A framework of industrial sustainability good practices

Global environmental problems, energy and raw material prices as well as their availability, increasingly demanding legislation and environmental taxes are some of the reasons that drive the consideration of sustainability concepts and practices into company operations. This paper presents the research carried out in order to capture industrial sustainability good practices and represent them into a framework to help companies increase their awareness and adopt practices to embed them within their operational processes

All-cause mortality in the cohorts of the Spanish AIDS Research Network (RIS) compared with the general population: 1997Ł2010

Abstract Background: Combination antiretroviral therapy (cART) has produced significant changes in mortality of HIVinfected persons. Our objective was to estimate mortality rates, standardized mortality ratios and excess mortality rates of cohorts of the AIDS Research Network (RIS) (CoRIS-MD and CoRIS) compared to the general population. Methods: We analysed data of CoRIS-MD and CoRIS cohorts from 1997 to 2010. We calculated: (i) all-cause mortality rates, (ii) standardized mortality ratio (SMR) and (iii) excess mortality rates for both cohort for 100 personyears (py) of follow-up, comparing all-cause mortality with that of the general population of similar age and gender. Results: Between 1997 and 2010, 8,214 HIV positive subjects were included, 2,453 (29.9%) in CoRIS-MD and 5,761 (70.1%) in CoRIS and 294 deaths were registered. All-cause mortality rate was 1.02 (95% CI 0.91-1.15) per 100 py, SMR was 6.8 (95% CI 5.9-7.9) and excess mortality rate was 0.8 (95% CI 0.7-0.9) per 100 py. Mortality was higher in patients with AIDS, hepatitis C virus (HCV) co-infection, and those from CoRIS-MD cohort (1997. Conclusion: Mortality among HIV-positive persons remains higher than that of the general population of similar age and sex, with significant differences depending on the history of AIDS or HCV coinfection

Sustainability best practices in operations

Consulta en la Biblioteca ETSI Industriales (7933)[EN] The aim of this project is to investigate sustainability best practices to be embedded in the sponsoring company¿s operational processes, in order to backup its commitments in supporting the global environment while maintaining its competitive advantage. The development of the project was divided into two main stages: (1) Develop a sustainability best practice framework/library by means of industrial field studies; (2) Analyse the sponsoring company¿s sustainability framework and operational processes, identifying areas for improvement.Hernando Anta, P. (2008). Sustainability best practices in operations. http://hdl.handle.net/10251/34391

Osteoarticular cryptococcosis successfully treated with high-dose liposomal amphotericin B followed by oral fluconazole

Background: Skeletal involvement of Cryptococcus neoformans is infrequent and usually associated with disseminated cryptococcosis or underlying predisposing conditions. We present an atypical case of osteoarticular cryptococcosis in an immunocompetent patient. Case presentation: We herein report a case of bone and soft tissue cryptococcal infection in a 42-year-old male from Pakistan with well-controlled diabetes without other associated immunodeficiencies treated with antifungal therapy without surgical debridement. Furthermore, the patient developed toxidermia due to fluconazole use, so a fluconazole desensitization was performed. Therapeutic management also included the performance of therapeutic drug monitoring of fluconazole plasma concentrations. Conclusion: To our knowledge, this is the first case of osteoarticular cryptococcosis treated with this treatment regimen. This strategy may be of interest to try to reduce hospital stay and associated complications