescent mental health services present with more complex needs than young people in the general population. Recent policy in child and adolescent mental health has led to the implementation of new workstreams and programmes to improve service provision. This research examines the characteristics of children and young people referred to recently commissioned Community Forensic Child and Adolescent Services (F:CAMHS) and service activity during the frst 24 months of service. The study is a national cohort study to describe the population and investigate service provision and access across England. Secondary data on 1311 advice cases and 1406 referrals are included in analysis. Findings show that 71.9% of the sample had accessed mainstream CAMHS before their referral, 50.9% had experienced/witnessed multiple traumatic events and 58.4% of young people presented with multiple difculties. The results of the study highlight the complexity of the cohort and a need for interagency trauma-informed working. This is the frst study to describe the characteristics of children and young people referred to Community F:CAMHS and provides valuable information on pathways and needs to inform service policy and provision

A Formalization of the Theorem of Existence of First-Order Most General Unifiers

This work presents a formalization of the theorem of existence of most general unifiers in first-order signatures in the higher-order proof assistant PVS. The distinguishing feature of this formalization is that it remains close to the textbook proofs that are based on proving the correctness of the well-known Robinson's first-order unification algorithm. The formalization was applied inside a PVS development for term rewriting systems that provides a complete formalization of the Knuth-Bendix Critical Pair theorem, among other relevant theorems of the theory of rewriting. In addition, the formalization methodology has been proved of practical use in order to verify the correctness of unification algorithms in the style of the original Robinson's unification algorithm.Comment: In Proceedings LSFA 2011, arXiv:1203.542

Biomimetic Behaviours in Hydrogel Artificial Cells through Embedded Organelles

Artificial cells are biomimetic structures formed from molecular building blocks that replicate biological processes, behaviors, and architectures. Of these building blocks, hydrogels have emerged as ideal, yet underutilized candidates to provide a gel-like chassis in which to incorporate both biological and nonbiological componentry which enables the replication of cellular functionality. Here, we demonstrate a microfluidic strategy to assemble biocompatible cell-sized hydrogel-based artificial cells with a variety of different embedded functional subcompartments, which act as engineered synthetic organelles. The organelles enable the recreation of increasingly biomimetic behaviors, including stimulus-induced motility, content release through activation of membrane-associated proteins, and enzymatic communication with surrounding bioinspired compartments. In this way, we showcase a foundational strategy for the bottom–up construction of hydrogel-based artificial cell microsystems which replicate fundamental cellular behaviors, paving the way for the construction of next-generation biotechnological devices

An 18‐year climatology of directional stratospheric gravity wave momentum flux from 3‐D satellite observations

Atmospheric gravity waves (GWs) are key drivers of the atmospheric circulation, but their representation in general circulation models (GCMs) is challenging, leading to significant biases in middle atmospheric circulations. Unresolved GW momentum transport in GCMs must be parameterised, but global directional GW observations are needed to constrain this. Here we present an 18‐year climatology of directional stratospheric GW momentum flux (GWMF) from global AIRS/Aqua 3‐D satellite observations during 2002 to 2019. Striking hemispheric asymmetries are found at high latitudes, including dramatic reductions and reversals of GWMF during sudden stratospheric warmings. During southern hemisphere winter, a lateral convergence of GWMF towards 60°S is found that has no northern hemisphere counterpart. In the tropics, we find that zonal GWMF in AIRS measurements is strongly modulated by the semi‐annual oscillation (SAO) but not the quasi‐biennial oscillation (QBO). Our results provide guidance for future GW parameterisations needed to resolve long‐standing biases in GCMs

Radar observations of winds, waves and tides in the mesosphere and lower thermosphere over South Georgia island (54◦S, 36◦W) and comparison to WACCM simulations [in review]

The mesosphere and lower thermosphere (MLT) is a dynamic layer of the earth’s atmosphere. This region marks the interface at which neutral atmosphere dynamics begin to influence the ionosphere and space weather. However, our understanding of this region and our ability to accurately simulate it in global circulation models (GCMs) is limited by a lack of observations, especially in remote locations. To this end, a meteor radar was deployed on the remote mountainous island of South Georgia (54° S, 36° W) in the Southern Ocean from 2016 to 2020. The goal of this study is to use these new measurements to characterise the fundamental dynamics of the MLT above South Georgia including large-scale winds, solar tides, planetary waves (PWs) and mesoscale gravity waves (GWs). We first present an improved method for time-height localisation of radar wind measurements and characterise the large-scale MLT winds. We then explore the amplitudes and phases of the diurnal (24 h), semidiurnal (12 h) and terdiurnal (8 h) solar tides at this latitude. We also explore PW activity and find very large amplitudes up to 30 ms−1 for the quasi-2 day wave in summer and show that the dominant modes of the quasi-5, 10 and 16 day waves are westward W1 and W2. We investigate wind variance due to GWs in the MLT and use a new method to show an east-west tendency of GW variance of up to 20 % during summer and a weaker north-south tendency of 0–5 % during winter. This is contrary to the expected tendency of GW directions in the winter stratosphere below, which is a strong suggestion of secondary GW (2GW) observations in the MLT. Lastly, comparison of radar winds to a climatological Whole Atmosphere Community Climate Model (WACCM) simulation reveals a simulated summertime mesopause and zonal wind shear that occur at altitudes around 10 km lower than observed, and southward winds during winter above 90 km altitude in the model that are not seen in observations. Further, wintertime zonal winds above 85 km altitude are eastward in radar observations but in WACCM they are found to weaken and reverse to westward. Recent studies have linked this discrepancy to the impact of 2GWs on the residual circulation which are not included in WACCM. These measurements therefore provide vital constraints that can guide the development of GCMs as they extend upwards into this important region of the atmosphere

A novel long non-coding natural antisense RNA is a negative regulator of Nos1 gene expression

Long non-coding natural antisense transcripts (NATs) are widespread in eukaryotic species. Although recent studies indicate that long NATs are engaged in the regulation of gene expression, the precise functional roles of the vast majority of them are unknown. Here we report that a long NAT (Mm-antiNos1 RNA) complementary to mRNA encoding the neuronal isoform of nitric oxide synthase (Nos1) is expressed in the mouse brain and is transcribed from the non-template strand of the Nos1 locus. Nos1 produces nitric oxide (NO), a major signaling molecule in the CNS implicated in many important functions including neuronal differentiation and memory formation. We show that the newly discovered NAT negatively regulates Nos1 gene expression. Moreover, our quantitative studies of the temporal expression profiles of Mm-antiNos1 RNA in the mouse brain during embryonic development and postnatal life indicate that it may be involved in the regulation of NO-dependent neurogenesis