45,966 research outputs found

    A clarification of the Goodwin model of the growth cycle

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    We show that there is a difficulty in the original Goodwin model which isalso found in some more recent applications. In it both the labour share and theproportion employed can exceed unity, properties which are untenable. However, weshow that the underlying dynamic structure of the model can be reformulated toensure that these variables cannot exceed unity. An illustrative example extends theoriginal model, and we argue it is both plausible and satisfies the necessary unit boxrestrictions. We show that there is a difficulty in the original Goodwin model which isalso found in some more recent applications. In it both the labour share and theproportion employed can exceed unity, properties which are untenable. However, weshow that the underlying dynamic structure of the model can be reformulated toensure that these variables cannot exceed unity. An illustrative example extends theoriginal model, and we argue it is both plausible and satisfies the necessary unit boxrestrictions

    Fractional chemotaxis diffusion equations

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    We introduce mesoscopic and macroscopic model equations of chemotaxis with anomalous subdiffusion for modeling chemically directed transport of biological organisms in changing chemical environments with diffusion hindered by traps or macromolecular crowding. The mesoscopic models are formulated using continuous time random walk equations and the macroscopic models are formulated with fractional order differential equations. Different models are proposed depending on the timing of the chemotactic forcing. Generalizations of the models to include linear reaction dynamics are also derived. Finally a Monte Carlo method for simulating anomalous subdiffusion with chemotaxis is introduced and simulation results are compared with numerical solutions of the model equations. The model equations developed here could be used to replace Keller-Segel type equations in biological systems with transport hindered by traps, macromolecular crowding or other obstacles

    The Impact of Early Positive Results on a Mathematics and Science Partnership: The Experience of the Institute for Chemistry Literacy Through Computational Science

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    After one year of implementation, the Institute for Chemistry Literacy through Computational Science, an NSF Mathematics and Science Partnership Institute Project led by the University of Illinois at Urbana-Champaign’s Department of Chemistry, College of Medicine, and National Center for Supercomputing Applications, experienced statistically significant gains in chemistry content knowledge among students of the rural high school teachers participating in its intensive, year-round professional development course, compared to a control group. The project utilizes a two-cohort, delayed-treatment, random control trial, quasi-experimental research design with the second cohort entering treatment one year following the first. The three-year treatment includes intensive two-week summer institutes, occasional school year workshops and year-round, on-line collaborative lesson development, resource sharing, and expert support. The means of student pre-test scores for Cohort I (η=963) and Cohort II (η=862) teachers were not significantly different. The mean gain (difference between pre-test and post-test scores) after seven months in the classroom for Cohort I was 9.8 percentage points, compared to 6.7 percentage points for Cohort II. This statistically significant difference (p\u3c.001) represented an effect size of .25 standard deviation units, and indicated unusually early confirmation of treatment effects. When post-tests were compared, Cohort I students scored significantly higher than Cohort II and supported the gain score differences. The impact of these results on treatment and research plans is discussed. concentrating on the effect of lessening rural teachers’ isolation and increasing access to tools to facilitate learning

    Photoinduced Removal of Nifedipine Reveals Mechanisms of Calcium Antagonist Action on Single Heart Cells

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    The currents through voltage-activated calcium channels in heart cell membranes are suppressed by dihydropyridine calcium antagonists such as nifedipine. Nifedipine is photolabile, and the reduction of current amplitude by this drug can be reversed within a few milliseconds after a 1-ms light flash. The blockade by nifedipine and its removal by flashes were studied in isolated myocytes from neonatal rat heart using the whole-cell clamp method. The results suggest that nifedipine interacts with closed, open, and inactivated calcium channels. It is likely that at the normal resting potential of cardiac cells, the suppression of current amplitude arises because nifedipine binds to and stabilizes channels in the resting, closed state. Inhibition is enhanced at depolarized membrane potentials, where interaction with inactivated channels may also become important. Additional block of open channels is suggested when currents are carried by Ba^(2+) but is not indicated with Ca^(2+) currents. Numerical simulations reproduce the experimental observations with molecular dissociation constants on the order of 10^(-7) M for closed and open channels and 10^(-8) M for inactivated channels

    Ga^+ beam lithography for nanoscale silicon reactive ion etching

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    By using a dry etch chemistry which relies on the highly preferential etching of silicon, over that of gallium (Ga), we show resist-free fabrication of precision, high aspect ratio nanostructures and microstructures in silicon using a focused ion beam (FIB) and an inductively coupled plasma reactive ion etcher (ICP-RIE). Silicon etch masks are patterned via Ga^+ ion implantation in a FIB and then anisotropically etched in an ICP-RIE using fluorinated etch chemistries. We determine the critical areal density of the implanted Ga layer in silicon required to achieve a desired etch depth for both a Pseudo Bosch (SF_6/C_4F_8) and cryogenic fluorine (SF_6/O_2) silicon etching. High fidelity nanoscale structures down to 30 nm and high aspect ratio structures of 17:1 are demonstrated. Since etch masks may be patterned on uneven surfaces, we utilize this lithography to create multilayer structures in silicon. The linear selectivity versus implanted Ga density enables grayscale lithography. Limits on the ultimate resolution and selectivity of Ga lithography are also discussed

    Wind data from the 250-foot /76.2-meter/ tower at Wallops Island, Virginia

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    Statistical evaluation of sampled wind data from anemometers mounted on meteorological tower on Wallops Islan

    Optimal state encoding for quantum walks and quantum communication over spin systems

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    Recent work has shown that a simple chain of interacting spins can be used as a medium for high-fidelity quantum communication. We describe a scheme for quantum communication using a spin system that conserves z-spin, but otherwise is arbitrary. The sender and receiver are assumed to directly control several spins each, with the sender encoding the message state onto the larger state-space of her control spins. We show how to find the encoding that maximises the fidelity of communication, using a simple method based on the singular-value decomposition. Also, we show that this solution can be used to increase communication fidelity in a rather different circumstance: where no encoding of initial states is used, but where the sender and receiver control exactly two spins each and vary the interactions on those spins over time. The methods presented are computationally efficient, and numerical examples are given for systems having up to 300 spins.Comment: 10 pages, LaTeX, 7 EPS figures. Corrected an error in the definition and interpretation of C_B(T

    Fractional Fokker-Planck Equations for Subdiffusion with Space-and-Time-Dependent Forces

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    We have derived a fractional Fokker-Planck equation for subdiffusion in a general space-and- time-dependent force field from power law waiting time continuous time random walks biased by Boltzmann weights. The governing equation is derived from a generalized master equation and is shown to be equivalent to a subordinated stochastic Langevin equation.Comment: 5 page

    Quantum states far from the energy eigenstates of any local Hamiltonian

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    What quantum states are possible energy eigenstates of a many-body Hamiltonian? Suppose the Hamiltonian is non-trivial, i.e., not a multiple of the identity, and L-local, in the sense of containing interaction terms involving at most L bodies, for some fixed L. We construct quantum states \psi which are ``far away'' from all the eigenstates E of any non-trivial L-local Hamiltonian, in the sense that |\psi-E| is greater than some constant lower bound, independent of the form of the Hamiltonian.Comment: 4 page
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