476 research outputs found

    Early Childhood Father Absence and Depressive Symptoms in Adolescent Girls from a UK Cohort:The Mediating Role of Early Menarche

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    # The Author(s) 2014. This article is published with open access at Springerlink.com Abstract Absence of the biological father in early childhood has been linked to depressive symptoms in mid-adolescent girls. Earlier studies have linked father absence to early timing of menarche, and early menarche is a risk factor for increased depressive symptoms in adolescence. No studies, however, have examined whether the association between father ab-sence and depressive symptomsmay be explained by the early onset of menarche. This study investigated whether age at menarche mediates the association between father absence in early childhood (birth to 5 years) and depressive symptoms in adolescent girls aged 14 years. The study sample comprised 7056 girls from a large UK birth cohort (Avon Longitudinal Study of Parents and Children) who provided data on age at onset of menarche and depressive symptoms assessed using the Short Mood and Feelings Questionnaire at 14 years. Mothers provided data on father absence from the birth of the study child up to 10 years. Using structural equation modelling, we found that 15 % of the total estimated associ-ation between father absence in early childhood and depres-sive symptoms at 14 years was explained by early age at menarche. In addition to the mediated effect, father absence was linked to an 11 % increase in depressive symptoms in adolescence. The findings suggest that early age at menarche is one of the pathways linking early childhood father absence and depressive symptoms in mid-adolescent girls. Preventive strategies could be targeting young girls at risk for depressive symptoms as a function of stressful family factors (e.g., bio-logical father absence) and earlier menarche

    Challenging the view that lack of fibre causes childhood constipation

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    Objectives: To assess evidence supporting the view that ‘low fibre causes childhood constipation’. Design: Triangulation integrated three approaches: a systematic review NICE guideline CG99 examining effectiveness of increasing fibre; a cohort study, Avon Longitudinal Study of Parents and Children (ALSPAC), to assess if constipation (or hard stools) can precede fibre intake at weaning; and a literature search for twin studies to calculate heredity. Setting: CG99 examined the literature regarding the effectiveness of increasing fibre. ALSPAC asked parents about: hard stools at 4 weeks, 6 months and 2.5 years and constipation at age 4–10 years, as well as fibre intake at 2 years. Twin studies and data from ALSPAC were pooled to calculate concordance of constipation comparing monozygotic and dizygous twin pairs. Participants: CG99 reported six randomised controlled trials (RCTs). ALSPAC hard stool data from 6796 children at 4 weeks, 9828 at 6 months and 9452 at 2.5 years plus constipation data on 8401 at 4–10 years were compared with fibre intake at 2 years. Twin studies had 338 and 93 twin pairs and ALSPAC added a further 45. Results: Increasing fibre did not effectively treat constipation. Hard stools at 4 weeks predated fibre and at 6 months predicted lower fibre intake at 2 years (p=0.003). Heredity explained 59% of constipation. Conclusions: RCTs indicate that increasing fibre is not an effective treatment for constipation in children. Hard stools can precede and predict later fibre intake. Genetic inheritance explains most childhood constipation. Extended treatment with stool softeners may improve fibre intake and limit long-term damaging sequelae of constipation

    Stressful events in early childhood and developmental trajectories of bedwetting at school age

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    Objective To examine whether early stressful events are associated with developmental trajectories of bedwetting. Methods This is a prospective cohort study comprising 8,761 participants from the Avon Longitudinal Study of Parents and Children. Stressful events were measured using a maternal questionnaire completed at 3 time points before their child was 4 years old. The association between stressful events and trajectories of bedwetting from 4 to 9 years was examined using multinomial regression. Results The association with stressful events was strongest for the frequent persistent bedwetting trajectory (wetting at least twice a week up to age 9). A 1 standard deviation increase in the stressful events score was associated with a 29% (13–47%) increase in the odds of experiencing frequent persistent bedwetting compared with normal attainment of nighttime bladder control. Conclusions Clinicians and parents should be aware that continence is a developmental outcome that is associated with high levels of stress in the family
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