Análisis estructural de sectores estratégicos : sector de la confección Período 2007-2011

Durante los últimos años, la facultad de Administración de Empresas de la Universidad del Rosario ha venido desarrollando análisis de diversos sectores de la economía nacional con el fin de conformar una base de datos que permita avanzar en la identificación de factores que contribuyen al logro de la perdurabilidad. El presente documento contiene el estudio del sector textil, uno de los mayores generadores de empleo en el país. La metodología implementada es el análisis estructural de sectores estratégicos AESE, que incluye la prueba del hacinamiento, el levantamiento del panorama competitivo, el análisis de las fuerzas de mercado y el estudio de competidores. El estudio fue realizado por estudiantes de la asignatura Estrategia de Empresa I orientados por el profesor Hugo Alberto Rivera, director de la línea de investigación en perdurabilidad empresarial de la facultad de Administración

Impacto de la Atención al Cliente y el Desempeño del Personal en el Sistema de Gestión de la Calidad en la Coordinación de Administración Escolar de la UAZ

La calidad concebida como la capacidad de un servicio para ser de manera satisfactoria los deberes y superar las expectativas del cliente, es por esta razón que surge la necesidad de implementar un modelo de administración basado en un sistema de gestión de calidad apoyado en los estándares internacionales de la norma ISO 9001 aplicado en la Coordinación de Administración Escolar de la UAZ. Como aspectos fundamentales de la calidad de los servicios, para el modelo de administración, se tiene en primera instancia la puntualidad, que se debe realizar en el periodo prometido, el segundo pero menos importante es la cortesía, que se debe realizar alegremente, la constancia que es proporcionar a todos los clientes experiencias similares en todas las ocasiones, la cuarta es la convivencia,  que es la facilidad de acceso para los clientes, la quinta es el servicio completo, que se termina según lo requerido, y por último la exactitud que se refiere a realizado correctamente en cada ocasión. Una desventaja en cuanto a la implementación de modelos de administración basados en los sistemas de gestión de calidad es costosa, ya que las organizaciones que no pueden ofrecer servicios de calidad no tendrán la capacidad para competir con éxito. Con base en lo expuesto en lo anterior se realizó el estudio en base a una metodología cuantitativa, con una muestra de 377 usuarios de servicio para conocer y estudiar a fondo, la atención al cliente y el desempeño del personal y el impacto que tiene con el sistema de gestión de la calidad en la coordinación de la administración escolar de la Universidad Autónoma de Zacatecas.Quality conceived as the ability of a service to satisfactorily fulfill its duties and exceed customer expectations. For this reason, the need arises to implement an administration model based on a quality management system supported by international standards. of the ISO 9001 standard applied in the School Administration Coordination of the UAZ. As fundamental aspects of the quality of the services, for the administration model, there is, in the first instance, punctuality, which must be carried out within the promised period, the second but less important is courtesy, which must be carried out cheerfully, consistency which is to provide all customers with similar experiences on all occasions, the fourth is conviviality, which is the ease of access for customers, the fifth is the complete service, which is completed as required, and finally the accuracy that refers to performed correctly on each occasion. A disadvantage of implementing management models based on quality management systems is that it is costly, as organizations that cannot offer quality services will not have the ability to compete successfully. Based on the above, the study was carried out based on a quantitative methodology, with a sample of 377 service users to know and study in depth, customer service and staff performance and the impact it has on the quality management system in the coordination of the school administration of the Autonomous University of Zacatecas

Remoción del colorante AV7 presente en solución acuosa mediante carbón activado

Se investigó la remoción del colorante ácido violeta 7 mediante carbón activado en un sistema de adsorción en lote. Se estudiaron los efectos de parámetros experimentales en la capacidad de adsorción, tales como la masa del adsorbente y el pH. Las mejores condiciones experimentales para la adsorción de ácido violeta 7 fueron a pH natural del colorante (pH 6) y 100 mg de adsorbente al obtener una capacidad de adsorción de 102 mg/g. La cinética de adsorción fue descrita por el modelo de Pseudo-Segundo orden que está basado en un mecanismo de quimisorción

Alternative Eco-Friendly Methods in the Control of Post-Harvest Decay of Tropical and Subtropical Fruits

The effectiveness on several fruits by the application of alternative methods against fungi is summarized in the present chapter. Several investigations have reported the efficacy of these technologies for controlling fungal infections. Currently, high post-harvest loses have been reported due to several factors such as inefficient management, lack of training for farmers, and problems with appropriate conditions for storage of fruits and vegetables. Even now, in many countries, post-harvest disease control is led by the application of chemical fungicides. However, in this time, awareness about fungi resistance, environmental, and health issues has led to the research of eco-friendly and effective alternatives for disease management. The pathogen establishment on fruits can be affected by the application of GRAS compounds like chitosan, essential oils, salts, among others; besides, their efficacy can be enhanced by their combination with other technologies like ultrasound. Thus, the applications of these alternatives are suitable approaches for post-harvest management of fruits

Evaluation of the humoral and mucosal immune response of a multiepitope vaccine against COVID-19 in pigs

IntroductionThis study evaluated the immune response to a multiepitope recombinant chimeric protein (CHIVAX) containing B- and T-cell epitopes of the SARS-CoV-2 spike’s receptor binding domain (RBD) in a translational porcine model for pre-clinical studies.MethodsWe generated a multiepitope recombinant protein engineered to include six coding conserved epitopes from the RBD domain of the SARS-CoV-2 S protein. Pigs were divided into groups and immunized with different doses of the protein, with serum samples collected over time to determine antibody responses by indirect ELISA and antibody titration. Peptide recognition was also analyzed by Western blotting. A surrogate neutralization assay with recombinant ACE2 and RBDs was performed. Intranasal doses of the immunogen were also prepared and tested on Vietnamese minipigs.ResultsWhen the immunogen was administered subcutaneously, it induced specific IgG antibodies in pigs, and higher doses correlated with higher antibody levels. Antibodies from immunized pigs recognized individual peptides in the multiepitope vaccine and inhibited RBD-ACE2 binding for five variants of concern (VOC). Comparative antigen delivery methods showed that both, subcutaneous and combined subcutaneous/intranasal approaches, induced specific IgG and IgA antibodies, with the subcutaneous approach having superior neutralizing activity. CHIVAX elicited systemic immunity, evidenced by specific IgG antibodies in the serum, and local mucosal immunity, indicated by IgA antibodies in saliva, nasal, and bronchoalveolar lavage secretions. Importantly, these antibodies demonstrated neutralizing activity against SARS-CoV-2 in vitro.DiscussionThe elicited antibodies recognized individual epitopes on the chimeric protein and demonstrated the capacity to block RBD-ACE2 binding of the ancestral SARS-CoV-2 strain and four VOCs. The findings provide proof of concept for using multiepitope recombinant antigens and a combined immunization protocol to induce a neutralizing immune response against SARS-CoV-2 in the pig translational model for preclinical studies

Analysis of immunization time, amplitude, and adverse events of seven different vaccines against SARS-CoV-2 across four different countries

BackgroundScarce information exists in relation to the comparison of seroconversion and adverse events following immunization (AEFI) with different SARS-CoV-2 vaccines. Our aim was to correlate the magnitude of the antibody response to vaccination with previous clinical conditions and AEFI.MethodsA multicentric comparative study where SARS-CoV-2 spike 1-2 IgG antibodies IgG titers were measured at baseline, 21-28 days after the first and second dose (when applicable) of the following vaccines: BNT162b2 mRNA, mRNA-1273, Gam-COVID-Vac, Coronavac, ChAdOx1-S, Ad5-nCoV and Ad26.COV2. Mixed model and Poisson generalized linear models were performed.ResultsWe recruited 1867 individuals [52 (SD 16.8) years old, 52% men]. All vaccines enhanced anti-S1 and anti-S2 IgG antibodies over time (p<0.01). The highest increase after the first and second dose was observed in mRNA-1273 (p<0.001). There was an effect of previous SARS-CoV-2 infection; and an interaction of age with previous SARS-CoV-2 infection, Gam-COVID-Vac and ChAdOx1-S (p<0.01). There was a negative correlation of Severe or Systemic AEFI (AEs) of naïve SARS-CoV-2 subjects with age and sex (p<0.001); a positive interaction between the delta of antibodies with Gam-COVID-Vac (p=0.002). Coronavac, Gam-COVID-Vac and ChAdOx1-S had less AEs compared to BNT162b (p<0.01). mRNA-1273 had the highest number of AEFIs. The delta of the antibodies showed an association with AEFIs in previously infected individuals (p<0.001).ConclusionsThe magnitude of seroconversion is predicted by age, vaccine type and SARS-CoV-2 exposure. AEs are correlated with age, sex, and vaccine type. The delta of the antibody response only correlates with AEs in patients previously exposed to SARS-CoV-2.Registration numberClinicalTrials.gov, identifier NCT05228912