4 research outputs found

    GeneE: gene and protein query expansion with disambiguation.

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    Item does not contain fulltextSUMMARY: When referring to genes, authors often use synonyms instead of the official gene symbols. In order to accurately retrieve as many relevant documents as possible, we have developed GeneE, a web application that expands a gene query to include all known synonyms, and adds disambiguation information for ambiguous terms, before forwarding the query to either PubMed, Google or Jane. The query expansion algorithm is also available as a web service. AVAILABILITY: http://biosemantics.org/gene

    Roberto Farias e a lógica do duplo-pensar no caso da censura ao filme Pra frente, Brasil

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    A presente pesquisa busca discutir as relações entre censura e representação cinematográfica da ditadura civil-militar brasileira nos anos finais do regime, a partir do caso do filme Pra frente, Brasil, dirigido por Roberto Farias e lançado nos cinemas do país no início de 1983. Avalia-se até que ponto o modo representativo e o discurso político adotados por Farias são condicionados pelas pressões censórias existentes no período ou expressam meramente um posicionamento político do cineasta em questão

    3D-Beacons: decreasing the gap between protein sequences and structures through a federated network of protein structure data resources.

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    While scientists can often infer the biological function of proteins from their 3-dimensional quaternary structures, the gap between the number of known protein sequences and their experimentally determined structures keeps increasing. A potential solution to this problem is presented by ever more sophisticated computational protein modeling approaches. While often powerful on their own, most methods have strengths and weaknesses. Therefore, it benefits researchers to examine models from various model providers and perform comparative analysis to identify what models can best address their specific use cases. To make data from a large array of model providers more easily accessible to the broader scientific community, we established 3D-Beacons, a collaborative initiative to create a federated network with unified data access mechanisms. The 3D-Beacons Network allows researchers to collate coordinate files and metadata for experimentally determined and theoretical protein models from state-of-the-art and specialist model providers and also from the Protein Data Bank
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