1,326 research outputs found
Vögel aus Mogontiacum : ein Keramikgefäß mit Vogelkopfprotome und eine Vogelterrakotte aus dem Umfeld der römischen Töpfereien von Mainz-Weisenau
Im Folgenden sollen zwei zoomorph gestaltete Keramiken aus dem Umfeld der römischen Töpfereien von Mainz-Weisenau vorgestellt werden. Beide Stücke wurden bereits 1965 bzw. 1972 von privater Seite geborgen und stammen aufgrund der überlieferten Fundortangaben aus dem nördlichen Teil der römischen Siedlung
An algorithm for calculating the Lorentz angle in silicon detectors
Future experiments will use silicon sensors in the harsh radiation
environment of the LHC (Large Hadron Collider) and high magnetic fields. The
drift direction of the charge carriers is affected by the Lorentz force due to
the high magnetic field. Also the resulting radiation damage changes the
properties of the drift.
In this paper measurements of the Lorentz angle of electrons and holes before
and after irradiation are reviewed and compared with a simple algorithm to
compute the Lorentz angle.Comment: 13 pages, 7 figures, final version accepted by NIMA. Mainly
clarifications included and slightly shortene
Comparison of Simulation Codes for the Beam Dynamics of Low-Energy Ions
Results are presented of the simulation of low–energy ion dynamics with three different codes: KOBRA, IGUN and CPO. To share work between different codes one needs to be confident that they agree. For test cases, good agreement was found between the codes and analytical solutions. Where possible, results have been compared to experimental data from the CERN Laser Ion Source. These simulations are in general agreement with the data of the real beam line. c The following article has been submitted to Review of Scientific Instruments. After it is published, it will be found at http://ojps.aip.org/rsio/
Common cause analysis : a review and extension of existing methods
The quantitative common cause analysis code, MOBB, is extended to include uncertainties arising from modelling uncertainties and data uncertainties. Two methods, Monte Carlo simulation and the Method-of-Moments are used to propagate uncertainties through the analysis. The two different capabilities of the code are then compared. When component failure rates are assumed lognormallv distributed, bounded lognormal (Sb) distributions are used to evaluate higher moment terms, as required by the Method-of-Moments, in order to minimize the effect of the tail of the lognormal. A code using the discrete probability distribution (DPD) method is developed for analyzing system unavailability due to common initiating events (internal and external). Sample problems demonstrating each approach are also presented
Lorentz angle measurements in irradiated silicon detectors between 77 K and 300 K
Future experiments are using silicon detectors in a high radiation
environment and in high magnetic fields. The radiation tolerance of silicon
improves by cooling it to temperatures below 180 K. At low temperatures the
mobility increases, which leads to larger deflections of the charge carriers by
the Lorentz force. A good knowledge of the Lorentz angle is needed for design
and operation of silicon detectors. We present measurements of the Lorentz
angle between 77 K and 300 K before and after irradiation with a primary beam
of 21 MeV protons.Comment: 13 pages, 9 figures, submitted to ICHEP2000, Osaka, Japa
Adherence to a procalcitonin-guided antibiotic treatment protocol in patients with severe sepsis and septic shock
Background: In randomised controlled trials, procalcitonin (PCT)-guided antibiotic treatment has been proven to significantly reduce length of antibiotic therapy in intensive care unit (ICU) patients. However, concern was raised on low protocol adherence and high rates of overruling, and thus the value of PCT-guided treatment in real clinical life outside study conditions remains unclear. In this study, adherence to a PCT protocol to guide antibiotic treatment in patients with severe sepsis and septic shock was analysed.
Methods: From 2012 to 2014, surgical ICU patients with severe sepsis or septic shock were retrospectively screened for PCT measurement series appropriate to make treatment decisions on antibiotic therapy. We compared (1) patients with appropriate PCT measurement series to patients without appropriate series; (2) patients who reached the antibiotic stopping advice threshold (PCT < 0.5 ng/mL and/or decrease to 10% of peak level) to patients who did not reach a stopping advice threshold; and (3) patients who were treated adherently to the PCT protocol to non-adherently treated patients. The groups were compared in terms of antibiotic treatment duration, PCT kinetics, and other clinical outcomes.
Results: Of 81 patients with severe sepsis or septic shock, 14 were excluded due to treatment restriction or short course in the ICU. The final analysis was performed on 67 patients. Forty-two patients (62.7%) had appropriate PCT measurement series. In patients with appropriate PCT series, median initial PCT (p = 0.001) and peak PCT levels (p < 0.001) were significantly higher compared to those with non-appropriate series. In 26 patients with appropriate series, PCT levels reached an antibiotic stopping advice. In 8 of 26 patients with stopping advice, antibiotics were discontinued adherently to the PCT protocol (30.8%). Patients with adherently discontinued antibiotics had a shorter antibiotic treatment (7d [IQR 6–9] vs. 12d [IQR 9–16]; p = 0.002). No differences were seen in terms of other clinical outcomes.
Conclusion: In patients with severe sepsis and septic shock, procalcitonin testing was irregular and adherence to a local PCT protocol was low in real clinical life. However, adherently treated patients had a shorter duration of antibiotic treatment without negative clinical outcomes. Procalcitonin peak values and kinetics had a clear impact on the regularity of PCT testing
Generic nuclear safety issues : methods of analysis
"Prepared for: Nuclear Safety Analysis Center."Includes bibliographical references (leaves 223-231
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