3,345 research outputs found
Financial convergence in the European Monetary Union?
EMS;convergence;financial markets
Sensory Evaluation and Consumers’ Willingness to Pay for Quality Protein Maize (QPM) using Experimental Auctions in Rural Tanzania
The purpose of this study was to evaluate the sensory characteristics and consumer acceptability of quality protein maize (QPM) in rural Tanzania. Due to the malnutrition problem facing consumers in developing countries, QPM which has almost double the amount of tryptophan and lysine, has been identified as a possible solution to this problem. To know whether consumers will accept QPM, it is vital that its sensory attributes and consumer acceptance tests are carried out. Sensory characteristics were determined using home use testing and central location methods by use of stiff porridge. Three districts were visited and 120 consumers participated in home use testing, whereas 30 respondents participated in the central location testing. At the central location, triangle test was also undertaken to find out if a difference exists between QPM and conventional maize. Additionally, acceptability of QPM was tested using BDM method. Consumer characteristics of QPM were highly appreciated for stiff porridge, a major maize product in East Africa. This was observed both in home use and sensory location testing. Likewise, consumers were willing to pay more for QPM than for conventional maize in all evaluation criteria used. Triangle test showed a significant difference between QPM and conventional maize. Sensory evaluation however needs to be repeated with other QPM varieties to ensure that it is not only a specific QPM variety that has favourable consumer characteristicsQPM, consumer acceptability, sensory evaluation, malnutrition, Tanzania, Crop Production/Industries, Demand and Price Analysis,
Preparing Mental Health Professionals for Work in Collaborative Care Settings
There has been a significant shift regarding how health and illness are conceptualized. In decades past, the biomedical model predominated. Factors other than biological were not seen as important with regard to the diagnosis and treatment of illness; mind and body were viewed as separate. Engel’s 1977 article challenged the biomedical perspective with the biopsychosocial model, suggesting the reciprocal nature of biological, psychological and social factors on patients’ experience of health and illness, and responsiveness to treatment interventions. While viewing individuals holistically was not a new concept at that time, several factors led the biopsychosocial model to gain wide acceptance among health care providers and institutions. The influence of the biopsychosocial model may be seen not only in the way patients’ providers conceptualize health concerns and develop treatment plans, but in the increasing collaboration among professionals from different disciplines in an effort to provide integrated care. Collaboration or a treatment team approach to health care delivery is now commonplace in hospitals and similar institutions. Degree of collaboration and the extent to which responsibilities overlap among different disciplines varies; there are several models of collaboration: multidisciplinary, interdisciplinary and transdisciplinary. Early career psychologists and trainees (doctoral students completing practicum and internship placements) are presented with the challenges of understanding collaborative care and effectively integrating themselves into treatment teams. Research indicates that there are limited opportunities for health care professionals (of various disciplines) to gain adequate understanding of collaborative care from coursework or practical experiences prior to completing their studies. This project proposes a two-pronged approach to preparing mental health professionals to work in collaborative care. The first component recommends acquisition of knowledge regarding the team approach, including an understanding the historical context of the biopsychosocial model and collaborative health care, and development of an understanding of the educational requirements, roles and responsibilities of professionals often represented on treatment teams. The second component is the effective integration of early career professionals and trainees into teams, which requires the active engagement of trainees, their supervisors and training sites
Deep Reinforcement Learning for Join Order Enumeration
Join order selection plays a significant role in query performance. However,
modern query optimizers typically employ static join enumeration algorithms
that do not receive any feedback about the quality of the resulting plan.
Hence, optimizers often repeatedly choose the same bad plan, as they do not
have a mechanism for "learning from their mistakes". In this paper, we argue
that existing deep reinforcement learning techniques can be applied to address
this challenge. These techniques, powered by artificial neural networks, can
automatically improve decision making by incorporating feedback from their
successes and failures. Towards this goal, we present ReJOIN, a
proof-of-concept join enumerator, and present preliminary results indicating
that ReJOIN can match or outperform the PostgreSQL optimizer in terms of plan
quality and join enumeration efficiency
The relationship between tumour budding, the tumour microenvironment and survival in patients with primary operable colorectal cancer
Background:
Tumour budding has been reported to reflect invasiveness, metastasis and unfavourable prognosis in colorectal cancer. The aim of the study was to examine the relationship between tumour budding and clinicopathological characteristics, tumour microenvironment and survival in patients with primary operable colorectal cancer.
Methods:
A total of 303 patients from a prospective data set of patients with primary operable colorectal cancer were included in the study. The presence of budding was determined through assessment of all tumour-containing H&E slides and the number of tumour buds was counted using a 10 high-powered field method. Routine pathologic sections were used to assess: tumour necrosis, the tumour inflammatory cell infiltrate using Klintrup–Makinen (KM) grade and tumour stroma percentage (TSP) combined as the Glasgow Microenvironment Score (GMS).
Results:
High-grade tumour budding was present in 39% of all tumours and in 28% of node-negative tumours respectively. High-grade budding was significantly associated with T stage (P<0.001), N stage (P<0.001), TNM stage (P<0.001), serosal involvement (P<0.001), venous invasion (P<0.005), KM grade (P=0.022), high tumour stroma (P<0.001) and GMS (P<0.001). Tumour budding was associated with reduced cancer-specific survival (CSS) (HR=4.03; 95% confidence interval (CI), 2.50–6.52; P<0.001), independent of age (HR=1.47; 95% CI, 1.13–1.90; P=0.004), TNM stage (HR=1.52; 95% CI, 1.02–2.25; P=0.040), venous invasion (HR=1.73; 95% CI, 1.13–2.64; P=0.012) and GMS (HR=1.54; 95% CI, 1.15–2.07; P=0.004).
Conclusions:
The presence of tumour budding was associated with elements of the tumour microenvironment and was an independent adverse prognostic factor in patients with primary operable colorectal cancer. Specifically high tumour budding stratifies effectively the prognostic value of tumour stage, venous invasion and GMS. Taken together, tumour budding should be assessed routinely in patients with primary operable colorectal cancer
Interaction of Supernova Ejecta with Nearby Protoplanetary Disks
The early Solar System contained short-lived radionuclides such as 60Fe (t1/2
= 1.5 Myr) whose most likely source was a nearby supernova. Previous models of
Solar System formation considered a supernova shock that triggered the collapse
of the Sun's nascent molecular cloud. We advocate an alternative hypothesis,
that the Solar System's protoplanetary disk had already formed when a very
close (< 1 pc) supernova injected radioactive material directly into the disk.
We conduct the first numerical simulations designed to answer two questions
related to this hypothesis: will the disk be destroyed by such a close
supernova; and will any of the ejecta be mixed into the disk? Our simulations
demonstrate that the disk does not absorb enough momentum from the shock to
escape the protostar to which it is bound. Only low amounts (< 1%) of mass loss
occur, due to stripping by Kelvin-Helmholtz instabilities across the top of the
disk, which also mix into the disk about 1% of the intercepted ejecta. These
low efficiencies of destruction and injectation are due to the fact that the
high disk pressures prevent the ejecta from penetrating far into the disk
before stalling. Injection of gas-phase ejecta is too inefficient to be
consistent with the abundances of radionuclides inferred from meteorites. On
the other hand, the radionuclides found in meteorites would have condensed into
dust grains in the supernova ejecta, and we argue that such grains will be
injected directly into the disk with nearly 100% efficiency. The meteoritic
abundances of the short-lived radionuclides such as 60Fe therefore are
consistent with injection of grains condensed from the ejecta of a nearby (< 1
pc) supernova, into an already-formed protoplanetary disk.Comment: 57 pages, 16 figure
The 1997 event in the Crab pulsar revisited
A complex event observed in the radio pulses from the Crab pulsar in 1997
included echoes, a dispersive delay, and large changes in intensity. It is
shown that these phenomena were due to refraction at the edge of a plasma cloud
in the outer region of the Crab Nebula. Several similar events have been
observed, although in less detail. It is suggested that the plasma cloud is in
the form of filaments with diameter around 3 x 10^11m and electron density of
order 10^4 cm-3Comment: 5 pages 4 figs Accepted by MNRA
A VLA Search for Water Masers in Six HII Regions: Tracers of Triggered Low-Mass Star Formation
We present a search for water maser emission at 22 GHz associated with young
low-mass protostars in six HII regions -- M16, M20, NGC 2264, NGC 6357, S125,
and S140. The survey was conducted with the NRAO Very Large Array from 2000 to
2002. For several of these HII regions, ours are the first high-resolution
observations of water masers. We detected 16 water masers: eight in M16, four
in M20, three in S140, and one in NGC 2264. All but one of these were
previously undetected. No maser emission was detected from NGC 6357 or S125.
There are two principle results to our study. (1) The distribution of water
masers in M16 and M20 does not appear to be random but instead is concentrated
in a layer of compressed gas within a few tenths of a parsec of the ionization
front. (2) Significantly fewer masers are seen in the observed fields than
expected based on other indications of ongoing star formation, indicating that
the maser-exciting lifetime of protostars is much shorter in HII regions than
in regions of isolated star formation. Both of these results confirm
predictions of a scenario in which star formation is first triggered by shocks
driven in advance of ionization fronts, and then truncated approximately 10^5
years later when the region is overrun by the ionization front.Comment: 30 pages, 20 figures, 3 tables. Accepted for publication by ApJ. Full
resolution figures and PS and PDF versions with full-res figures available at
http://eagle.la.asu.edu/healy/preprints/hhc0
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