Expert recommendations to personalization of medical approaches in treatment of multiple sclerosis: an overview of family planning and pregnancy

Multiple sclerosis is the most common chronic autoimmune disease of the central nervous system which preferentially affects females at childbearing age. For this reason, patients and treating physicians were frequently confronted with questions concerning family planning, pregnancy and birth. Preventive and personalized treatment approaches are considered, because topics as heredity, risk of congenital malformations, influence of pregnancy on MS and aspects of drug therapy during the period of conception, pregnancy, puerperium and lactation have to be discussed. Here, we provide an overview about the current state of knowledge regarding these issues

Topological defects in antiferromagnetically coupled multilayers with perpendicular anisotropy

A rich variety of specific multidomain textures recently observed in antiferromagnetically coupled multilayers with perpendicular anisotropy include regular (equilibrium) multidomain states as well as different types of topological magnetic defects. Within a phenomenological theory we have classified and analyzed the possible magnetic defects in the antiferromagnetic ground state and determine their structures. We have derived the optimal sizes of the defects as functions of the antiferromagnetic exchange, the applied magnetic field, and geometrical parameters of the multilayer. The calculated magnetic phase diagrams show the existence regions for all types of magnetic defects. Experimental investigations of the remanent states (observed after different magnetic pre-history) in [Co/Pt]/Ru multilayers with wedged Co layers reveal a corresponding succession of different magnetic defect domain types.Comment: 3 pages, 4 figure

Using Muonic Hydrogen in Optical Spectroscopy Experiment to Detect Extra Dimensions

Considering that gravitational force might deviate from Newton's inverse-square law (ISL) and become much stronger in small scale, we propose a kind of optical spectroscopy experiment to detect this possible deviation and take electronic, muonic and tauonic hydrogen atoms as examples. This experiment might be used to indirectly detect the deviation of ISL down to nanometer scale and to explore the possibility of three extra dimensions in ADD's model, while current direct gravity tests cannot break through micron scale and go beyond two extra dimensions scenario.Comment: 9 pages, 2 figures. To appear in IJT

Relativistic Restrictions on the Distinguishability of Orthogonal Quantum States

We analyze the restrictions on the distinguishability of quantum states imposed by special relativity. An explicit expression relating the error probability for distinguishing between two orthogonal single-photon states with the time $T$ elapsed from the start of the measurement procedure until the measurement result is obtained by the observer.Comment: 9 pages, 1 figure (misprints in formulas corrected

Hysteresis loops of Co-Pt perpendicular magnetic multilayers

We develop a phenomenological model to study magnetic hysteresis in two samples designed as possible perpendicular recording media. A stochastic cellular automata model captures cooperative behavior in the nucleation of magnetic domains. We show how this simple model turns broad hysteresis loops into loops with sharp drops like those observed in these samples, and explains their unusual features. We also present, and experimentally verify, predictions of this model, and suggest how insights from this model may apply more generally.Comment: 4.5 pages, 5 figure

On relativistic elements of reality

Several arguments have been proposed some years ago, attempting to prove the impossibility of defining Lorentz-invariant elements of reality. I find that a sufficient condition for the existence of elements of reality, introduced in these proofs, seems to be used also as a necessary condition. I argue that Lorentz-invariant elements of reality can be defined but, as Vaidman pointed out, they won't satisfy the so-called product rule. In so doing I obtain algebraic constraints on elements of reality associated with a maximal set of commuting Hermitian operators.Comment: Clarifications, reference added; published versio

Universality of low-energy scattering in (2+1) dimensions

We prove that, in (2+1) dimensions, the S-wave phase shift, $\delta_0(k)$, k being the c.m. momentum, vanishes as either $\delta_0 \to {c\over \ln (k/m)} or \delta_0 \to O(k^2)$ as $k\to 0$. The constant $c$ is universal and $c=\pi/2$. This result is established first in the framework of the Schr\"odinger equation for a large class of potentials, second for a massive field theory from proved analyticity and unitarity, and, finally, we look at perturbation theory in $\phi_3^4$ and study its relation to our non-perturbative result. The remarkable fact here is that in n-th order the perturbative amplitude diverges like $(\ln k)^n$ as $k\to 0$, while the full amplitude vanishes as $(\ln k)^{-1}$. We show how these two facts can be reconciled.Comment: 23 pages, Late

Proton Zemach radius from measurements of the hyperfine splitting of hydrogen and muonic hydrogen

While measurements of the hyperfine structure of hydrogen-like atoms are traditionally regarded as test of bound-state QED, we assume that theoretical QED predictions are accurate and discuss the information about the electromagnetic structure of protons that could be extracted from the experimental values of the ground state hyperfine splitting in hydrogen and muonic hydrogen. Using recent theoretical results on the proton polarizability effects and the experimental hydrogen hyperfine splitting we obtain for the Zemach radius of the proton the value 1.040(16) fm. We compare it to the various theoretical estimates the uncertainty of which is shown to be larger that 0.016 fm. This point of view gives quite convincing arguments in support of projects to measure the hyperfine splitting of muonic hydrogen.Comment: Submitted to Phys. Rev.

Relativistic Quantum Measurements, Unruh effect and Black Holes

It is shown how the technique of restricted path integrals (RPI) or quantum corridors (QC) may be applied for the analysis of relativistic measurements. Then this technique is used to clarify the physical nature of thermal effects as seen by an accelerated observer in Minkowski space-time (Unruh effect) and by a far observer in the field of a black hole (Hawking effect). The physical nature of the "thermal atmosphere" around the observer is analysed in three cases: a) the Unruh effect, b) an eternal (Kruskal) black hole and c) a black hole forming in the process of collapse. It is shown that thermal particles are real only in the case (c). In the case (b) they cannot be distinguished from real particles but they do not carry away mass of the black hole until some of these particles are absorbed by the far observer. In the case (a) thermal particles are virtual.Comment: 24 pages (Latex), 8 EPS figures The text was edited for the new versio