Aerodynamic Analysis of an Arrow with Different Fletch Configurations: A Computational Approach

Archery is being contemplated from hundreds of years; however there have been not many investigations expressing and clarifying the optimal design and aerodynamic effectiveness of an Arrow. Presently Archery has turned into a significant game in Olympics. Every nation is showing colossal interest in delivering champions. So, it is important to work on the solidness of the Arrow to such an extent that its precision and aerodynamic characteristics improve. Broad examination is proceeding to work on the streamlined exhibition of the Arrow. So, this study intends to explore the aerodynamic characteristics of an Arrow for various fletches and diverse Arrow points. To accomplish this, the initial trends of aerodynamics characterization were obtained by XFLR5 v6.51 and then deep flow analysis was performed by Computational Fluid Dynamics using ANSYS Fluent. The outcomes are upon to show that the Arrow performs better at a speed range of 40-60 m/s and angles of attack from - 5 to +5 degrees. MATLAB is employed in plotting all of the non-dimensional data fluctuations, since it is the most trusted plotting software. The outcomes are validated with existing research work and significant conclusions are obtained

A single DC source generalized switched capacitors multilevel inverter with minimal component count

This paper presents a new single-source switched capacitor- (SC-) based multilevel inverter (MLI) design with a boosting potential of three times the supply voltage. To produce a waveform with seven output voltage levels, the suggested switching capacitor inverter consists of eight switches, single diode, and two capacitors. Because capacitors are inherently balanced, there is no need for a balancing circuit or sensor. The structure can be expanded using the provided generalized equations. In addition, the technique for switching control and loss analyses is explored. A fair comparison with the most recent SCMLI topologies has been conducted to demonstrate the merits of the proposed work. Furthermore, the proposed topology is evaluated using the MATLAB/SIMULINK tool, and experiments under both transient and steady-state situations are performed to demonstrate its feasibility. At dynamic-loaded situations, the performance of the proposed SCMLI with dynamic modulation index and switching frequency is tested.International Research: SA/China Joint Research Programme.https://www.hindawi.com/journals/iteesElectrical, Electronic and Computer Engineerin

An enhanced space vector PWM strategies for three phase asymmetric multilevel inverter

This work presents the two space vector pulse width modulation (SVPWM-I and SVPWM-II) strategies for eleven-level (11L) asymmetric cascaded H-bridge (CHB) multilevel inverter (MLI). Depending on the isolated structure and nonappearance of capacitor voltage balancing issues, the CHB MLI structure is favoured. These days, the SVPWM control method is accomplished superior consideration among the diverse PWM methods. In common, the SVPWM strategy is realized based on deteriorating higher-level hexagons into a lower level hexagon (2-level). Compared to the classical SVPWM strategy, the proposed SVPWM-I strategy decreases the memory and mathematical burden necessity included within the demonstration of eleven-level SVPWM devoid of losing the inverter output voltage (AC) contour by diminution the number of two-level hexagons. Also, the SVPWM-II strategy is presented, which incredibly diminishes the mathematical endeavours. The presented two SVPWM methods performed on an eleven-level asymmetric CHB multilevel inverter (MLI) by utilizing SIMULINK/MATLAB program tool and are compared with conventional sinusoidal PWM and Third harmonic injection (THI) PWM methods to confirm the proposed SVPWM methods. The proposed SVPWM methods give higher AC RMS voltage and lower harmonic distortion when compared to SPWM and THIPWM methods. To validate the presented two SVPWM control schemes, hardware results are taken on asymmetric eleven-level CHB MLI.https://www.hindawi.com/journals/iteesElectrical, Electronic and Computer Engineerin

Peripheral vasculopathy in patients with diabetic foot in tertiary care hospital

Diabetes mellitus(DM) is characterized by high blood sugar levels over a prolonged period due to alteration in either insulin secretion, insulin action, or both. Worldwide, as of the recent data collected from the World Health Organization (WHO) around 422 million adults have DM which is estimated to almost doubled by 2030 , mainly type 2 diabetes . The early detection of peripheral vascular disease in asymptomatic patients goes a long way in reduction of major and minor lower limb amputations and mortality. Hence, there is a need for evaluation of peripheral vascular disease (PVD) in all diabetics, especially those with diabetic foot by formulating effective management protocols, thereby limiting the morbidity, mortality and social costs associated with the disease. Methods: Patients who are admitted for diabetic foot ulcers between January 2017 and June 2018 in Department of General Surgery , ESIC MC & PGIMSR , Rajajinagar ,Bengaluru, India were taken for study. Results: 100 cases satisfying the inclusion criteria were taken up for the study from January 2017 to June 2018. Study population contains predominently( 68%) male patients . Out of 100 patients, 49 patients presented with pain as their most distressing symotom .Ankle brachial pressure index is less than 0.9 in 52 patiens and less than 0.3 in 06 patients. 62 Patients have documented abnormal blood flow in doppler study and CT angiogram due PVD. Most common site of block is femoropopliteal artery and collaterals are developed around the knee joint. Athersclerosis is the cause of PVD in 87% of patients.Conclusions: The prevalence of peripheral artery disease in patients with diabetic foot is significantly high i.e. 62 % as per this study. Males have a higher predilection for developing peripheral vascular disease than females. The average age of presentation of PAD in diabetics is 40 -60 years. The most common level of arterial occlusion in PAD associated diabetic foot is femoro-popliteal segment followed by tibial segment. Due to high prevalence of PVD mortality and morbidity is are significantly high these patients

High Expression of Three-Gene Signature Improves Prediction of Relapse-Free Survival in Estrogen Receptor-Positive and Node-Positive Breast Tumors

The objective of the present study was to validate prognostic gene signature for estrogen receptor alpha-positive (ERα+) and lymph node (+) breast cancer for improved selection of patients for adjuvant therapy In our previous study, we identified a group of seven genes ( GATA3, NTN4, SLC7A8, ENPP1, MLPH, LAMB2 , and PLAT) that show elevated messenger RNA (mRNA) expression levels in ERα (+) breast cancer patient samples. The prognostic values of these genes were evaluated using gene expression data from three public data sets of breast cancer patients ( n = 395). Analysis of ERα (+) breast cancer cohort ( n = 195) showed high expression of GATA3, NTN4 , and MLPH genes significantly associated with longer relapse-free survival (RFS). Next cohort of ERα (+) and node (+) samples ( n = 109) revealed high mRNA expression of GATA3, SLC7A8 , and MLPH significantly associated with longer RFS. Multivariate analysis of combined three-gene signature for ERα (+) cohort, and ERα (+) and node (+) cohorts showed better hazard ratio than individual genes. The validated three-gene signature sets for ERα (+) cohort, and ERα (+) and node (+) cohort may have potential clinical utility since they demonstrated predictive and prognostic ability in three independent public data sets

Paratesticular Osteosarcoma—A Rare Tumor with Distinctive Imaging Findings

Extraosseous osteosarcoma (EOO) is a rare mesenchymal malignancy representing 4% of all osteosarcomas and 1% of soft tissue sarcomas. The testes, its supporting structures, that is, paratestes, and the spermatic cord are among the rarest sites for EOO, with only 11 published English language reports to date. We report our experience with a 73-year-old male presenting with left hemiscrotal swelling, noted to have extensive amorphous intratumoral calcification on imaging. He underwent left high inguinal orchidectomy with en bloc hemiscrotectomy, with a final pathologic diagnosis of primary paratesticular osteosarcoma. Our literature review corroborates this distinctive, hitherto overlooked imaging feature