Transient current properties in electronic paper

A lot can be learned about the charge transport inside electronic paper from current measurements. Under normal conditions the current response to a voltage step decays in time. However, under some conditions the current increases before decaying to its steady state value. It is not clear why this current bump occurs for high voltages or what its properties are, based on the applied voltage. In this article we will give an explanation for the current bump, and explain its properties

Shape Memory Polymer Resonators as Highly Sensitive Uncooled Infrared Detectors

Uncooled InfraRed (IR) detectors have enabled the rapid growth of thermal imaging applications. These detectors are predominantly bolometers, where the heating of pixel from incoming IR radiation is read out as a resistance change. Another uncooled sensing method is to transduce the IR radiation into the frequency shift of a mechanical resonator. We present here a highly sensitive, simple to fabricate resonant IR sensor, based on thermo-responsive Shape Memory Polymers (SMPs). By exploiting the phase-change polymer as the transduction mechanism, our approach provides 2 orders of magnitude improvement of the temperature coefficient of frequency (TCF). The SMP has very good absorption in IR wavelengths, obviating the need for an absorber layer. A Noise Equivalent Temperature Difference (NETD) of 22 mK in vacuum and 112 mK in air are obtained using f/2 optics. Such high performance in air eliminates the need for vacuum packaging, paving a path towards flexible IR sensors

Household size and Socio-Economic Development in Kibuku District, Uganda: A Cross-sectional study.

Background of the study  The purpose of the study was to establish the effect of household size on socio-economic development in the Kibuku district by establishing the average size of households, determining the level of socio-economic development among households, and establishing the relationship between household size and socio-economic development in the Kibuku district.  Methodology: A descriptive comparative, correlational, and cross-sectional survey design was employed for this study. A sample size of 308 households was selected using the Slovene formula.  Results: Of the 300 respondents to the study, 180 were females and 120 were males. Also, 86 of the 300 selected households have 1-5 members. The findings also revealed that a big number of households in the Kibuku district depend on their parents, there were no improved medical care services, and limited to clean water in the district as surgeries and complicated health issues are carried out from the neighboring districts. Conclusion: The level of social economic development in the Kibuku district was still wanting and below the national average. There was also a significant relationship between household size and social economic status.  Recommendations Based on the findings, there is a need to sensitize the population in the Kibuku district about the use of family planning to reduce the dependence burden on household heads. Also, there is a need to awaken the government to provide social infrastructures such as electricity and tarmacked roads to increase the level of employment opportunities and household incomes of the locals

Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo

Abstract The transcription factors lymphoid enhancer binding factor 1 (LEF1) and transcription factor 7 (TCF7) (T cell factor-1 (TCF-1)) are downstream effectors of the WNT signaling pathway, which is a critical regulator of T cell development in the thymus. In this study, we show that LEF1 and TCF7 (TCF-1) are not only expressed in thymocytes, but also in mature T cells. Our data demonstrate that Ag encounter in vivo and engagement of the TCR or IL-15 receptor in vitro leads to the down-regulation of LEF1 and TCF7 (TCF-1) expression in human naive CD8 T cells. We further show that resting T cells preferentially express inhibitory LEF1 and TCF7 (TCF-1) isoforms and that T cell activation changes the isoform balance in favor of stimulatory TCF7 (TCF-1) isoforms. Altogether, our study suggests that proteins involved in the WNT signaling pathway not only regulate T cell development, but also peripheral T cell differentiation.</jats:p

Can We Avoid a Sick Fiscal Future? The Non-Sustainability of Health-Care Spending with an Aging Population

Funding for Canadian public health care has long relied on a “pay-as-you-go” funding model: for the most part, government pays for health costs each year from taxes collected in that fiscal year with effectively nothing put aside for projected rising health-care costs in the future. But the future of Canadian public health care is going to get more expensive as the relatively large cohort of baby boomers reaches retirement age. As they exit the work force, and enter the ages at which Canadians use the health-care system more, a smaller population of younger workers is going to be left paying the growing health-care costs of older Canadians. If Canadians intend to preserve a publicly funded medicare system that offers a similar level of service in the future as it does today, under the pay-as-you-go model, eventually peak taxes for Canadians born after 1988 will end up twice as high as the peak taxes that the oldest baby boomers paid. The “payas-you-go” model has become like a Ponzi scheme, where those who got in early enough make out nicely, while those who arrive late stand to suffer a serious financial blow. This should concern both Canadians who value a comprehensive public health system as well as Canadians who value competitive tax rates: There is no reason to be certain that future taxpayers will blithely accept having their taxes substantially increased to finance health care for another, older generation that did not pay for a significant portion of its own health care. If the burden proves too high for the taxpaying public to accept, that could well jeopardize Canada’s health-care system as we know it. If Canadians intend to preserve their iconic public health system, and are unprepared to unjustly overburden future generations with the tax bill left by their parents and grandparents, provincial governments must make strong and rapid efforts to reform the health system. They must find more cost-efficient ways of managing medicine, including new approaches to eldercare, chronic disease prevention and better health promotion. If policymakers respond in time with a workable strategy and adequate effort, the substantial financial health-care liability currently faced by future generations may not be eliminated entirely, but it can still be reduced dramatically

Runoff Generation from Shallow Water Table Southeastern Forested Watersheds: Unusual Behavior of Paired Watersheds Following Major Disturbance

2012 S.C. Water Resources Conference - Exploring Opportunities for Collaborative Water Research, Policy and Managemen

The long-term impact of folic acid in pregnancy on offspring DNA methylation : follow-up of the Aberdeen folic acid supplementation trial (AFAST)

Funding This work was supported by the NIHR Bristol Biomedical Research Centre at the University Hospitals Bristol NHS Foundation Trust and the University of Bristol. The views expressed in this publication are those of the authors and not necessarily those of the NHS, the National Institute for Health Research or the Department of Health. R.C.R., G.C.S., N.K., T.G., G.D.S. and C.L.R. work in a unit that receives funds from the University of Bristol and the UK Medical Research Council (MC_UU_12013/1, MC_UU_12013/2 and MC_UU_12013/8). This work was also supported by CRUK (grant number C18281/A19169) and the ESRC (grant number ES/N000498/1). C.M.T. is supported by a Wellcome Trust Career Re-entry Fellowship (grant number 104077/Z/14/Z).Peer reviewedPublisher PD