Correlación Citocolposcópica e Histopatológica de Lesiones Pre e invasivas de Cuello Uterino en las pacientes que acuden a la Consulta Ginecológica del Centro de Salud Francisco Morazán, Managua I semestre de 2015

El presente estudio tiene como objetivo establecer la correlación citológica e histopatológica de lesiones pre e invasivas de cuello uterino en las pacientes que acuden a la consulta ginecológica del centro de salud francisco Morazán en el municipio de Managua en el I semestre 2015. Es una investigación de tipo descriptiva de corte transversal, donde la muestra fue 100 pacientes que acudieron a la consulta ginecológica de dicha unidad de salud, las cuales fueron captadas mediante información anotada en el libro de registro de citologías y biopsia que se llevaba en la unidad de salud en estudio lo que permitió identificar los expedientes de las pacientes. En los resultados encontrados se compararon las pruebas de tamizaje de PAP y colposcopia con la biopsia y se estableció el grado de correlación y por lo tanto la sensibilidad de las mismas en las diferentes lesiones. Las 100 mujeres presentaron diagnostico citológico y anatomopatológico, no así colposcópico apareciendo el diagnostico de lesión pre maligna y maligna en 54 pacientes, sin embargo todas presentaron mapeo colposcópico; se compararon las pruebas individualmente. Los grupos etarios predominantes fueron 21-30 años y 31-40 años con 31% de incidencia cada uno, la escolaridad predomino la secundaria con 45%, 73% de las participantes eran amas de casa, 47% estaban casadas, 58% inicio vida sexual antes de los 16 años. La correlación entre PAP y biopsia es baja, sin embargo es buena para detectar lesiones de alto grado; se reportó 69 casos de LIEBG por citología de los cuales se confirmaron 40 para un 57%, 22 casos de LIEAG se confirmaron por biopsia 16 para un 72.7%, 9 casos de ASCUS reportados ninguno confirmado por biopsia. Hubo buena correlación entre colposcopia y biopsia, de 26 casos de LIEBG por colposcopia 20 se confirmaron por biopsia para un 76.9%, de 27 casos de LIEAG 25 se confirmaron por biopsia para un 92.5% y 1 caso de carcinoma invasor por colposcopia el cual se confirmó por biopsi

Epidemiology and clinical characteristics of respiratory syncytial virus infections among children and adults in Mexico

BACKGROUND: Respiratory syncytial virus (RSV) is a leading etiological agent of acute respiratory tract infections and hospitalizations in children. However, little information is available regarding RSV infections in Latin American countries, particularly among adult patients. OBJECTIVE: To describe the epidemiology of RSV infection and to analyze the factors associated with severe infections in children and adults in Mexico. METHODS: Patients ≥1 month old, who presented with an influenza-like illness (ILI) to six hospitals in Mexico, were eligible for participation in the study. Multiplex reverse-transcriptase polymerase chain reaction identified viral pathogens in nasal swabs from 5629 episodes of ILI. Patients in whom RSV was detected were included in this report. RESULTS: Respiratory syncytial virus was detected in 399 children and 171 adults. RSV A was detected in 413 cases and RSV B in 163, including six patients who had coinfection with both subtypes; 414 (72.6%) patients required hospital admission, including 96 (16.8%) patients that required admission to the intensive care unit. Coinfection with one or more respiratory pathogens other than RSV was detected in 159 cases. Young age (in children) and older age (in adults) as well as the presence of some underlying conditions were associated with more severe disease. CONCLUSIONS: This study confirms that RSV is an important respiratory pathogen in children in Mexico. In addition, a substantial number of cases in adults were also detected highlighting the relevance of this virus in all ages. It is important to identify subjects at high risk of complications who may benefit from current or future preventive interventions.La Red is funded by the Mexico Ministry of Health and the U.S. National Institute of Allergy and Infectious Diseases. This project has been funded in part by funding provided by CONACYT (Fondo Sectorial SSA/IMSS/ISSSTE, Projects No. 71260 and No. 127088); National Institute of Allergy and Infectious Diseases, National Institutes of Health, through its Intramural Research Programs and a contract with Westat, Inc., Contract Number: HHSN2722009000031, Task Order Number: HHSN27200002; and through the National Cancer Institute, National Institutes of Health, under Contract No. HHSN261200800001E. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, or Westat, nor does mention of trade names, commercial products, or organizations imply endorsement by the US Government.S