ショウジョウバエのグルタミン作動性シナプスにおけるDisrupted-in-Schizophrenia 1とNeurexinの遺伝学的相互作用

筑波大学 (University of Tsukuba)201

ショウジョウバエのグルタミン作動性シナプスにおけるDisrupted-in-Schizophrenia 1とNeurexinの遺伝学的相互作用

筑波大学 (University of Tsukuba)201

Fuzzy Logic Based Hybrid Image Compression Technology

In this paper, the comparison between Hybrid Image Compressions methods and Fuzzy logic based image Compression is discussed. The Hybrid Comparison Method is a combination of both the DCT and DWT Image Compression method. When more than one compression technique are applied to compressed one image for high value of PSNR (peak signal to noise ratio) and CR (compression ratio) this process is called hybrid compression technique. For reducing MSE (mean square error) and for quality enhancement of an image Fuzzy Logic is applied to same image. The proposed work is designed using MATLAB. DOI: 10.17762/ijritcc2321-8169.150515

In vitro evaluation of Trichoderma species for virulence efficacy on Botryodiplodia palmarum

Trichoderma species are well known for their antagonistic activity against number of phytopathogens. They restrict the growth of pathogens by variety of means like parasitism, release of antibiotic volatile and non-volatile metabolites. The studies aimed to screen and evaluate the growth inhibition potential of six Trichoderma species against Botryodiplodia palmarum under laboratory conditions. The results revealed 37.56-61.95% growth inhibition of B. palmarum in dual culture, 12.59-43.46% and 4.38-78.08% respectively by the release of volatile and non-volatile metabolites. The growth inhibition was increased with period of incubation and concentration of culture filtrate of Trichoderma species in the culture media. Trichoderma harzianum was most effective among the selected species

Correlation coefficient and path analysis of yield and yield attributing characters of rice (Oryza sativa L.) genotypes under reproductive drought stress in the Terai region of Nepal

An experimental trial of nine rice genotypes was conducted in the Agronomy field of the Institute of Agriculture and Animal Science (IAAS) Paklihawa Campus under a randomized block design layout with three replications from July to November of 2022. The aim was to study genetic variability and analyze the character association of yield and yield-attributing components in rice genotypes and their direct and indirect effect on grain yield under reproductive drought stress conditions. Observations on days to flowering (50%), plant height, panicle length, panicle weight, number of grains/panicles, effective panicle/m², grain yield, and 1000 kernel weight were recorded. Grain yield showed a highly positive significant correlation with effective panicle/m² (0.713**), followed by plant height (0.347) and panicle length (0.289). The path coefficient analysis of different traits revealed the highest positive direct effect of the effective panicle per m² (0.748963), followed by panicle length (0.24145) and plant height (0.227505). The highest negative direct effect was shown by the number of grains per panicle (-0.31218). The experimental results revealed that the selection of trait-effective panicle per square meter would be most beneficial for the improvement of yield in rice genotypes facilitating selection and plant breeding programs

Genetic interaction of DISC1 and Neurexin in the development of fruit fly glutamatergic synapses

Originally identified at the breakpoint of a (1;11)(q42.1; q14.3) chromosomal translocation in a Scottish family with a wide range of mental disorders, the DISC1 gene has been a focus of intensive investigations as an entry point to study the molecular mechanisms of diverse mental dysfunctions. Perturbations of the DISC1 functions lead to behavioral changes in animal models, which are relevant to psychiatric conditions in patients. In this work, we have expressed the human DISC1 gene in the fruit fly (Drosophila melanogaster) and performed a genetic screening for the mutations of psychiatric risk genes that cause modifications of DISC1 synaptic phenotypes at the neuromuscular junction. We found that DISC1 interacts with dnrx1, the Drosophila homolog of the human Neurexin (NRXN1) gene, in the development of glutamatergic synapses. While overexpression of DISC1 suppressed the total bouton area on the target muscles and stimulated active zone density in wild-type background, a partial reduction of the dnrx1 activity negated the DISC1–mediated synaptic alterations. Likewise, overexpression of DISC1 stimulated the expression of a glutamate receptor component, DGLURIIA, in wild-type background but not in the dnrx1 heterozygous background. In addition, DISC1 caused mislocalization of Discs large, the Drosophila PSD-95 homolog, in the dnrx1 heterozygous background. Analyses with a series of domain deletions have revealed the importance of axonal localization of the DISC1 protein for efficient suppression of DNRX1 in synaptic boutons. These results thus suggest an intriguing converging mechanism controlled by the interaction of DISC1 and Neurexin in the developing glutamatergic synapses

A detailed study on trust management techniques for security and privacy in IoT: challenges, trends, and research directions

The Internet of Things is a modern technology that is directed at easing human life by automating most of the things used in daily life. The never-ending dependency on the network for communication is attracting adversaries to exploit the vulnerabilities of IoT. Therefore, this technology is facing some serious issues and challenges concerning security and privacy. These issues and challenges are the real motivation behind considering this study. Hence, this survey includes a discussion about security and privacy challenges as well as available solutions for IoT based wireless sensor networks. This systematic literature review (SLR) focuses particularly on a popular and applicable security approach known as Trust Management System (TMS). Firstly, all aspects of trust management, including trust indicators, trust properties, trust evaluation, trust building, trust models and the importance of those models for security and privacy, trust prediction methodologies, and ultimately trust-based attacks, are covered in this literature. Secondly, trust management schemes are classified into four groups based on the methodology used for trust-based security solutions in the IoT: cryptography-based, computational and probabilistic-based, information theory-based, and others. Then, an understanding of the problems and difficulties with current methodologies is given, along with suggestions for further research. Finally, the SLR is concluded by formulating the desirable characteristics of a trust management system in the IoT and proposing a trust model suitable for IoT networks

Extended spectrum beta lactamase producing Proteus penneri: A rare missed pathogen?

Indole negative Proteus species are invariably incorrectly identified as Proteus mirabilis, often missing out isolates of Proteus penneri. We report a case of extended spectrum beta lactamase producing and multidrug-resistant P. penneri isolated from pus from pressure sore of a patient of road traffic accident. Correct and rapid isolation and identification of such resistant pathogen are important as they are significant nosocomial threat