256 research outputs found
Historical review of Polish copyright legislation and recent developments of permitted use in educational establishments
This thesis was submitted for the degree of Master of Law and awarded by Brunel University.This dissertation examines the Polish Copyright legislation and recent developments of permitted use in educational establishments through a historical perspective. It focuses on legal history, codification processes and ways of unification reviewed in the context of successive periods during 1795-2012. The main issue being considered within this field of law is permitted use and its educational application. The dissertation seeks to answer the question whether developments in the scope of permitted use have been influenced by historical events and advancements in the education sector. It explores and analyzes those factors that help find a balance between providing wide access to educational materials, thus securing sustained input to education, as well as the authorsâ rights to protect their works and creativity. The dissertation shows how the implementation of permitted use provisions in Polish education has traditionally been influenced by historical circumstances, national legal traditions and technological advancements in education, including publishing of educational materials. Permitted use has become increasingly significant as a result of the educational establishmentsâ dynamic progress during the political and societal transformation of the 1990s. Further, the dissertation defines the scope of permitted use implemented in educational establishments in Poland, discussing the factors that shape it and the extent that educational institutions are entitled to benefit from permitted use regulations. It assesses the impact of permitted use on schoolbook publishing by examining two cases studies, schoolbooks published by Ossolineum in the 1930s, and the âSwitch on Polandâ online schoolbook project of 2011. An evaluation of Polish permitted use regulations and comparison with those of the UK, France and Germany is provided. Polish permitted use regulations are further examined vis-Ă -vis the EU Information Society Directive (ISD, 2001/29/EC). There is no single or unified approach emerging as defining permitted use for educational purposes. Differences are identified in both understanding and balancing the societal need of accessing knowledge through education with protecting author copyright and creativity. This diversity of law flexibility among European countries, its implementation and current limitations occur as a result of different historical circumstances and societal needs shaping the scope of permitted use
Survivors of Aortic Dissection: Activity, Mental Health, and Sexual Function
BackgroundCurrently no research exists assessing lifestyle modifications and emotional state of acute aortic dissection (AAD) survivors. We sought to assess activity, mental health, and sexual function in AAD survivors.HypothesisPhysical and sexual activity will decrease in AAD survivors compared to preâdissection. Incidence of anxiety and depression will be significant after AAD.MethodsA cross sectional survey was mailed to 197 subjects from a single academic medical center (part of larger IRAD database). Subjects were â„18 years of age surviving a type A or B AAD between 1996 and 2011. 82 surveys were returned (overall response rate 42%).ResultsMean age ± SD was 59.5 ± 13.7 years, with 54.9% type A and 43.9% type B patients. Walking remained the most prevalent form of physical activity (49 (60%) preâdissection and 47 (57%) postâdissection). Physical inactivity increased from 14 (17%) before AAD to 20 (24%) after AAD; sexual activity decreased from 31 (38%) to 9 (11%) mostly due to fear. Most patients (66.7%) were not exerting themselves physically or emotionally at AAD onset. Systolic blood pressure (SBP) at 36 months postâdischarge for patients engaging in â„2 sessions of aerobic activity/week was 126.67 ± 10.30 vs. 141.10 ± 11.87 (pâvalue 0.012) in those who did not. Selfâreported newâonset depression after AAD was 32% and also 32% for newâonset anxiety.ConclusionsAlterations in lifestyle and emotional state are frequent in AAD survivors. Clinicians should screen for unfounded fears or beliefs after dissection that may reduce function and/or quality of life for AAD survivors.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/116073/1/clc22418_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/116073/2/clc22418.pd
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Making sense of evidence in management decisions: the role of research-based knowledge on innovation adoption and implementation in health care
Background: Although innovation can improve patient care, implementing new ideas is often challenging. Previous research found that professional attitudes, shaped in part by health policies and organisational cultures, contribute to differing perceptions of innovation âevidenceâ. However, we still know little about how evidence is empirically accessed and used by organisational decision-makers when innovations are introduced.
Aims and objectives: We aimed to investigate the use of different sources and types of evidence in innovation decisions to answer the following questions: how do managers make sense of evidence? What role does evidence play in management decision-making when adopting and implementing innovations in health care? How do wider contextual conditions and intraorganisational capacity influence research use and application by health-care managers?
Methods: Our research design comprised multiple case studies with mixed methods. We investigated technology adoption and implementation in nine acute-care organisations across England. We employed structured survey questionnaires, in-depth interviews and documentary analysis. The empirical setting was infection prevention and control. Phase 1 focused on the espoused use of evidence by 126 non-clinical and clinical hybrid managers. Phase 2 explored the use of evidence by managers in specific technology examples: (1) considered for adoption; (2) successfully adopted and implemented; and (3) rejected or discontinued.
Findings: (1) Access to, and use of, evidence types and sources varied greatly by profession. Clinicians reported a strong preference for science-based, peer-reviewed, published evidence. All groups called upon experiential knowledge and expert opinion. Nurses overall drew upon a wider range of evidence sources and types. Non-clinical managers tended to sequentially prioritise evidence on cost from national-level sources, and local implementation trials. (2) A sizeable proportion of professionals from all groups, including experienced staff, reported difficulty in making sense of evidence. Lack of awareness of existing implementation literature, lack of knowledge on how to translate information into current practice, and lack of time and relevant skills were reported as key reasons for this. (3) Infection outbreaks, financial pressures, performance targets and trusted relationships with suppliers seemed to emphasise a pragmatic and less rigorous approach in sourcing for evidence. Trust infrastructure redevelopment projects, and a strong emphasis on patient safety and collaboration, appeared to widen scope for evidence use. (4) Evidence was continuously interpreted and (re)constructed by professional identity, organisational role, team membership, audience and organisational goals. (5) Doctors and non-clinical managers sourced evidence plausible to self. Nursing staff also sought acceptance of evidence from other groups. (6) We found diverse âevidence templatesâ in use: âbiomedical-scientificâ, âpractice-basedâ, ârational-policyâ. These represented shared cognitive models which defined what constituted acceptable and credible evidence in decisions. Nurses drew on all diverse âtemplatesâ to make sense of evidence and problems; non-clinical managers drew mainly on the practice-based and rational-policy templates; and doctors drew primarily on the biomedical-scientific template.
Conclusions: An evidence-based management approach that inflexibly applies the principles of evidence-based medicine, our findings suggest, neglects how evidence is actioned in practice and how codified research knowledge inter-relates with other âevidenceâ also valued by decision-makers. Local processes and professional and microsystem considerations played a significant role in adoption and implementation. This has substantial implications for the effectiveness of large-scale projects and systems-wide policy
Laparoscopic Liver Resection for Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC), remains one of the most common causes of cancer-related death globally. HCC typically arises in the setting of chronic liver disease and cirrhosis and as such, treatment must be balanced between the biology of the tumor, underlying liver function and performance status of the patient. Hepatic resection is the procedure of choice in patients with high-performance status who harbor a solitary mass (regardless of size). Before the first laparoscopic hepatectomy (LH) was described as early as 1991, open hepatectomy (OH) was the only choice for surgical treatment of liver tumors. LH indications were initially based solely on tumor location, size, and type and was only used for partial resection of the anterolateral segments. Since then, LH has been shown to share the benefits of other laparoscopic procedures, such as earlier recovery and discharge, and reduced postoperative pain; these are obtained with no differences in oncologic outcomes compared to open resection. Specific to liver resection, LH can limit the volume of intraoperative blood loss, shorten portal clamp time and decrease overall and liver-specific complications. This chapter will offer an overview of standard steps are in pursuing laparoscopic liver resection, be it for a minor segmentectomy or a lobectomy
Exercise and Physical Activity for the PostâAortic Dissection Patient: The Clinician's Conundrum
Despite the paucity of evidence, it is often presumed, and is physiologically plausible, that sudden, acute elevations in blood pressure may transiently increase the risk of recurrent aortic dissection (AD) or rupture in patients with a prior AD, because a postâdissection aorta is almost invariably dilated and may thus experience greater associated wall stress as compared with a nondilated aorta. Few data are available regarding the specific types and intensities of exercise that may be both safe and beneficial for this escalating patient population. The purpose of this editorial/commentary is to further explore this conundrum for clinicians caring for and counseling AD survivors. Moderateâintensity cardiovascular activity may be cardioprotective in this patient cohort. It is likely that severe physical activity restrictions may reduce functional capacity and quality of life in postâAD patients and thus be harmful, underscoring the importance of further exploring the role of physical activity and/or structured exercise in this atârisk patient population.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/116077/1/clc22481_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/116077/2/clc22481.pd
Aortic dissection type I in a weightlifter with hypertension: A case report
Acute aortic dissection can occur at the time of intense physical exertion in strength-trained athletes like weightlifters, bodybuilders, throwers, and wrestlers
Lymphovascular and perineural invasion as selection criteria for adjuvant therapy in intrahepatic cholangiocarcinoma: a multi-institution analysis
AbstractObjectivesCriteria for the selection of patients for adjuvant chemotherapy in intrahepatic cholangiocarcinoma (IHCC) are lacking. Some authors advocate treating patients with lymph node (LN) involvement; however, nodal assessment is often inadequate or not performed. This study aimed to identify surrogate criteria based on characteristics of the primary tumour.MethodsA total of 58 patients who underwent resection for IHCC between January 2000 and January 2010 at any of three institutions were identified. Primary outcome was overall survival (OS).ResultsMedian OS was 23.0months. Median tumour size was 6.5cm and the median number of lesions was one. Overall, 16% of patients had positive margins, 38% had perineural invasion (PNI), 40% had lymphovascular invasion (LVI) and 22% had LN involvement. A median of two LNs were removed and a median of zero were positive. Lymph nodes were not sampled in 34% of patients. Lymphovascular and perineural invasion were associated with reduced OS [9.6months vs. 32.7months (P= 0.020) and 10.7months vs. 32.7months (P= 0.008), respectively]. Lymph node involvement indicated a trend towards reduced OS (10.7months vs. 30.0months; P= 0.063). The presence of either LVI or PNI in node-negative patients was associated with a reduction in OS similar to that in node-positive patients (12.1months vs. 10.7months; P= 0.541). After accounting for adverse tumour factors, only LVI and PNI remained associated with decreased OS on multivariate analysis (hazard ratio4.07, 95% confidence interval 1.60â10.40; P= 0.003).ConclusionsLymphovascular and perineural invasion are separately associated with a reduction in OS similar to that in patients with LN-positive disease. As nodal dissection is often not performed and the number of nodes retrieved is frequently inadequate, these tumour-specific factors should be considered as criteria for selection for adjuvant chemotherapy
The true prognosis of resected distal cholangiocarcinoma
International audienceBACKGROUND: Prognosis of distal cholangiocarcinoma (DCC) after pancreaticoduodenectomy (PD) remains poorly assessed. The aims of this study were to describe the oncological results of PD in DCC and to compare its prognosis to pancreatic ductal adenocarcinoma (PDAC). METHODS: All PD for periampullary carcinoma performed between January 2000 and March 2013 were extracted from a prospective database. Risk factors likely to influence overall (OS) and disease-free (DFS) survivals of DCC were assessed by multivariable analyses. The DCC and PDAC prognoses were compared after matching using propensity score (nearest neighbor matching). RESULTS: Of the 290 patients analyzed, 56 had DCC, with a mean age of 65â±â15 years. The median OS was 36.9 months. Recurrence occurred in 35 patients (67%), mostly in the liver (37%). The median DFS was 14.6 months. Combined organ resection was an independent risk factor for worse OS and DFS (Pâ=â0.01 and Pâ=â0.001, respectively). Matching analysis found no significant difference between DCC and PDAC in terms of OS (Pâ=â0.284) or DFS (Pâ=â0.438). CONCLUSION: This first propensity analysis demonstrated that DCC and PDAC have the same prognosis, linked to the high rate of early recurrence, particularly associated with the need for combined organ resection. J. Surg. Oncol. © 2016 Wiley Periodicals, In
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