1,355 research outputs found

    Self-Assembly of Patchy Particles into Polymer Chains: A Parameter-Free Comparison between Wertheim Theory and Monte Carlo Simulation

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    We numerically study a simple fluid composed of particles having a hard-core repulsion, complemented by two short-ranged attractive (sticky) spots at the particle poles, which provides a simple model for equilibrium polymerization of linear chains. The simplicity of the model allows for a close comparison, with no fitting parameters, between simulations and theoretical predictions based on the Wertheim perturbation theory, a unique framework for the analytic prediction of the properties of self-assembling particle systems in terms of molecular parameter and liquid state correlation functions. This theory has not been subjected to stringent tests against simulation data for ordering across the polymerization transition. We numerically determine many of the thermodynamic properties governing this basic form of self-assembly (energy per particle, order parameter or average fraction of particles in the associated state, average chain length, chain length distribution, average end-to-end distance of the chains, and the static structure factor) and find that predictions of the Wertheim theory accord remarkably well with the simulation results

    Photoionization of Galactic Halo Gas by Old Supernova Remnants

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    We present new calculations on the contribution from cooling hot gas to the photoionization of warm ionized gas in the Galaxy. We show that hot gas in cooling supernova remnants (SNRs) is an important source of photoionization, particularly for gas in the halo. We find that in many regions at high latitude this source is adequate to account for the observed ionization so there is no need to find ways to transport stellar photons from the disk. The flux from cooling SNRs sets a floor on the ionization along any line of sight. Our model flux is also shown to be consistent with the diffuse soft X-ray background and with soft X-ray observations of external galaxies. We consider the ionization of the clouds observed towards the halo star HD 93521, for which there are no O stars close to the line of sight. We show that the observed ionization can be explained successfully by our model EUV/soft X-ray flux from cooling hot gas. In particular, we can match the H alpha intensity, the S++/S+ ratio, and the C+* column. From observations of the ratios of columns of C+* and either S+ or H0, we are able to estimate the thermal pressure in the clouds. The slow clouds require high (~10^4 cm^-3 K) thermal pressures to match the N(C+*)/N(S+) ratio. Additional heating sources are required for the slow clouds to maintain their ~7000 K temperatures at these pressures, as found by Reynolds, Hausen & Tufte (1999).Comment: AASTeX 5.01; 34 pages, 2 figures; submitted to Astrophysical Journa

    Universal Statistical Behavior of Neural Spike Trains

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    We construct a model that predicts the statistical properties of spike trains generated by a sensory neuron. The model describes the combined effects of the neuron's intrinsic properties, the noise in the surrounding, and the external driving stimulus. We show that the spike trains exhibit universal statistical behavior over short times, modulated by a strongly stimulus-dependent behavior over long times. These predictions are confirmed in experiments on H1, a motion-sensitive neuron in the fly visual system.Comment: 7 pages, 4 figure

    Photoluminescence of High Quality Epitaxial p-type InN

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    Indium nitride (InN) is a group III-V semiconductor that is part of the Al,Ga:N family. It is an infrared bandgap semiconductor with great potential for use in photovoltaic applications. Being an intrinsically n-type material, p-type doping is naturally one of the ongoing hot topics in InN research, which is of interest in the fabrication of pn junctions. Plasma-assisted molecular beam epitaxy (PAMBE) grown Mg doped InN thin film was investigated via systematic optical characterizations. Photoluminescence (PL) measurement has been a key part of the research, exhibiting a wide range of spectral lines between 0.54 and 0.67 eV. In a critical Mg concentration range of 2.6×10¹⁷ and 1.0×10¹⁸ cm⁻³, a strong luminescence line at 0.6 eV has been associated with a Mg-related deep acceptor. Correspondingly, a variable magnetic field Hall (VFH) effect measurement has successfully probed a buried hole-mediated conductivity path underneath a surface electron accumulation layer. This specific doping range also led to a manifestation of a “true” band-to-band transition at 0.67 eV. Such an observation has not previously been reported for InN and in our case this assignment is convincingly supported by the quadratic characteristic of the excitation power law. This established that a rigorous control of Mg flux can sufficiently compensate the background electron concentration of InN via the substitutional incorporation on In sites (Mg_In). However, introduction of donor-like complexes somewhat suppressed this process if too much Mg or even alternative dopants such as Zn and Mn were used. Also distinctively observed was a strongly quenched PL quantum efficiency from heavily doped films, where time-resolved differential transmission (TRDT) measurement showed a biexponential carrier lifetime decay curve owing to the onset of Auger recombination processes. These observations certainly have profound implications for devices and beyond

    Rapid, sensitive, type specific PCR detection of the E7 region of human papillomavirus type 16 and 18 from paraffin embedded sections of cervical carcinoma

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    Human papillomavirus (HPV) infection, and in particularly infection with HPVs 16 and 18, is a central carcinogenic factor in the uterine cervix. We established and optimized a PCR assay for the detection and discrimination of HPV types 16 and 18 in archival formaldehyde fixed and paraffin embedded (FFPE) sections of cervical cancer

    Textures And Traction: How Tube-Dwelling Polychaetes Get A Leg Up

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    By controlling the traction between its body and the tube wall, a tube-dwelling polychaete can move efficiently from one end of its tube to the other, brace its body during normal functions (e.g., ventilation and feeding), and anchor within its tube avoiding removal by predators. To examine the potential physical interaction between worms and the tubes they live in, scanning electron microscopy was used to reveal and quantify the morphology of worm bodies and the tubes they produce for species representing 13 families of tube-dwelling polychaetes. In the tubes of most species there were macroscopic or nearly macroscopic (~10 μm–1 mm) bumps or ridges that protruded slightly into the lumen of the tube; these could provide purchase as a worm moves or anchors. At this scale (~10 μm-1 mm), the surfaces of the chaetal heads that interact with the tube wall were typically small enough to fit within spaces between these bumps (created by the inward projection of exogenous materials incorporated into the tube wall) or ridges (made by secretions on the interior surface of the tube). At a finer scale (0.01–10 μm), there was a second overlap in size, usually between the dentition on the surfaces of chaetae that interact with the tube walls and the texture provided by the secreted strands or microscopic inclusions of the inner linings. These linings had a surprising diversity of micro-textures. The most common micro-texture was a “fabric” of secreted threads, but there were also orderly micro-ridges, wrinkles, and rugose surfaces provided by microorganisms incorporated into the inner tube lining. Understanding the fine structures of tubes in conjunction with the morphologies of the worms that build them gives insight into how tubes are constructed and how worms live within them

    Ensaio regional de linhagens de arroz irrigado do Programa de Melhoramento Genético da Embrapa no RS - safra 2008/09.

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    O Ensaio Regional de linhagens de arroz irrigado visa selecionar genótipos que apresentem alta adaptabilidade e estabilidade aos diversos ambientes em que são cultivadas e que expressem elevado rendimento de grãos, associado à características agronômicas, industriais e culinárias adequadas. Este experimento teve como objetivo avaliar linhagens do programa da Embrapa no Ensaio Regional de Rendimento

    Gaps in detailed knowledge of human papillomavirus (HPV) and the HPV vaccine among medical students in Scotland

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    <p>Background: A vaccination programme targeted against human papillomavirus (HPV) types16 and 18 was introduced in the UK in 2008, with the aim of decreasing incidence of cervical disease. Vaccine roll out to 12–13 year old girls with a catch-up programme for girls aged up to 17 years and 364 days was accompanied by a very comprehensive public health information (PHI) campaign which described the role of HPV in the development of cervical cancer.</p> <p>Methods: A brief questionnaire, designed to assess acquisition of knowledge of HPV infection and its association to cervical cancer, was administered to two different cohorts of male and female 1st year medical students (school leavers: 83% in age range 17–20) at a UK university. The study was timed so that the first survey in 2008 immediately followed a summer's intensive PHI campaign and very shortly after vaccine roll-out (150 students). The second survey was exactly one year later over which time there was a sustained PHI campaign (213 students).</p> <p>Results: We addressed three research questions: knowledge about three specific details of HPV infection that could be acquired from PHI, whether length of the PHI campaign and/or vaccination of females had any bearing on HPV knowledge, and knowledge differences between men and women regarding HPV. No female student in the 2008 cohort had completed the three-dose vaccine schedule compared to 58.4% of female students in 2009. Overall, participants’ knowledge regarding the sexually transmitted nature of HPV and its association with cervical cancer was high in both year groups. However, in both years, less than 50% of students correctly identified that HPV causes over 90% of cases of cervical cancer. Males gave fewer correct answers for these two details in 2009. In 2008 only around 50% of students recognised that the current vaccine protects against a limited subset of cervical cancer-causing HPV sub-types, although there was a significant increase in correct response among female students in the 2009 cohort compared to the 2008 cohort.</p> <p>onclusions: This study highlights a lack of understanding regarding the extent of protection against cervical cancer conferred by the HPV vaccine, even among an educated population in the UK who could have a vested interest in acquiring such knowledge. The intensive PHI campaign accompanying the first year of HPV vaccination seemed to have little effect on knowledge over time. This is one of the first studies to assess detailed knowledge of HPV in both males and females. There is scope for continued improvements to PHI regarding the link between HPV infection and cervical cancer.</p&gt
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