Los nobles contra su rey. Argumentos y motivaciones de la insubordinación nobiliaria de 1272-1273

[ES] A través de una sección específica de la Crónica de Alfonso X, se realiza un acercamiento al pensamiento político de la nobleza castellana del siglo XIII, tal y como se refleja en los acontecimientos de 1272-1273. Se sugiere: a) que el auténtico móvil no declarado de la revuelta pudo ser la oposición nobilaria -principalmente de los Lara- a las ambiciones imperiales de Alfonso X; b) que el estudio en profundidad de las reivindicaciones nobiliarias no sólo revela ambiciones e interes particularistas, sino también la existencia de concepciones sobre el reino, la sociedad y el papel de la nobleza en la misma que entran en colisión con las iniciativas articuladas desde la monarquía en los decenios precedentes.[FR] À travers l’analyse du passage de la Chronique d’Alphonse X consacré aux événements des années 1272-1273, l’on tente une approche de la pensée politique de la noblesse castillane du XIIIe siècle telle que ces événements la reflètent. L’on suggère: a) que le véritable mobile, non déclaré, de la révolte a pu être l’opposition nobiliaire -principalement des Lara- aux ambitions impériales d’Alphonse X; b) que l’étude approfondie des revendications nobiliaires ne révèle pas seulement des ambitions et des intérêts particuliers, mais encore l’existence d’idées sur le royaume, la société et le rôle de la noblesse dans celle-ci qui se heurtent aux initiatives monarchiques des décennies antérieures.Peer reviewe

Influence of hematocrit on hemostasis in continuous venovenous hemofiltration during acute renal failure

Influence of hematocrit on hemostasis in continuous venovenous hemofiltration during acute renal failure.BackgroundHematocrit plays a major role in primary hemostasis by influencing blood viscosity and platelet adhesion. During continuous venovenous hemofiltration (CVVH), it is suspected that an increased hematocrit is accompanied by an activation of hemostasis and frequently leads to thromboses in the extracorporeal system. In order to examine this hypothesis, we studied the influence of hematocrit on hemostasis during CVVH.MethodsFourteen patients (8 men and 6 women, mean age 65 ± 10 years) with acute renal failure undergoing CVVH were prospectively enrolled. Polysulfone hemofilters (AV 600®; Fresenius, Oberursel, Germany) were used in all of the patients; blood flow rates were adjusted to 120 ml/min. No blood products and coagulation-related medication, except unfractionated heparin, were applied. Study exclusion criteria included a history of thromboembolism and artificial heart valves. Hemostasis activation markers (fibrinopeptide A, thrombin-antithrombin III complex, β-thromboglobulin, platelet retention) and hematocrit values were determined before and at three-day intervals during the course of CVVH treatment.ResultsThe mean hematocrit value ( ± sem) was 29 ± 1% (range, 22 to 35%). Patients with hematocrit values of less than 30% (N = 7) were compared with patients with higher hematocrit values (>30%, N = 7). The patients with a lower hematocrit (<30%) showed a stronger activation of hemostasis during CVVH when compared with those with a higher hematocrit (>30%), as indicated by a tendency toward higher values for fibrinopeptide A (25 ± 8 vs. 14 ± 5 ng/ml, P = 0.35), thrombin-antithrombin III complex (15 ± 4 vs. 10 ± 2 ng/ml, P = 0.66), and a higher β-thromboglobulin/creatinine ratio (0.62 ± 0.17 vs. 0.48 ± 0.12, P = 0.8).ConclusionContrary to our hypothesis, hematocrit values of more than 30% are not accompanied by an increased hemostasis activation during CVVH. Concerning hemostasis activation, hematocrit values between 30 and 35% may be suitable for patients on CVVH

Блок измерения объёма подземных полостей в горнодобывающей промышленности

Выпускная квалификационная работа 77 с., 13 рис., 23 табл., 19 источника, 2 прил. Объектом исследования является блок измерения объема подземных полостей в горнодобывающей промышленности. Цель работы: разработка блока измерения объема подземных полостей в горнодобывающей промышленности. В процессе исследования проводились: литературный обзор, разработка структурной и принципиальной схем устройства, разработка алгоритма вычисления объема фигур неправильной формы, написание программы для микроконтроллера. В результате исследования: был спроектирован блок измерения объема подземных полостей. Основные конструктивные, технологические и технико-эксплуатационные характеристики: Режим работы – непрерывный;Final qualifying work 77 p., 13 fig., 23 tab., 19 sources, 2 adj. The object of this study is to measure the volume flow of underground cavities in the mining industry. Objective: Development of unit volume measurement of underground cavities in the mining industry. The study was conducted with a literature review, the development of the structural and fundamental unit circuits, the development of the algorithm for calculating the volume of irregularly shaped pieces, writing a program for the microcontroller. As a result of the study: it was designed unit measuring the volume of underground cavities. The basic constructive, technological and technical and operational characteristics: operating mode - continuous

Концепция бережливого производства как инструмент повышения эффективности деятельности МЦ «Профессор»

Разработка рекомендаций по повышению эффективности деятельности медицинского центра на основе бережливого производства.Development of recommendations for improved performance of the medical centre based on lean production

Biotic interactions as mediators of context-dependent biodiversity-ecosystem functioning relationships

Biodiversity drives the maintenance and stability of ecosystem functioning as well as many of nature’s benefits to people, yet people cause substantial biodiversity change. Despite broad consensus about a positive relationship between biodiversity and ecosystem functioning (BEF), the underlying mechanisms and their context-dependencies are not well understood. This proposal, submitted to the European Research Council (ERC), aims at filling this knowledge gap by providing a novel conceptual framework for integrating biotic interactions across guilds of organisms, i.e. plants and mycorrhizal fungi, to explain the ecosystem consequences of biodiversity change. The overarching hypothesis is that EF increases when more tree species associate with functionally dissimilar mycorrhizal fungi. Taking a whole-ecosystem perspective, we propose to explore the role of tree-mycorrhiza interactions in driving BEF across environmental contexts and how this relates to nutrient dynamics. Given the significant role that mycorrhizae play in soil nutrient and water uptake, BEF relationships will be investigated under normal and drought conditions. Resulting ecosystem consequences will be explored by studying main energy channels and ecosystem multifunctionality using food web energy fluxes and by assessing carbon storage. Synthesising drivers of biotic interactions will allow us to understand context-dependent BEF relationships. This interdisciplinary and integrative project spans the whole gradient from local-scale process assessments to global relationships by building on unique experimental infrastructures like the MyDiv Experiment, iDiv Ecotron and the global network TreeDivNet, to link ecological mechanisms to reforestation initiatives. This innovative combination of basic scientific research with real-world interventions links trait-based community ecology, global change research and ecosystem ecology, pioneering a new generation of BEF research and represents a significant step towards implementing BEF theory for human needs

Position Measurements with Micro-Channel Plates and Transmission lines using Pico-second Timing and Waveform Analysis

The anodes of Micro-Channel Plate devices are coupled to fast transmission lines in order to reduce the number of electronics readout channels, and can provide two-dimension position measurements using two-ends delay timing. Tests with a laser and digital waveform analysis show that resolutions of a few hundreds of microns along the transmission line can be reached taking advantage of a few pico-second timing estimation. This technique is planned to be used in Micro-channel Plate devices integrating the transmission lines as anodes