Quantum computation on a 19-qubit wide 2d nearest neighbour qubit array

In this paper, we explore the relationship between the width of a qubit lattice constrained in one dimension and physical thresholds for scalable, fault-tolerant quantum computation. To circumvent the traditionally low thresholds of small fixed-width arrays, we deliberately engineer an error bias at the lowest level of encoding using the surface code. We then address this engineered bias at a higher level of encoding using a lattice-surgery surface code bus that exploits this bias, or a repetition code to make logical qubits with unbiased errors out of biased surface code qubits. Arbitrarily low error rates can then be reached by further concatenating with other codes, such as Steane [[7,1,3]] code and the [[15,7,3]] CSS code. This enables a scalable fixed-width quantum computing architecture on a square qubit lattice that is only 19 qubits wide, given physical qubits with an error rate of $8.0\times 10^{-4}$. This potentially eases engineering issues in systems with fine qubit pitches, such as quantum dots in silicon or gallium arsenide.Comment: 34 pages, 19 figure

Continuous near-bottom gravity measurements made with a BGM-3 gravimeter in DSV Alvin on the East Pacific Rise crest near 9°31 'N and 9°50'N

A Bell BGM-3 gravimeter has been used to collect continuous, underway, near-bottom (3- to 10-m altitude) gravity measurements from the deep-diving submersible DSV Alvin during surveys on the East Pacific Rise (EPR) crest near 9° 31'N and 9° 50'N. Closely spaced (20- to 30-m) gravity measurements were made along transects up to 8 km-long in both regions. Repeatability of measurements made at the same location on different dives is ~ 0.3 mGal. Along-track spatial resolution of anomalies is ~130-160 m, with the limiting factors being precision and sampling rate of the pressure gauge depth data used to calculate vertical accelerations of the submersible. The average upper crustal density of the ridge crest determined from the relationship between depth and free-water gravity anomalies varies greatly between 9 °31 'N and 9° 50'N. Average upper crustal densities of2410 kg/m3 for the 9° 50'N area and 2690 kg/m3 for the 9° 31'N area were calculated. The different densities are not due to differing geometry of the Layer 2A-2B boundary or a regional cross-axis gravity gradient. Differences in porosity of the shallow crustal rocks, or a difference in the proportion of low-density extrusives to higher-density dikes and sills within Layer 2A in these two areas, are the likely causes of the different upper crustal densities. Bouguer gravity anomalies near the EPR axis are primarily small amplitude (0.5-2 mGal), are a few hundred meters across, and appear to be lineated parallel to the axis. Larger-amplitude Bouguer anomalies of up to 4 mGal were found at a few locations across the crestal plateau and are associated with pillow ridges composed of lavas which are clearly younger than the surrounding seafloor. These ridges have distinct chemical compositions compared to lavas from the axial summit collapse trough (ASCT) at the same latitude. Probable sources of the 0.5- to 2-mGal anomalies observed on the summit plateau include areas of collapsed and fissured terrain and dike swarms feeding melt through Layer 2A to the surface. A grid survey of the ridge axis near 9° 50'N shows Bouguer anomalies lineated along the axis, suggesting that dike swarms do contribute to the observed Bouguer anomalies. The along-axis continuity of the gravity anomalies is disrupted at a 75-m offset of the ASCT, suggesting that shallow feeders of lava to the surface may be segmented on a finer scale than the deeper crustal magmatic system. This initial study confirms the ability to conduct high-resolution, near-bottom, continuous gravity measurements from Alvin. It also provides important information on how the shallow crustal structure of a fast spreading mid-ocean ridge develops and how it varies with the surface morphology

Coherent terabit communications with microresonator Kerr frequency combs

Optical frequency combs enable coherent data transmission on hundreds of wavelength channels and have the potential to revolutionize terabit communications. Generation of Kerr combs in nonlinear integrated microcavities represents a particularly promising option enabling line spacings of tens of GHz, compliant with wavelength-division multiplexing (WDM) grids. However, Kerr combs may exhibit strong phase noise and multiplet spectral lines, and this has made high-speed data transmission impossible up to now. Recent work has shown that systematic adjustment of pump conditions enables low phase-noise Kerr combs with singlet spectral lines. Here we demonstrate that Kerr combs are suited for coherent data transmission with advanced modulation formats that pose stringent requirements on the spectral purity of the optical source. In a first experiment, we encode a data stream of 392 Gbit/s on subsequent lines of a Kerr comb using quadrature phase shift keying (QPSK) and 16-state quadrature amplitude modulation (16QAM). A second experiment shows feedback-stabilization of a Kerr comb and transmission of a 1.44 Tbit/s data stream over a distance of up to 300 km. The results demonstrate that Kerr combs can meet the highly demanding requirements of multi-terabit/s coherent communications and thus offer a solution towards chip-scale terabit/s transceivers

Core competencies for pain management: results of an interprofessional consensus summit.

ObjectiveThe objective of this project was to develop core competencies in pain assessment and management for prelicensure health professional education. Such core pain competencies common to all prelicensure health professionals have not been previously reported.MethodsAn interprofessional executive committee led a consensus-building process to develop the core competencies. An in-depth literature review was conducted followed by engagement of an interprofessional Competency Advisory Committee to critique competencies through an iterative process. A 2-day summit was held so that consensus could be reached.ResultsThe consensus-derived competencies were categorized within four domains: multidimensional nature of pain, pain assessment and measurement, management of pain, and context of pain management. These domains address the fundamental concepts and complexity of pain; how pain is observed and assessed; collaborative approaches to treatment options; and application of competencies across the life span in the context of various settings, populations, and care team models. A set of values and guiding principles are embedded within each domain.ConclusionsThese competencies can serve as a foundation for developing, defining, and revising curricula and as a resource for the creation of learning activities across health professions designed to advance care that effectively responds to pain

The Bose-Einstein Condensate and Cold Atom Laboratory

© 2020, The Author(s). Microgravity eases several constraints limiting experiments with ultracold and condensed atoms on ground. It enables extended times of flight without suspension and eliminates the gravitational sag for trapped atoms. These advantages motivated numerous initiatives to adapt and operate experimental setups on microgravity platforms. We describe the design of the payload, motivations for design choices, and capabilities of the Bose-Einstein Condensate and Cold Atom Laboratory (BECCAL), a NASA-DLR collaboration. BECCAL builds on the heritage of previous devices operated in microgravity, features rubidium and potassium, multiple options for magnetic and optical trapping, different methods for coherent manipulation, and will offer new perspectives for experiments on quantum optics, atom optics, and atom interferometry in the unique microgravity environment on board the International Space Station

MRI follow-up of conservatively treated meniscal knee lesions in general practice

Objective: To evaluate meniscal status change on follow-up MRI after 1 year, prognostic factors and association with clinical outcome in patients with conservatively treated knee injury. Methods: We analysed 403 meniscal horns in 101 conservatively treated patients (59 male; mean age 40 years) in general practice who underwent initial knee MRI within 5 weeks of trauma. We performed ordinal logistic regression analysis to analyse prognostic factors for meniscal change on follow-up MRI after 1 year, and we assessed the association with clinical outcome. Results: On follow-up MRI 49 meniscal horns had deteriorated and 18 had improved. Age (odds ratio [OR] 1.3/decade), body weight (OR 1.2/10 kg), total anterior cruciate ligament (ACL) rupture on initial MRI (OR 2.4), location in the posterior horn of the medial meniscus (OR 3.0) and an initial meniscal lesion (OR 0.3) were statistically significant predictors of meniscal MRI appearance change after 1 year, which was not associated with clinical outcome. Conclusion: In conservatively treated patients, meniscal deterioration on follow-up MRI 1 year after trauma is predicted by higher age and body weight, initial total ACL rupture, and location in the medial posterior horn. Change in MRI appearance is not associated with clinical outcome

The stranding anomaly as population indicator: the case of Harbour Porpoise <i>Phocoena phocoena</i> in North-Western Europe

Ecological indicators for monitoring strategies are expected to combine three major characteristics: ecological significance, statistical credibility, and cost-effectiveness. Strategies based on stranding networks rank highly in cost-effectiveness, but their ecological significance and statistical credibility are disputed. Our present goal is to improve the value of stranding data as population indicator as part of monitoring strategies by constructing the spatial and temporal null hypothesis for strandings. The null hypothesis is defined as: small cetacean distribution and mortality are uniform in space and constant in time. We used a drift model to map stranding probabilities and predict stranding patterns of cetacean carcasses under H-0 across the North Sea, the Channel and the Bay of Biscay, for the period 1990-2009. As the most common cetacean occurring in this area, we chose the harbour porpoise <i>Phocoena phocoena</i> for our modelling. The difference between these strandings expected under H-0 and observed strandings is defined as the stranding anomaly. It constituted the stranding data series corrected for drift conditions. Seasonal decomposition of stranding anomaly suggested that drift conditions did not explain observed seasonal variations of porpoise strandings. Long-term stranding anomalies increased first in the southern North Sea, the Channel and Bay of Biscay coasts, and finally the eastern North Sea. The hypothesis of changes in porpoise distribution was consistent with local visual surveys, mostly SCANS surveys (1994 and 2005). This new indicator could be applied to cetacean populations across the world and more widely to marine megafauna

Knee disorders in primary care: design and patient selection of the HONEUR knee cohort.

BACKGROUND: Knee complaints are a frequent reason for consultation in general practice. These patients constitute a specific population compared to secondary care patients. However, information to base treatment decisions on is generally derived from specialistic settings. Our cohort study is aimed at collecting knowledge about prognosis and prognostic factors of knee complaints presented in a primary care setting. This paper describes the methods used for data collection, and discusses potential selectiveness of patient recruitment. METHODS: This is a descriptive prospective cohort study with one-year follow-up. 40 Dutch GPs recruited consecutive patients with incident knee complaints aged 12 years and above from October 2001 to October 2003. Patients were assessed with questionnaires and standardised physical examinations. Additional measurements of subgroups included MRI for recent knee traumas and device assessed function measurements for non-traumatic patients. After the inclusion period we retrospectively searched the computerized medical files of participating GPs to obtain a sample to determine possible selective recruitment. We assessed differences in proportions of gender, traumatic onset of injury and age groups between participants and non-participants using Odds Ratios (OR) and 95% confidence intervals. RESULTS: We recruited 1068 patients. In a sample of 310 patients visiting the GP, we detected some selective recruitment, indicating an underrepresentation of patients aged 12 to 35 years (OR 1.70; 1.15-2.77), especially among men (OR 2.16; 1.12-4.18). The underrepresentation of patients with traumatic onset of injury was not statistically significant. CONCLUSION: This cohort is unique in its size, setting, and its range of both age and type of knee complaints. We believe the detected selective recruitment is unlikely to introduce significant bias, as the cohort will be divided into subgroups according to age group or traumatic onset of injury for future analyses. However, the underrepresentation of men in the age group of 12 to 35 years of age warrants caution. Based on the available data, we believe our cohort is an acceptable representation of patients with new knee complaints consulting the GP, and we expect no problems with extrapolation of the results to the general Dutch population