55 research outputs found

    Sleep Well, Sleep Well

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    [Verse 1, English] The bells are hushed, the world is still, The sounds of toil are heard no more, the bird has ceased his tuneful song, and heav’n with stars is spangled o’er, [Chorus, English]Sleep, sleep well, sleep well, And let thy lovely eyelids close,Sleep well, sleep well, dear angel, Sweet be thy repose [Verse 2, English] Oh! Didst thou think of me today? The thought of thee my heart could fill, and now, to breathe a fond good night, beside the door I linger still, [Chorus, English] [Verse 3, English] There comes to thee from heav’nly realms A holy messenger tonight, He brings you bright and peaceful dreams, Till you awake in morning’s light. [Chorus, English] [Verse 1, German] Rings Stille herscht, es schweigt der Wald, coll en det ist des Tages Lauf der Vӧglein Lied is lӓngst verhallt am himmel ziehn die Sterne auf, [Chorus, German] Schlafe wohl, schlafe wohl, und schliess die schӧnen Augen zu, schlafe wohl, schlafe wohl, du süsser lieber Engel du [Verse 2, German] Ob du auch heut an mich gedacht? Ich dacht an dich wohl für und für und rufe jetzt dir gute Nacht” verborgen still vor deiner Thür [Chorus, German] [Verse 3, German] Es schwebe aus des Himmels Raum ein heil’ger Boto dir zur Nacht, und bringe dir den schӧnsten Traum, bis du zum Morgen neu erwacht. [Chorus, German

    Monumental heritage exposure to urban black carbon pollution

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    In this study, aerosol light-absorption measurements obtained at three sites during a winter campaign were used to analyse and identify the major sources of Black Carbon (BC) particles in and around the Alhambra monument, a UNESCO World Heritage Site that receives over 2 million visitors per year. The Conditional Bivariate Probability Function and the Aethalometer model were employed to identify the main sources of BC particles and to estimate the contributions of biomass burning and fossil fuel emissions to the total Equivalent Black Carbon (EBC) concentrations over the monumental complex. Unexpected high levels of EBC were found at the Alhambra, comparable to those measured in relatively polluted European urban areas during winter. EBC concentrations above 3.0 ÎĽg/m3, which are associated with unacceptable levels of soiling and negative public reactions, were observed at Alhambra monument on 13 days from 12 October 2015 to 29 February 2016, which can pose a risk to its long-term conservation and may cause negative social and economic impacts. It was found that road traffic emissions from the nearby urban area and access road to the Alhambra were the main sources of BC particles over the monument. However, biomass burning emissions were found to have very small impact on EBC concentrations at the Alhambra. The highest EBC concentrations were observed during an extended stagnant episode associated with persistent high-pressure systems, reflecting the large impact that can have these synoptic conditions on BC over the Alhambra.European Union's Horizon 2020 Research and Innovation Programme under grant agreement No. 654109, ACTRIS-2.Spanish Ministry of Economy and Competitiveness and FEDER through project CGL2013-45410-R, CGL2016-81092-R 598 and CGL2012-30729.Andalusia Regional Government through project P12- RNM-2409 and P12-FQM-1889

    Pre-specified matching analyses in an observational study to evaluate treatment effects in a rare disease

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    Exercise program improves therapy-related side-effects and quality of life in lymphoma patients undergoing therapy

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    Background: Exercise is beneficial and clinically meaningful for lymphoma patients undergoing therapy. It reduces side-effects of therapy such as balance control and peripheral neuropathy, subsequently improving patients' quality of life. Together with physical functioning, they are decisive factors for patients to receive their planned therapy regime, optimizing cancer control.Lymphoma patients undergoing therapy must cope with the side-effects of the disease itself, therapy and associated immobility. Peripheral neuropathy (PNP), loss of balance control and weakness not only diminishes patients' quality of life (QOL), it can also affect planning and the dosage of therapy. Exercise may enable patients to reverse these declines, improving their performance level and QOL. We carried out a randomized, controlled trial, assigning 61 lymphoma patients either to a control group (CG; N = 31) or to a 36-week intervention (IG; N = 30), consisting of sensorimotor-, endurance- and strength training twice a week. Primary end point was QOL; secondary end points included movement coordination, endurance, strength and therapy-induced side-effects. Intergroup comparison revealed improved QOL- (delta(T1-T0); P = 0.03) and PNP-related deep sensitivity in the IG: 87.5% were able to reduce the symptom, compared with 0% in the CG (P < 0.001). Significant differences in the change of balance control could be found between the groups, with the IG improving while the CG steadily declined (monopedal static delta(T3-T0); P = 0.03; dynamic delta(T3-T0); P = 0.007; perturbed mono-delta(T3-T0); P = 0.009 and bipedal delta(T3-T0); P = 0.006), failed attempts (monopedal static delta(T3-T0); P = 0.02, dynamic delta(T3-T0); P < 0.001and perturbed delta(T3-T0); P = 0.006) and improved time to regain balance (delta(T3-T0); P = 0.04). Moreover, the change in the aerobic performance level (delta(T3-T0); P = 0.05) and additional amount of exercise carried out per week [metabolic equivalent (MET); P = 0.02] differed significantly across groups. Exercise, especially sensorimotor training, is a feasible and promising method to support cancer patients during therapy. It improves patients QOL, reduces restrictions from side-effects such as PNP and improves patients' balance control, physical performance level and mobility
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