Physical oceanography

The physical oceanography component of the AMLR program provides information on the hydrography of the upper water column with the objective of assessing its influence on the observed distribution of krill (Euphausia superba). By making closely spaced CTD/rosette casts, the water masses of the Elephant Island region can be identified, and the mean current flow deduced. This component also records the meteorological and sea surface conditions continuously while the Surveyor is in the study region to study the effect of atmospheric conditions on the upper-water-layer structure. AMLR 1992 is the third field season for the collaboration of physical measurements with biological studies.Marine Scienc

P 419 Comparison of tight junctions permeability and modulation in iris pigment epithelium and retinal pigment epithelium in vitro

Amb una superfície: 0,61 ha, de basalt i aigua nebulitzada.Barragán, Pedro (dissenyador)Gran pla general de El Volcà,conegut com la Carbonera. El carbó calent era mullat per aigua subterrània i desprenia vapor. Actualment està inactiu. Destaquen el pg. Josep Carner amb el monument a Colom i els edificis de Capitania i Duana

Algal dynamics in tropical riverine water holes

Microalgae are key components of many aquatic food webs and of aquatic biodiversity, yet little is known of the dynamics of algal assemblages in tropical systems, where diversity is likely to be very high. This study investigated algal assemblages of remnant riparian water holes in the seasonal Australian tropics, and the natural and human influences on them. Phytoplankton and water sample sand in situ physico-chemical data were collected from sites in the Burdekin River catchment, one of the largest in tropical Australia. Sites in the catchment were chosen based on differing water chemistry and turbidity. Samples were collected at three times during the day (dawn, midday, afternoon) in two microhabitats within the waterhole (open water and macrophytes) at varying times within the year representing the wet and dry seasons and the change between seasons. Multivariate analyses demonstrated compositional differences between assemblages between seasons and rivers and showed that conductivity and turbidity were major physico-chemical determinants of the differences. Majority of the sites showed dominance in Chlorophyta, followed by Cyanophyta and Heterokontophyta (Bacillariophyceae). The differences related both to natural geological and edaphic factors and to land management regimes in the catchment. The results provide improved understanding of algal dynamics in seasonal tropical rivers and will be used to create models for site-specific assessment of water quality in a regional monitoring program

Can guided introspection help avoid rationalization of meat consumption? Mixed-methods results of a pilot experimental study

The need for reducing meat consumption in affluent countries is increasingly recognized as crucial to minimizing carbon footprint. However, confronting individuals with rational arguments can prompt emotional discomfort, which is often relieved by engaging in rationalization processes stabilizing current consumption patterns. Mindfulness research suggests that making people aware of their emotional reactions through introspection can reduce these rationalization processes. In this mixed-method pilot experimental study, we inquired whether a single guided introspection, inspired by the micro-phenomenological interview technique, can alter individuals' experience of and abilities to deal with cognitive dissonance. Furthermore, we asked if such an intervention can stimulate attitude or intention changes concerning meat consumption. After inducing cognitive dissonance by exposing participants to pictures of the slaughter of a cow, the intervention group (n = 36) participated in the guided introspection, while the control group (n = 39) played solitaire. Self-report questionnaire measures of emotional discomfort, rationalization strategies, and attitudes towards meat consumption were administered before and after the intervention. Also, open-ended responses to participants’ experience of the study were analyzed. Quantitative results show significantly lower negative attitudes toward reducing meat consumption in the intervention group compared to the control group (partial 2 = 0.107). Qualitative results indicate that these participants are more aware of negative emotions while engaging less in rationalization strategies. We conclude that our study indicates some potential for guided introspection to affect dissonance resolution and provide suggestions for future research

Chronicles of Oklahoma

Article describes the growth and development of the tobacco industry among the Cherokees, the history of the tobacco trade in Indian Territory, and the conflict that occurred when the government tried to levy tobacco taxes over the Cherokee Nation

Biological processing of dinuclear ruthenium complexes in eukaryotic cells

The biological processing - mechanism of cellular uptake, effects on the cytoplasmic and mitochondrial membranes, intracellular sites of localisation and induction of reactive oxygen species - of two dinuclear polypyridylruthenium(ii) complexes has been examined in three eukaryotic cells lines. Flow cytometry was used to determine the uptake of [{Ru(phen)2}2{μ-bb12}](4+) (Rubb12) and [Ru(phen)2(μ-bb7)Ru(tpy)Cl](3+) {Rubb7-Cl, where phen = 1,10-phenanthroline, tpy = 2,2':6',2''-terpyridine and bbn = bis[4(4'-methyl-2,2'-bipyridyl)]-1,n-alkane} in baby hamster kidney (BHK), human embryonic kidney (HEK-293) and liver carcinoma (HepG2) cell lines. The results demonstrated that the major uptake mechanism for Rubb12 and Rubb7-Cl was active transport, although with a significant contribution from carrier-assisted diffusion for Rubb12 and passive diffusion for Rubb7-Cl. Flow cytometry coupled with Annexin V/TO-PRO-3 double-staining was used to compare cell death by membrane damage or apoptosis. Rubb12 induced significant direct membrane damage, particularly with HepG2 cells, while Rubb7-Cl caused considerably less membrane damage but induced greater levels of apoptosis. Confocal microscopy, coupled with JC-1 assays, demonstrated that Rubb12 depolarises the mitochondrial membrane, whereas Rubb7-Cl had a much smaller affect. Cellular localisation experiments indicated that Rubb12 did not accumulate in the mitochondria, whereas significant mitochondrial accumulation was observed for Rubb7-Cl. The effect of Rubb12 and Rubb7-Cl on intracellular superoxide dismutase activity showed that the ruthenium complexes could induce cell death via a reactive oxygen species-mediated pathway. The results of this study demonstrate that Rubb12 predominantly kills eukaryotic cells by damaging the cytoplasmic membrane. As this dinuclear ruthenium complex has been previously shown to exhibit greater toxicity towards bacteria than eukaryotic cells, the results of the present study suggest that metal-based cationic oligomers can achieve selective toxicity against bacteria, despite exhibiting a non-specific membrane damage mechanism of action.Xin Li, Kirsten Heimann, Xuyen Thi Dinh, F. Richard Keene and J. Grant Collin

Neonatal non-contact respiratory monitoring based on real-time infrared thermography

<p>Abstract</p> <p>Background</p> <p>Monitoring of vital parameters is an important topic in neonatal daily care. Progress in computational intelligence and medical sensors has facilitated the development of smart bedside monitors that can integrate multiple parameters into a single monitoring system. This paper describes non-contact monitoring of neonatal vital signals based on infrared thermography as a new biomedical engineering application. One signal of clinical interest is the spontaneous respiration rate of the neonate. It will be shown that the respiration rate of neonates can be monitored based on analysis of the anterior naris (nostrils) temperature profile associated with the inspiration and expiration phases successively.</p> <p>Objective</p> <p>The aim of this study is to develop and investigate a new non-contact respiration monitoring modality for neonatal intensive care unit (NICU) using infrared thermography imaging. This development includes subsequent image processing (region of interest (ROI) detection) and optimization. Moreover, it includes further optimization of this non-contact respiration monitoring to be considered as physiological measurement inside NICU wards.</p> <p>Results</p> <p>Continuous wavelet transformation based on Debauches wavelet function was applied to detect the breathing signal within an image stream. Respiration was successfully monitored based on a 0.3°C to 0.5°C temperature difference between the inspiration and expiration phases.</p> <p>Conclusions</p> <p>Although this method has been applied to adults before, this is the first time it was used in a newborn infant population inside the neonatal intensive care unit (NICU). The promising results suggest to include this technology into advanced NICU monitors.</p

Diagnostic and Therapeutic Challenges

This case is submitted by Drs. Salvador Pastor-Idoate, Manchester Royal Eye Hospital, and Manchester Vision Regeneration (MVR) Lab at NIHR/Wellcome Trust, Manchester CRF, United Kingdom; Heinrich Heimann, Royal Liverpool and Broadgreen University Hospitals NHS Trust; Pearse A. Keane, Moorfields Eye Hospital, London, United Kingdom, and Konstantinos Balaskas; Manchester Royal Eye Hospital, Manchester, United Kingdom; commented by Dr. Brandon J. Lujan, Portland, Oregon

Urbanization impacts on the climate in Europe: Numerical experiments by the PSU-NCAR Mesoscale Model (MM5)

The objective of this study is to investigate the effects of urban land on the climate in Europe on local and regional scales. Effects of urban land cover on the climate are isolated using the fifth-generation Pennsylvania State University-National Center for Atmospheric Research (PSU-NCAR) Mesoscale Model (MM5) with a modified land surface scheme based on the Town Energy Budget model. Two model scenarios represent responses of climate to different states of urbanization in Europe: 1) no urban areas and 2) urban land in the actual state in the beginning of the twenty-first century. By comparing the simulations of these contrasting scenarios, spatial differences in near-surface temperature and precipitation are quantified. Simulated near-surface temperatures and an urban heat island for January and July over a period of 6 yr (2000-05) agree well with corresponding measurements at selected urban areas. The conversion of rural to urban land results in statistically significant changes to precipitation and near-surface temperature over areas of the land cover perturbations. The diurnal temperature range in urbanized regions was reduced on average by 1.26 degrees +/- 0.71 degrees C in summer and by 0.73 degrees +/- 00.54 degrees C in winter. Inclusion of urban areas results in an increase of urban precipitation in winter (0.09 +/- 00.16 mm day(-1)) and a precipitation reduction in summer (-0.05 +/- 0.22 mm day(-1)). [References: 49

G-CREWE: Graph CompREssion With Embedding for Network Alignment

Network alignment is useful for multiple applications that require increasingly large graphs to be processed. Existing research approaches this as an optimization problem or computes the similarity based on node representations. However, the process of aligning every pair of nodes between relatively large networks is time-consuming and resource-intensive. In this paper, we propose a framework, called G-CREWE (Graph CompREssion With Embedding) to solve the network alignment problem. G-CREWE uses node embeddings to align the networks on two levels of resolution, a fine resolution given by the original network and a coarse resolution given by a compressed version, to achieve an efficient and effective network alignment. The framework first extracts node features and learns the node embedding via a Graph Convolutional Network (GCN). Then, node embedding helps to guide the process of graph compression and finally improve the alignment performance. As part of G-CREWE, we also propose a new compression mechanism called MERGE (Minimum dEgRee neiGhbors comprEssion) to reduce the size of the input networks while preserving the consistency in their topological structure. Experiments on all real networks show that our method is more than twice as fast as the most competitive existing methods while maintaining high accuracy.Comment: 10 pages, accepted at the 29th ACM International Conference onInformation and Knowledge Management (CIKM 20