Stop Signal課題における運動抑制の脳内機構に関する研究

京都大学0048新制・課程博士博士(医学)甲第16363号医博第3615号新制||医||989(附属図書館)28994京都大学大学院医学研究科医学専攻(主査)教授 河野 憲二, 教授 金子 武嗣, 教授 村井 俊哉学位規則第4条第1項該当Doctor of Medical ScienceKyoto UniversityDA

Interhemispheric Resting-State Functional Connectivity Predicts Severity of Idiopathic Normal Pressure Hydrocephalus

La auditoría contable interna es una actividad independiente de supervisión, cuyo fin es mejorar las operaciones de una empresa. Esta consultoría realizada de manera objetiva, ayuda a una organización a cumplir sus metas mediante un enfoque sistemático, que permite mejorar la eficacia de los procesos. La presente investigación se desarrolló con el fin de determinar la influencia de la auditoría contable interna en las finanzas de las empresas textiles del sector de Gamarra, para ello se aplicó una encuesta a 132 contadores, empresarios y profesionales dedicados a la administración en 12 empresas de Gamarra, mientras que la casuística de desarrollo de una auditoría contable interna se realizó en la empresa Textiles El Rosario S.A. La investigación realizó una revisión de las normas aplicables a la práctica de la auditoría, tales como: Las Normas Internacionales de Auditoría (NIAS), las Normas de Auditoría Generalmente Aceptadas (NAGAS) y las Normas Internacionales para el Ejercicio de la Auditoría Interna (IIA). Esta información determinó que la auditoría interna genera un valor agregado en la compañía, ayudando desde el inicio para poder planear la visión, misión de la empresa y sus objetivos estratégicos, minimizando el riesgo y mejorando la competitividad ante sus competidores. En la actualidad, la globalización permite que las empresas penetren en mercados internacionales, por ello a través de esta investigación se demuestra la importancia de una auditoría interna realizada de manera objetiva y con un dictamen veraz, que permita a las medianas empresas del sector de Gamarra su crecimiento, a través del manejo eficiente de sus finanzas, el cumplimiento de los objetivos propuestos y el fortalecimiento del control interno.The internal accounting audit is an independent supervisory activity; whose purpose is to improve the operations of a company. This consultancy carried out in an objective manner, helps an organization to achieve its goals through a systematic approach, which allows improving the efficiency of the processes. The present investigation was developed with the purpose of determining the influence of the internal accounting audit in the finances of the textile companies of the sector of Gamarra, for it a survey was applied to 132 accountants, businessmen and professionals dedicated to the administration in 12 companies of Gamarra, while the casuistry of the development of an internal accounting audit was carried out in the company Textiles El Rosario SA The investigation conducted a review of the rules applicable to the practice of the audit, such as: International Auditing Standards (NIAS), Generally Accepted Auditing Standards (NAGAS) and International Standards for the Exercise of Internal Audit (IIA ). This information determined that the internal audit generates added value in the company, helping from the beginning to be able to plan the vision, mission of the company and its strategic objectives, minimizing the risk and improving the competitiveness before its competitors. Currently, globalization allows companies to penetrate international markets, so this research demonstrates the importance of an internal audit conducted objectively and with a truthful opinion, allowing medium-sized companies in the Gamarra sector its growth, through the efficient management of its finances, the fulfillment of the proposed objectives and the strengthening of internal control.Tesi

Disseminated Nocardia farcinica infection in a patient with myasthenia gravis successfully treated by linezolid: a case report and literature review.

Nocardiosis is increasingly being diagnosed because of a growing population of immunocompromised hosts and improvements in the detection of Nocardia species in clinical laboratories. Historically, sulphonamides have been the first-line therapy for the treatment of nocardiosis, but sulphonamides tend to have a high rate of drug allergy in clinical settings. In this report, we described a disseminated Nocardia farcinica infection that occurred in a patient with myasthenia gravis who suffered from multiple drug allergies and was successfully treated using linezolid. We undertook a review of the literature of previously reported cases of nocardiosis treated with linezolid. To date, only 15 cases of nocardiosis treated with linezolid have been published. All cases exhibited long-term tolerance of linezolid, and 14 of 15 cases showed either an improvement in or complete clearance of the infection. According to the literature review, linezolid is an attractive alternative to trimethoprim-sulfamethoxazole for the treatment of disseminated nocardiosis, despite limited clinical evidence to support this claim