MeerKAT's View of the Bullet Cluster 1E 0657-55.8

The Bullet cluster (1E 0657-55.8) is a massive merging system at redshift $z$=0.296, known to host a powerful radio halo and a relic. Here we present high fidelity MeerKAT L-band (0.9-1.7 GHz) observations of the Bullet cluster, in which we trace a larger extent of both the radio halo and relic in comparison to previous studies. The size of the recovered radio halo is 1.6 Mpc $\times$ 1.3 Mpc and the largest linear size of the relic is ~988 kpc. We detect a new decrement feature on the southern outskirts of the halo emission, where a region appears to have a lower surface brightness in comparison to its surroundings. The fainter extension on the outskirts of the radio halo suggests a new wave of merger activity. An in-band spectral index map of the radio halo reveals a hint of radial steepening towards the edges of the diffuse source, likely due to synchrotron electron ageing. The integrated spectral index of the radio halo is 1.1$\pm$0.2. We perform a radio-X-ray surface brightness point-to-point analysis, which reveals a linear correlation for the radio halo. This indicates that the radio halo emission is produced by primary re-acceleration mechanisms. Finally, we derive a radio Mach number of M_R= 4.6$\pm$0.9 for the relic shock region, which is higher than the Mach number inferred by earlier analyses based on X-ray data. Discrepancies between radio and X-ray Mach numbers have been observed for multiple systems, with studies suggesting that this is due to various factors, including relic orientation.Comment: 11 pages, 6 figures. Submitted to MNRAS; corrected typo in the Mach numbe

Proximal genomic localization of STAT1 binding and regulated transcriptional activity

BACKGROUND: Signal transducer and activator of transcription (STAT) proteins are key regulators of gene expression in response to the interferon (IFN) family of anti-viral and anti-microbial cytokines. We have examined the genomic relationship between STAT1 binding and regulated transcription using multiple tiling microarray and chromatin immunoprecipitation microarray (ChIP-chip) experiments from public repositories. RESULTS: In response to IFN-γ, STAT1 bound proximally to regions of the genome that exhibit regulated transcriptional activity. This finding was consistent between different tiling microarray platforms, and between different measures of transcriptional activity, including differential binding of RNA polymerase II, and differential mRNA transcription. Re-analysis of tiling microarray data from a recent study of IFN-γ-induced STAT1 ChIP-chip and mRNA expression revealed that STAT1 binding is tightly associated with localized mRNA transcription in response to IFN-γ. Close relationships were also apparent between STAT1 binding, STAT2 binding, and mRNA transcription in response to IFN-α. Furthermore, we found that sites of STAT1 binding within the Encyclopedia of DNA Elements (ENCODE) region are precisely correlated with sites of either enhanced or diminished binding by the RNA polymerase II complex. CONCLUSION: Together, our results indicate that STAT1 binds proximally to regions of the genome that exhibit regulated transcriptional activity. This finding establishes a generalized basis for the positioning of STAT1 binding sites within the genome, and supports a role for STAT1 in the direct recruitment of the RNA polymerase II complex to the promoters of IFN-γ-responsive genes

35.4 T field generated using a layer-wound superconducting coil made of (RE)Ba2Cu3O7-x (RE = Rare Earth) coated conductor

To explore the limits of layer wound (RE)Ba2Cu3O7-x (REBCO, RE = Rare Earth) coils in a high magnetic field environment > 30 T, a series of small insert coils have been built and characterized in background fields. One of the coils repeatedly reached 35.4 T using a single ~100 m length of REBCO tape wet wound with epoxy and nested in a 31 T background magnet. The coil was quenched safely several times without degradation. Contributing to the success of this coil was the introduction of a thin polyester film that surrounded the conductor. This approach introduces a weak circumferential plane in the coil pack that prevents conductor delamination that has caused degradation of several epoxy impregnated coils previously made by this and other groups.Comment: 7 pages, 3 figures, 1 tabl

Comparison of Zn_{1-x}Mn_xTe/ZnTe multiple-quantum wells and quantum dots by below-bandgap photomodulated reflectivity

Large-area high density patterns of quantum dots with a diameter of 200 nm have been prepared from a series of four Zn_{0.93}Mn_{0.07}Te/ZnTe multiple quantum well structures of different well width (4 nm, 6 nm, 8 nm and 10 nm) by electron beam lithography followed by Ar+ ion beam etching. Below-bandgap photomodulated reflectivity spectra of the quantum dot samples and the parent heterostructures were then recorded at 10 K and the spectra were fitted to extract the linewidths and the energy positions of the excitonic transitions in each sample. The fitted results are compared to calculations of the transition energies in which the different strain states in the samples are taken into account. We show that the main effect of the nanofabrication process is a change in the strain state of the quantum dot samples compared to the parent heterostructures. The quantum dot pillars turn out to be freestanding, whereas the heterostructures are in a good approximation strained to the ZnTe lattice constant. The lateral size of the dots is such that extra confinement effects are not expected or observed.Comment: 23 pages, LaTeX2e (amsmath, epsfig), 7 EPS figure

Giant dipole resonance with exact treatment of thermal fluctuations

The shape fluctuations due to thermal effects in the giant dipole resonance (GDR) observables are calculated using the exact free energies evaluated at fixed spin and temperature. The results obtained are compared with Landau theory calculations done by parameterizing the free energy. The Landau theory is found to be insufficient when the shell effects are dominating.Comment: 5 pages, 2 figure

A 6 year study of mammographic compression force : practitioner variability within and between screening sites

Background The application of compression force in mammography is more heavily influenced by the practitioner rather than the client. This can affect client experience, radiation dose and image quality. This research investigates practitioner compression force variation over a 6 year screening cycle in three different screening units. Methods: Recorded data included: practitioner code, applied compression force(N), breast thickness(mm), BI-RADS® density category. Exclusion criteria included: previous breast surgery, previous/ongoing assessment, breast implants. 975 clients (2925) client visits, 11,700 mammogram images) met inclusion criteria across three sites. Data analysis assessed practitioner variation of compression force and breast thickness. Results: Practitioners across three breast screening sites behave differently in the application of compression force. Two of the three sites demonstrate variability within themselves, though they demonstrated no significant difference in mean, first and third quartile compression force and breast thickness values CC(p>0.5), MLO(p>0.1) between themselves. However, the third site (where mandate dictates a minimum compression force is applied) greater consistency was demonstrated; a significant difference in mean, first and third quartile compression force and breast thickness values(p<0.001) was demonstrated between this site and the other two sites. Conclusion: Stabilisation of variations in compression force may have a positive impact on image quality, radiation dose reduction, re-attendance levels and potentially cancer detection. The large variation in compression forces could negatively impact on client experience between the units and within a unit. Further research is required to establish best practice guidelines for compression force within mammography. Keywords: Compression force, Breast compression, Compression variabilit

Complete Genome Sequences of Paenibacillus Larvae Phages BN12, Dragolir, Kiel007, Leyra, Likha, Pagassa, PBL1c, and Tadhana

We present here the complete genomes of eight phages that infect Paenibacillus larvae, the causative agent of American foulbrood in honeybees. Phage PBL1c was originally isolated in 1984 from a P. larvae lysogen, while the remaining phages were isolated in 2014 from bee debris, honeycomb, and lysogens from three states in the USA

Comparison of Magnetic Field Structures on Different Scales in and around the Filamentary Dark Cloud GF 9

New visible polarization data combined with existing IR and FIR polarization data are used to study how the magnetic field threading the filamentary molecular cloud GF 9 connects to larger structures in its general environment. We find that when both visible and NIR polarization data are plotted as a function of extinction, there is no evidence for a plateau or a saturation effect in the polarization at Av ~ 1.3 as seen in dark clouds in Taurus. This lack of saturation effect suggests that even in the denser parts of GF 9 we are still probing the magnetic field. The visible polarization is smooth and has a well-defined orientation. The IR data are also well defined but with a different direction, and the FIR data in the core region are well defined and with yet another direction, but are randomly distributed in the filament region. On the scale of a few times the mean radial dimension of the molecular cloud, it is as if the magnetic field were `blind' to the spatial distribution of the filaments while on smaller scales within the cloud, in the core region near the IRAS point source PSC 20503+6006, polarimetry shows a rotation of the magnetic field lines in these denser phases. Hence, in spite of the fact that the spatial resolution is not the same in the visible/NIR and in the FIR data, all the data put together indicate that the field direction changes with the spatial scale. Finally, the Chandrasekhar and Fermi method is used to evaluate the magnetic field strength, indicating that the core region is approximately magnetically critical. A global interpretation of the results is that in the core region an original poloidal field could have been twisted by a rotating elongated (core+envelope) structure. There is no evidence for turbulence and ambipolar diffusion does not seem to be effective at the present time.Comment: 33 pages, 6 tables, 8 figures, Accepted by Ap