Similar cardiometabolic effects of high- and moderate-intensity training among apparently healthy inactive adults : A randomized clinical trial

Background: Metabolic syndrome (MetS) increases the risk of morbidity and mortality from cardiovascular disease, and exercise training is an important factor in the treatment and prevention of the clinical components of MetS. Objective: The aim was to compare the effects of high-intensity interval training and steady-state moderate-intensity training on clinical components of MetS in healthy physically inactive adults. Methods: Twenty adults were randomly allocated to receive either moderate-intensity continuous training [MCT group; 60-80% heart rate reserve (HRR)] or high-intensity interval training (HIT group; 4 × 4 min at 85-95% peak HRR interspersed with 4 min of active rest at 65% peak HRR). We used the revised International Diabetes Federation criteria for MetS. A MetS Z-score was calculated for each individual and each component of the MetS. Results: In intent-to-treat analyses, the changes in MetS Z-score were 1.546 (1.575) in the MCT group and -1.249 (1.629) in the HIT group (between-groups difference, P = 0.001). The average number of cardiometabolic risk factors changed in the MCT group (-0.133, P = 0.040) but not in the HIT group (0.018, P = 0.294), with no difference between groups (P = 0.277). Conclusion: Among apparently healthy physically inactive adults, HIT and MCT offer similar cardiometabolic protection against single MetS risk factors but differ in their effect on average risk factors per subject. Trial registration ClinicalTrials.gov NCT02738385 registered on March 23, 2016 © 2017 The Author(s)

Similar cardiometabolic effects of high- and moderate-intensity training among apparently healthy inactive adults: a randomized clinical trial

Incluye fe de erratasBackground: Metabolic syndrome (MetS) increases the risk of morbidity and mortality from cardiovascular disease, and exercise training is an important factor in the treatment and prevention of the clinical components of MetS. Objective: The aim was to compare the effects of high-intensity interval training and steady-state moderate-intensity training on clinical components of MetS in healthy physically inactive adults. Methods: Twenty adults were randomly allocated to receive either moderate-intensity continuous training [MCT group; 60–80% heart rate reserve (HRR)] or high-intensity interval training (HIT group; 4 × 4 min at 85–95% peak HRR interspersed with 4 min of active rest at 65% peak HRR). We used the revised International Diabetes Federation criteria for MetS. A MetS Z-score was calculated for each individual and each component of the MetS. Results: In intent-to-treat analyses, the changes in MetS Z-score were 1.546 (1.575) in the MCT group and −1.249 (1.629) in the HIT group (between-groups difference, P = 0.001). The average number of cardiometabolic risk factors changed in the MCT group (−0.133, P = 0.040) but not in the HIT group (0.018, P = 0.294), with no difference between groups (P = 0.277). Conclusion: Among apparently healthy physically inactive adults, HIT and MCT offer similar cardiometabolic protection against single MetS risk factors but differ in their effect on average risk factors per subject.This study was part of the project entitled “Body Adiposity Index and Biomarkers of Endothelial and Cardiovascular Health in Adults” and “High Interval Intensity Training and ideal cardiovascular Heart Study (HIIT-Heart Study)”, which was funded by Centre for Studies on Measurement of Physical Activity, School of Medicine and Health Sciences, Universidad del Rosario (Code No FIUR DN-BG001)

Effect of moderate versus high intensity interval exercise training on vascular function in inactive latin-american adults: a randomized clinical trial

Exercise training is effective for improving cardiometabolic health and physical fitness in inactive adults. However, limited research has been conducted on the optimal exercise training intensity for this population. We investigate the effect of moderate versus high intensity interval exercise training on vascular function and physical fitness in physically inactive adults. Twenty inactive adults were randomly allocated to receive either moderate intensity training (MCT group) or high intensity interval training (HIT group). The MCT group performed aerobic training at an intensity of 55-75% of the walking on a treadmill at 60-80% heart rate max (HRmax) until expenditure of 300 kcal until the end of training. The HIT group performed running on a treadmill during 4 minutes at 85-95% peak HRmax and had a recovery of 4 minutes at 65% peak HRmax until expenditure of 300 kcal until the end of training. Vascular function (flow-mediated vasodilation, FMD [%], aortic pulse wave velocity, PWV [m·s−1]), blood lipids [fasting glucose, triacylglycerol, total cholesterol, LDL-cholesterol, HDL-cholesterol], blood pressure, and physical fitness (Muscle strength (handgrip [kg]), exercise capacity (V̇O2peak and graded exercise test duration [minutes]), were measured at baseline and 12-weeks thereafter. Trial registration. ClinicalTrials.gov NCT02738385, registered on 23 March 2016.Universidad del Rosari

Effect of moderate versus high intensity interval exercise training on vascular function in inactive latin-american adults: a randomized clinical trial

Exercise training is effective for improving cardiometabolic health and physical fitness in inactive adults. However, limited research has been conducted on the optimal exercise training intensity for this population. We investigate the effect of moderate versus high intensity interval exercise training on vascular function and physical fitness in physically inactive adults. Twenty inactive adults were randomly allocated to receive either moderate intensity training (MCT group) or high intensity interval training (HIT group). The MCT group performed aerobic training at an intensity of 55-75% of the walking on a treadmill at 60-80% heart rate max (HRmax) until expenditure of 300 kcal until the end of training. The HIT group performed running on a treadmill during 4 minutes at 85-95% peak HRmax and had a recovery of 4 minutes at 65% peak HRmax until expenditure of 300 kcal until the end of training. Vascular function (flow-mediated vasodilation, FMD [%], aortic pulse wave velocity, PWV [m·s−1]), blood lipids [fasting glucose, triacylglycerol, total cholesterol, LDL-cholesterol, HDL-cholesterol], blood pressure, and physical fitness (Muscle strength (handgrip [kg]), exercise capacity (V̇O2peak and graded exercise test duration [minutes]), were measured at baseline and 12-weeks thereafter. Trial registration. ClinicalTrials.gov NCT02738385, registered on 23 March 2016.Universidad del Rosari

Similar cardiometabolic effects of high- and moderate-intensity training among apparently healthy inactive adults : A randomized clinical trial

Background: Metabolic syndrome (MetS) increases the risk of morbidity and mortality from cardiovascular disease, and exercise training is an important factor in the treatment and prevention of the clinical components of MetS. Objective: The aim was to compare the effects of high-intensity interval training and steady-state moderate-intensity training on clinical components of MetS in healthy physically inactive adults. Methods: Twenty adults were randomly allocated to receive either moderate-intensity continuous training [MCT group; 60-80% heart rate reserve (HRR)] or high-intensity interval training (HIT group; 4 × 4 min at 85-95% peak HRR interspersed with 4 min of active rest at 65% peak HRR). We used the revised International Diabetes Federation criteria for MetS. A MetS Z-score was calculated for each individual and each component of the MetS. Results: In intent-to-treat analyses, the changes in MetS Z-score were 1.546 (1.575) in the MCT group and -1.249 (1.629) in the HIT group (between-groups difference, P = 0.001). The average number of cardiometabolic risk factors changed in the MCT group (-0.133, P = 0.040) but not in the HIT group (0.018, P = 0.294), with no difference between groups (P = 0.277). Conclusion: Among apparently healthy physically inactive adults, HIT and MCT offer similar cardiometabolic protection against single MetS risk factors but differ in their effect on average risk factors per subject. Trial registration ClinicalTrials.gov NCT02738385 registered on March 23, 2016 © 2017 The Author(s)

Erratum: Similar cardiometabolic effects of high- and moderate-intensity training among apparently healthy inactive adults : A randomized clinical trial

In the original version of this article [1], published on 30 May 2017, we noticed an error in Table 2. The lean mass (kg) and fat mass (%) corrected table is included in this erratum. These changes have no material impact on the conclusions of our paper. We apologize for any inconvenience caused to our readers. © The Author(s) 2017