A technique for making clean holes in metallic piping and components

Testing was conducted to develop a technique of providing clean holes in process piping or in a metal surface accessible from one side only without disassembling the system. The method was performed on sample pieces of piping and worked successfully with no contaminants being found on the inside of the pipe. The materials tested were Inconel 600, 304 stainless steel, Hastelloy X, and ASTM-A53 black steel. The technique was developed such that it could be done in the field with hand-held power tools and a portable tungsten inert gas welding machine

Performance and evaluation of two liquid-metal pumps for sodium-potassium service

Performance tests on liquid metal pumps for sodium potassium loop

Atomistic studies of transformation pathways and energetics in plutonium

One of the most challenging problems in understanding the structural phase transformations in Pu is to determine the energetically favored, continuous atomic pathways from one crystal symmetry to another. This problem involves enumerating candidate pathways and studying their energetics to garner insight into instabilities and energy barriers. The purpose of this work is to investigate the energetics of two transformation pathways for the delta to alpha' transformation in Pu that were recently proposed [Lookman et al., Phys. Rev. Lett. 100:145504, 2008] on the basis of symmetry. These pathways require the presence of either an intermediate hexagonal closed-packed (hcp) structure or a simple hexagonal (sh) structure. A subgroup of the parent fcc and the intermediate hexagonal structure, which has trigonal symmetry, facilitates the transformation to the intermediate hcp or sh structure. Phonons then break the translational symmetry from the intermediate hcp or sh structure to the final monoclinic symmetry of the alpha' structure. We perform simulations using the modified embedded atom method (MEAM) for Pu to investigate these candidate pathways. Our main conclusion is that the path via hcp is energetically favored and the volume change for both pathways essentially occurs in the second step of the transformation, i.e. from the intermediate sh or hcp to the monoclinic structure. Our work also highlights the deficiency of the current state-of-the-art MEAM potential in capturing the anisotropy associated with the lower symmetry monoclinic structure.Comment: 12 pages, 5 figures, accepted for publication in Philos. Ma

The effects of donepezil in Alzheimer's disease - Results from a multinational trial

Donepezil has been shown to be well tolerated and to improve cognition and global function in patients with mild to moderately severe Alzheimer's disease (AD). The current trial was undertaken to investigate further the efficacy and safety of donepezil, in a multinational setting, in patients with mild to moderately severe AD. This 30-week, placebo-controlled, parallel-group study consisted of a 24-week, double-blind treatment phase followed by a 6-week, single-blind, placebo washout. Eight hundred and eighteen patients with mild to moderately severe AD were randomly allocated to treatment with single, daily doses of 5 or 10 mg donepezil, or placebo. The two primary efficacy measures were: a cognitive performance test, the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) and a global evaluation, the Clinician's Interview-Based Impression of Change with caregiver input (CIBIC plus). Secondary outcome measures included the Sum of the Boxes of the Clinical Dementia Rating Scale (CDR-SB), a modified Interview for Deterioration in Daily living activities in Dementia (IDDD) and a patient-rated quality of life assessment. Statistically significant improvements in cognitive and global function were observed, as evaluated by ADAS-cog and CIBIC plus, respectively, in both the 5 and 10 mg/day donepezil groups, compared with placebo. Treatment-associated changes were also observed in functional skills, as shown by improved scores on the CDR-SB and the complex-tasks component of the IDDD. A dose-response effect was evident, with the 10 mg/day donepezil group demonstrating greater benefits in all outcome measures than the 5 mg/day group. Donepezil was well tolerated by this patient population and did not produce any clinically significant laboratory test abnormalities. The results of this study confirm that donepezil is effective and well tolerated in treating the symptoms of mild to moderately severe AD

ECSA Special Issue

Over 500 delegates took part in the third international ECSA conference in September 2020. Across 30 sessions, as well as keynote talks, e-poster presentations and more informal settings, they discussed and debated a diverse range of subjects related to citizen science. This special edition of ‘JCOM’ brings together some of the central themes that were under the spotlight at ECSA 2020. Since ECSA 2020 has been one of the first examples of a conference that moved completely online, and it has been considered a big success, we also include the Conference Report, as supplementary material with this editorial

Interdisciplinary Innovation and Vision in the HVAC

High energy costs in buildings are forcing the building owners, developers, fund and facility managers to find alternate energy efficiency methods while improving the indoor air quality and thus the comfort level of the room occupants. High potentials for optimizing costs can be found in the HVAC systems when calculated over the total Life-Cycle-Cost (LCC) of a building incorporating planning through to facility management. This requires an accurate plan specifying an efficient technical operating method with optimized energy cost efficiency and comfort for the room occupants. In turn, the plan should be considered in any bidding process. Multisensory equipment is an integral part of the LCC concept and should not be underestimated in its impact on energy efficiency. The possibility of customizing the requirements of the room occupants should be included in each specification of a building/room automation system. The following case study will explain how modern sensory systems can be used for investment and energy savings in various HVAC system

Hyperfine, rotational and Zeeman structure of the lowest vibrational levels of the 87^{87}Rb2_2 \tripletex state

We present the results of an experimental and theoretical study of the electronically excited \tripletex state of $^{87}$Rb$_2$ molecules. The vibrational energies are measured for deeply bound states from the bottom up to $v'=15$ using laser spectroscopy of ultracold Rb$_2$ Feshbach molecules. The spectrum of each vibrational state is dominated by a 47\,GHz splitting into a \cog and \clg component caused mainly by a strong second order spin-orbit interaction. Our spectroscopy fully resolves the rotational, hyperfine, and Zeeman structure of the spectrum. We are able to describe to first order this structure using a simplified effective Hamiltonian.Comment: 10 pages, 7 figures, 2 table

Visual Analytics for Understanding Spatial Situations from Episodic Movement Data

Continuing advances in modern data acquisition techniques result in rapidly growing amounts of geo-referenced data about moving objects and in emergence of new data types. We define episodic movement data as a new complex data type to be considered in the research fields relevant to data analysis. In episodic movement data, position measurements may be separated by large time gaps, in which the positions of the moving objects are unknown and cannot be reliably reconstructed. Many of the existing methods for movement analysis are designed for data with fine temporal resolution and cannot be applied to discontinuous trajectories. We present an approach utilizing Visual Analytics methods to explore and understand the temporal variation of spatial situations derived from episodic movement data by means of spatio-temporal aggregation. The situations are defined in terms of the presence of moving objects in different places and in terms of flows (collective movements) among the places. The approach, which combines interactive visual displays with clustering of the spatial situations, is presented by example of a real dataset collected by Bluetooth sensors