Thematic Assessment Report on the Underlying Causes of Biodiversity Loss and the Determinants of Transformative Change and Options for Achieving the 2050 Vision for Biodiversity of the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (Transformative Change Assessment).

Summary for Policymakers of the Thematic Assessment Report on the Underlying Causes of Biodiversity Loss and the Determinants of Transformative Change and Options for Achieving the 2050 Vision for Biodiversity of the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services.The IPBES Transformative Change Assessment was initiated following a decision from the IPBES Plenary at its eigth session (IPBES-8, June 2021), and has been approved by the IPBES Plenary at its eleventh session (IPBES-11, Windhoek, 2024). It is composed of a Summary for Policymakers and five Chapters.IPBES is an independent intergovernmental body established by Governments in 2012, IPBES provides policymakers with objective scientific assessments about the state of knowledge regarding the planet’s biodiversity, ecosystems and the contributions they make to people, as well as options and actions to protect and sustainably use these vital natural assets.</p

‘Animals we’ve never seen before’: Historical wildlife management and Indigenous relations with beavers in the mainland Inuvialuit Settlement Region, Canada

For many Inuvialuit in north-west Canada, beavers are a pest. The anomalous status of the animal has been shaped by its role in the fur trade and by federal wildlife management. These processes drove a major shift in Inuvialuit relations with beavers over the course of the twentieth century.</p

ABSENCE OF EVIDENCE IS NO EVIDENCE OF ABSENCE

ABSENCE OF EVIDENCE IS NO EVIDENCE OF ABSENC

A RETROSPECTIVE SINGLE INSTITUTIONAL ANALYSIS OF CILENGITIDE (CGT) AND CHEMOTHERAPY FOR HEAVILY PRETREATED RECURRENT GLIOBLASTOMA MULTIFORME (GBM)

A RETROSPECTIVE SINGLE INSTITUTIONAL ANALYSIS OF CILENGITIDE (CGT) AND CHEMOTHERAPY FOR HEAVILY PRETREATED RECURRENT GLIOBLASTOMA MULTIFORME (GBM

A SERIES OF PATIENTS (PTS) WITH RECURRENT GBM (rGBM) TREATED WITH ABT-414, BEVACIZUMAB (BEV) AND CCNU

A SERIES OF PATIENTS (PTS) WITH RECURRENT GBM (rGBM) TREATED WITH ABT-414, BEVACIZUMAB (BEV) AND CCN

Long-term monitoring of mammal communities in the Peneda-Gerês National Park using camera-trap data

In the past decades, agricultural land abandonment and declining land-use intensity became common, especially in the Mediterranean countries of southern Europe. In some areas, this development opened up possibilities for rewilding and the recolonisation or expansion of large mammal populations. Yet, in some instances, co-occurrence of wild mammals and free-ranging domestic herbivores might lead to potential conflicts. It is, therefore, necessary to study the ecological interactions between wild and domestic mammal species to understand the effects of land abandonment and rewilding on biodiversity and ecosystem services. Camera traps are an effective tool for studying species interactions and occupancy dynamics as they allow for long-term monitoring with minimal interference. We conducted a long-term monitoring programme with camera traps in the Peneda-Gerês National Park in northern Portugal. The area has undergone substantial land-use changes following the abandonment of agricultural areas in the past 60 years. While agro-pastoral activities, especially the breeding of free-ranging horses and cattle, are still common in the area, the intensity of these activities has decreased significantly, promoting natural succession and an increase or return of several large mammal species in recent years. Overall, our project aims at: (1) assessing the population trends of the medium and large sized mammals in the area over time; (2) analysing the effects of passive rewilding on occurrence, abundance and behaviour; and (3) understanding potential interactions or conflicts between wild and domestic herbivores. In this publication, we present results of a primary occupancy analysis between 2015 and 2020, as well as a comparison between occupancy and density estimates for 2019.Our publication provides a dataset from long-term camera-trap monitoring in the Peneda-Gerês National Park between 2015 and 2021. We established a 16 km² grid of 64 cameras deployed yearly during the summer months. Together with this publication, we publish the data and images collected between 2015 and 2021, using both the Camtrap DP standard and the GBIF Darwin Event Core. We obtained a total of 934,810 pictures on 41,234 trap nights. The pictures were automatically grouped into sequences with each sequence representing a distinct occurrence event, resulting in 80,191 occurrences. Out of those, 14,442 contained observations of a species, while the remaining were either blank or the species was not identifiable. We only obtained the information whether a species was present or absent on a picture, disregarding the number of individuals. Most observations were of domestic cattle (Bos taurus) and horses (Equus caballus), followed by European roe deer (Capreolus capreolus) and wild boar(Sus scrofa). Further observations include red fox (Vulpes vulpes), gray wolf (Canis lupus), Eurasian badger (Meles meles), stone marten (Martes foina), common genet (Genetta genetta), Iberian ibex (Capra pyrenaica) and red deer (Cervus elaphus). We estimated occupancy and densities for the most common species. The project is on-going and additional data will be included in the future. The dataset is freely available for ecological analysis, but also for training machine-learning systems in automated image classification as all pictures have been manually classified.</p

Long-term monitoring of mammal communities in the Peneda-Gerês National Park using camera-trap data

In the past decades, agricultural land abandonment and declining land-use intensity became common, especially in the Mediterranean countries of southern Europe. In some areas, this development opened up possibilities for rewilding and the recolonisation or expansion of large mammal populations. Yet, in some instances, co-occurrence of wild mammals and free-ranging domestic herbivores might lead to potential conflicts. It is, therefore, necessary to study the ecological interactions between wild and domestic mammal species to understand the effects of land abandonment and rewilding on biodiversity and ecosystem services. Camera traps are an effective tool for studying species interactions and occupancy dynamics as they allow for long-term monitoring with minimal interference. We conducted a long-term monitoring programme with camera traps in the Peneda-Gerês National Park in northern Portugal. The area has undergone substantial land-use changes following the abandonment of agricultural areas in the past 60 years. While agro-pastoral activities, especially the breeding of free-ranging horses and cattle, are still common in the area, the intensity of these activities has decreased significantly, promoting natural succession and an increase or return of several large mammal species in recent years. Overall, our project aims at: (1) assessing the population trends of the medium and large sized mammals in the area over time; (2) analysing the effects of passive rewilding on occurrence, abundance and behaviour; and (3) understanding potential interactions or conflicts between wild and domestic herbivores. In this publication, we present results of a primary occupancy analysis between 2015 and 2020, as well as a comparison between occupancy and density estimates for 2019.Our publication provides a dataset from long-term camera-trap monitoring in the Peneda-Gerês National Park between 2015 and 2021. We established a 16 km² grid of 64 cameras deployed yearly during the summer months. Together with this publication, we publish the data and images collected between 2015 and 2021, using both the Camtrap DP standard and the GBIF Darwin Event Core. We obtained a total of 934,810 pictures on 41,234 trap nights. The pictures were automatically grouped into sequences with each sequence representing a distinct occurrence event, resulting in 80,191 occurrences. Out of those, 14,442 contained observations of a species, while the remaining were either blank or the species was not identifiable. We only obtained the information whether a species was present or absent on a picture, disregarding the number of individuals. Most observations were of domestic cattle (Bos taurus) and horses (Equus caballus), followed by European roe deer (Capreolus capreolus) and wild boar(Sus scrofa). Further observations include red fox (Vulpes vulpes), gray wolf (Canis lupus), Eurasian badger (Meles meles), stone marten (Martes foina), common genet (Genetta genetta), Iberian ibex (Capra pyrenaica) and red deer (Cervus elaphus). We estimated occupancy and densities for the most common species. The project is on-going and additional data will be included in the future. The dataset is freely available for ecological analysis, but also for training machine-learning systems in automated image classification as all pictures have been manually classified.</p

ANTI-ANGIOGENIC THERAPY FOR HIGH-GRADE GLIOMA: A META-ANALYSIS

ANTI-ANGIOGENIC THERAPY FOR HIGH-GRADE GLIOMA: A META-ANALYSI

Anti-epidermal growth factor receptor therapy for glioblastoma in adults

Anti-epidermal growth factor receptor therapy for glioblastoma in adult

Radiotherapy (RT), temozolomide (TMZ), procarbazine (PCB), and the integrin inhibitor cilengitide in patients (pis) with glioblastoma (GBM) without methylation of the MGMT gene promoter (ExCentric): Results of an Australian phase II! clinical trial

Radiotherapy (RT), temozolomide (TMZ), procarbazine (PCB), and the integrin inhibitor cilengitide in patients (pis) with glioblastoma (GBM) without methylation of the MGMT gene promoter (ExCentric): Results of an Australian phase II! clinical tria