Maori facial tattoo (Ta Moko): implications for face recognition processes.

Ta Moko is the art of the Maori tattoo. It was an integral aspect of Maori society and is currently seeing resurgence in popularity. In particular it is linked with ancestry and a sense of “Maori” pride. Ta Moko is traditionally worn by Maori males on the buttocks and on the face, while Maori women wear it on the chin and lips. With curvilinear lines and spiral patterns applied to the face with a dark pigment, the full facial Moko creates a striking appearance. Given our reliance on efficiently encoding faces this transformation could potentially interfere with how viewers normally process and recognise the human face (e.g. configural information). The pattern’s effects on recognising identity, expression, race, speech, and gender are considered, and implications are drawn, which could help wearers and viewers of Ta Moko understand why sustained attention (staring) is drawn to such especially unique faces

Phonics instruction and early reading: Professional views from the classroom

Debates about the most effective ways of teaching early readers have raged for more than half a century. In recent years, government in the UK and in some other English-speaking countries has promoted the teaching of “synthetic phonics” as the key to success in training young readers. Schools were offered government funding to buy approved materials and a new, statutory phonics screening 'check' for all children in Year 1 was introduced. This check was widely criticised, and the governmental instruction to use synthetic phonics as the core reading method met considerable opposition from the profession. To discern the reasons for these concerns, and their validity, the UK National Association for the Teaching of English conducted an on-line survey of teachers' views and practices in relation to the teaching and assessment of early reading. 445 respondents completed the survey. They were asked what weight they placed on phonics when assessing overall reading levels; whether the teaching of phonics impacted on the ways they taught reading and writing, and on the teaching of other subjects; and the impact (if any) that the increased focus on the teaching of phonics had had on comprehension, higher order reading skills, writing and spelling. Other questions included the provision of pupil support and the focus of any school inspection recently experienced. Finally - after giving their views on the purposes of the phonics check and on the way the results should be communicated to parents - respondents were offered an opportunity to communicate any further thoughts or concerns about these issues. A detailed account of these responses is followed by a discussion and evaluation of what they reveal about current practice in teaching early reading in the UK

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

SummaryBackground Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatoryactions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19.Methods In this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19Therapy [RECOVERY]), several possible treatments were compared with usual care in patients admitted to hospitalwith COVID-19 in the UK. The trial is underway at 176 hospitals in the UK. Eligible and consenting patients wererandomly allocated to either usual standard of care alone or usual standard of care plus azithromycin 500 mg once perday by mouth or intravenously for 10 days or until discharge (or allocation to one of the other RECOVERY treatmentgroups). Patients were assigned via web-based simple (unstratified) randomisation with allocation concealment andwere twice as likely to be randomly assigned to usual care than to any of the active treatment groups. Participants andlocal study staff were not masked to the allocated treatment, but all others involved in the trial were masked to theoutcome data during the trial. The primary outcome was 28-day all-cause mortality, assessed in the intention-to-treatpopulation. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936.Findings Between April 7 and Nov 27, 2020, of 16 442 patients enrolled in the RECOVERY trial, 9433 (57%) wereeligible and 7763 were included in the assessment of azithromycin. The mean age of these study participants was65·3 years (SD 15·7) and approximately a third were women (2944 [38%] of 7763). 2582 patients were randomlyallocated to receive azithromycin and 5181 patients were randomly allocated to usual care alone. Overall,561 (22%) patients allocated to azithromycin and 1162 (22%) patients allocated to usual care died within 28 days(rate ratio 0·97, 95% CI 0·87–1·07; p=0·50). No significant difference was seen in duration of hospital stay (median10 days [IQR 5 to >28] vs 11 days [5 to >28]) or the proportion of patients discharged from hospital alive within 28 days(rate ratio 1·04, 95% CI 0·98–1·10; p=0·19). Among those not on invasive mechanical ventilation at baseline, nosignificant difference was seen in the proportion meeting the composite endpoint of invasive mechanical ventilationor death (risk ratio 0·95, 95% CI 0·87–1·03; p=0·24).Interpretation In patients admitted to hospital with COVID-19, azithromycin did not improve survival or otherprespecified clinical outcomes. Azithromycin use in patients admitted to hospital with COVID-19 should be restrictedto patients in whom there is a clear antimicrobial indication

Measuring a Journey without Goal: Meditation, Spirituality, and Physiology

The secular practice of meditation is associated with a range of physiological and cognitive effects, including lower blood pressure, lower cortisol, cortical thickening, and activation of areas of the brain associated with attention and emotion regulation. However, in the context of spiritual practice, these benefits are secondary gains, as the primary aim is spiritual transformation. Despite obvious difficulties in trying to measure a journey without goal, spiritual aspects involved in the practice of meditation should also be addressed by experimental study. This review starts by considering meditation in the form of the relaxation response (a counterpart to the stress response), before contrasting mindfulness research that emphasizes the role of attention and alertness in meditation. This contrast demonstrates how reference to traditional spiritual texts (in this case Buddhist) can be used to guide research questions involving meditation. Further considerations are detailed, along with the proposal that research should triangulate spiritual textual sources, first person accounts (i.e., neurophenomenology), and physiological/cognitive measures in order to aid our understanding of meditation, not only in the secular context of health benefits, but also in the context of spiritual practice