3,606 research outputs found
Lepton Flavor Violation at the LHC
Recent results from Super Kamiokande suggest mixing and
hence lepton flavor violation. In supersymmetric models, this flavor violation
may have implications for the pattern of slepton masses and mixings. Possible
signals for this mixing in the decays of sleptons produced at the LHC are
discussed. The sensitivity expected is compared to that of rare decays such as
.Comment: 14 pages, 9 figure
Epidemiology of tobacco smoking in patients undergoing elective vascular surgery in the UK
[no abstract
The effect of radiosensitizers on the pharmacokinetics of melphalan and cyclophosphamide in the mouse.
Misonidazole (MISO) has been shown to affect the pharmacokinetics of both cyclophosphamide (CY) and melphalan (MEL) in WHT mice resulting in increased plasma levels of the cytotoxic drugs. The effect is not solely due to the reduction in body temperature observed with large single doses of MISO, as a change in MEL pharmacokinetics was still observed when the mice were maintained at 37 degrees C. Inhibition of cytotoxic drug metabolism may also be a possible mechanism. Such a pharmacokinetic effect could account for part of the potentiation of MEL and CY action observed in tumours with large single doses of MISO. However, a chronic low dosing schedule of MISO did not affect the plasma half-life of either cytotoxic drug, although a significant potentiation of each drug in combination with a chronic MISO dose has been obtained in some tumours. These results suggest that potentiation of chemotherapeutic drug action by MISO in the clinical situation is unlikely to be due to changes in drug pharmacokinetics
Chemotactic Collapse and Mesenchymal Morphogenesis
We study the effect of chemotactic signaling among mesenchymal cells. We show
that the particular physiology of the mesenchymal cells allows one-dimensional
collapse in contrast to the case of bacteria, and that the mesenchymal
morphogenesis represents thus a more complex type of pattern formation than
those found in bacterial colonies. We finally compare our theoretical
predictions with recent in vitro experiments
Relaxation paths for single modes of vibrations in isolated molecules
A numerical simulation of vibrational excitation of molecules was devised,
and used to excite computational models of common molecules into a prescribed,
pure, normal vibration mode in the ground electronic state, with varying,
controlable energy content. The redistribution of this energy (either
non-chaotic or irreversible IVR) within the isolated, free molecule is then
followed in time with a view to determining the coupling strength between
modes. This work was triggered by the need to predict the general characters of
the infrared spectra to be expected from molecules in interstellar space, after
being excited by photon absorption or reaction with a radical. It is found that
IVR from a pure normal mode is very "restricted" indeed at energy contents of
one mode quantum or so. However, as this is increased, or when the excitation
is localized, our approach allows us to isolate, describe and quantify a number
of interesting phenomena, known to chemists and in non-linear mechanics, but
difficult to demonstrate experimentally: frequency dragging, mode locking or
quenching or, still, instability near a potential surface crossing, the first
step to generalized chaos as the energy content per mode is increased.Comment: 25 pages, 15 figures; accepted by J. Atom. Phys.
Navigating Choppy Waters: The QSEP Voyage from Multiple Perspectives
The Society’s Stage 2 Qualification in Sport and Exercise Psychology (QSEP) has been developed to provide an appropriate training route for those seeking to forge a career within our relatively fledgling domain. QSEP represents a positive advancement for the personal and professional development of aspiring practitioners, whilst also ensuring greater transparency for service users regarding the competence of Chartered Sport and Exercise Psychologists. Although QSEP has evolved into a rigorous and fairly standardised process of professional training, there remains a great deal of variation in the approaches to supervision and subsequent experiences of candidates. The aim of this symposium is to provide a descriptive and reflective account of a particular model of supervision being adopted at one host institution within the UK. In paper 1, Andrew Manley will provide an overview of this institutional model of supervision, setting the scene for the remainder of the symposium. Paper 2 will be delivered by Ross Shand, who will offer a reflective account of his QSEP experiences under this institutional model. In paper 3, Charlotte Hinchliffe will outline her role in the development and functioning of the Applied Sport Psychology Special Interest Group, as it looks to become an integral part of the institutional supervision model. Paper 4, delivered by Andrew Manley and Susan Backhouse, will provide a reflective summary of the QSEP process from perspectives of two Supervisors and Assessors. Finally, Jo Hudson will act as discussant, offering some conclusions and implications based on the presentations. The primary aim of this symposium is not to advocate a specific approach to QSEP supervision as an example of “best” practice, but rather an opportunity to share some insights regarding the benefits and challenges of operationalising a particular model of supervision from the perspectives of Trainees, Supervisors, and Assessors
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