266 research outputs found

    Off-Campus Student Life Survey

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    In Spring quarter of academic year 2011-2012, 3,571 students at Western Washington University were emailed to solicit their participation in the Off-Campus WWU Student Life Survey. This survey was sponsored by the Campus Community Coalition and was intended to generate a more accurate picture of the experiences of Western students living off-campus in Bellingham. One thousand twenty four students (28.7%) responded and 901 (25.2%) completed the survey in its entirety. Sixty seven percent of respondents were female, 80% (712) of students self-identified as Caucasian/white and 42.8% were seniors. Eight hundred and forty six (94%) of respondents indicated they were renters. The Off-Campus Student Life Survey consisted of 67 questions in either open or closed choice format. Questions addressed the topics of: neighborhood experience, housing condition, knowledge of legal rights, experience with maintenance and requests for repairs, party etiquette, knowledge of community resources, and respondent demographics. The goals of this project were to gain a better understanding of what students do not know about their legal rights and responsibilities so that university and community groups can better work to educate students, to collect data on landlord/tenant legal issues that could help inform city policy makers, to give students a chance to voice their opinions in a constructive way, and to encourage them to seek out assistance for any issues they have regarding housing

    Classification of a Haemophilus influenzae ABC Transporter HI1470/71 through Its Cognate Molybdate Periplasmic Binding Protein, MoIA

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    molA (HI1472) from H. influenzae encodes a periplasmic binding protein (PBP) that delivers substrate to the ABC transporter MolB_2C_2 (formerly HI1470/71). The structures of MolA with molybdate and tungstate in the binding pocket were solved to 1.6 and 1.7 Å resolution, respectively. The MolA-binding protein binds molybdate and tungstate, but not other oxyanions such as sulfate and phosphate, making it the first class III molybdate-binding protein structurally solved. The ~100 ÎŒM binding affinity for tungstate and molybdate is significantly lower than observed for the class II ModA molybdate-binding proteins that have nanomolar to low micromolar affinity for molybdate. The presence of two molybdate loci in H. influenzae suggests multiple transport systems for one substrate, with molABC constituting a low-affinity molybdate locus

    ‘I mean family doesn't have to be mom and dad
. It's the people who are there for you. The people who are there for you when you've fallen and you can't get up’: An exploration of the meaning of family for care-experienced young people

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    Young people who experience out-of-home care have typically encountered difficult and / or disrupted family relationships. This article reports on a survey undertaken in the USA with 215 young adults (aged 18 and 22) who experienced out-of-home care starting in preadolescence. The paper examines responses to an open-ended interview question, “How do you define family?”. The analysis highlighted that few young people define family as confined to blood relations. More commonly, young people adopted more flexible definitions, prioritising the ‘doing’ and ‘feeling’ of family, over biological connections. Moreover, the propensity for young people to reflect on their conceptions of family and attempt to “do family” differently from what they had experienced was also evident. The findings encourage consideration of the utility of family as an important concept for child welfare practice, as positive and flexible understandings of family were imbued with a sense of agency, identity, belonging and overall well-being. Key messages (if applicable): (Summarising the main messages from the paper in up to four bullet points) 1. Care experienced young people conceptualise family in different ways 2. Care experienced young people may have ambivalent feeling about birth family and may need help to work through this. 3. Care experienced young people need opportunities to make and deepen friendships. 4. Practitioners should actively destigmatise conceptualisations of family that differ from traditional notions

    Using the Traditional Ex Vivo Whole Blood Model to Discriminate Bacteria by Their Inducible Host Responses

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    Whole blood models are rapid and versatile for determining immune responses to inflammatory and infectious stimuli, but they have not been used for bacterial discrimination. Staphylococcus aureus, S. epidermidis and Escherichia coli are the most common causes of invasive disease, and rapid testing strategies utilising host responses remain elusive. Currently, immune responses can only discriminate between bacterial ‘domains’ (fungi, bacteria and viruses), and very few studies can use immune responses to discriminate bacteria at the species and strain level. Here, whole blood was used to investigate the relationship between host responses and bacterial strains. Results confirmed unique temporal profiles for the 10 parameters studied: IL-6, MIP-1α, MIP-3α, IL-10, resistin, phagocytosis, S100A8, S100A8/A9, C5a and TF3. Pairwise analysis confirmed that IL-6, resistin, phagocytosis, C5a and S100A8/A9 could be used in a discrimination scheme to identify to the strain level. Linear discriminant analysis (LDA) confirmed that (i) IL-6, MIP-3α and TF3 could predict genera with 95% accuracy; (ii) IL-6, phagocytosis, resistin and TF3 could predict species at 90% accuracy and (iii) phagocytosis, S100A8 and IL-10 predicted strain at 40% accuracy. These data are important because they confirm the proof of concept that host biomarker panels could be used to identify bacterial pathogens
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