Sustainable nano-sodium silicate and silver nitrate impregnated locally made ceramic filters for point-of-use water treatments in sub-Sahara African households

The poor access to water quality for Nigerians has pushed for the designing of new trend silver nitrate impregnated locally made Point-Of-Use (POU) ceramic filters to enhance water purification efficiency for household use. This study utilized silver nitrate-molded ceramic filters prepared with Kaolin from Owode, silt soil, sodium silicate, sawdust, and distilled water in three varying proportions to ascertain pollution removal efficiencies. Heating was carried out by firing the filters at 900 �C and further preheating at 400 �C after dipping in silver nitrate solution. Silver nanoparticle and dissociated particle discharge from filter pot painted with 0.03 mg/g caseincovered nAg or AgNO3 were estimated as an element of pH (5–9), ionic strength (1–50mM), and cation species (Naþ, Ca2þ, Mg2þ). Silver delivery was constrained by disintegration as Agþ and resulting cation exchange measures, paying little heed to silver structure applied. Water analysis for both heavy metals (Pb and Cd) and microbial load (E. coli) evaluated, corroborate the maximum removal efficiency. It was observed that kaolinsawdust with the Silver nitrate filters showed a constant and effective removal of both heavy metals and disinfection of microbial loads. The minimum flow rates observed were 4.97 mL/min for batch filter used for Iju River water sample one (AF1) and 4.98 mL/min for batch filter used for Iju River water sample two (AF2) having porosity 49.05% and 50.00%, whereas the 5 mL/min higher flow rate was used for batch filter from borehole water sample one (BF1) and batch filter used for well water sample two (CF2) with porosity of 50.00%. Significantly, the results obtained show that the filters are suitable for point-of-use application in both the urban and rural areas of developing countries such as Nigeri

Anatomic localization of O6-methylguanine DNA methyltransferase (MGMT) promoter methylated and unmethylated tumors: a radiographic study in 358 de novo human glioblastomas.

Promoter methylation of O6-methylguanine DNA methyltransferase (MGMT) is associated with a favorable prognosis in glioblastoma multiforme (GBM) and has been hypothesized to occur early in tumor transformation of glial cells. Thus, a possible link exists between the site of malignant transformation and MGMT promoter methylation status. Using the Analysis of Differential Involvement (ADIFFI) statistical mapping technique in a total of 358 patients with GBM, we demonstrate that human de novo GBMs occur in a high frequency contiguous with the posterior subventricular zone (SVZ); MGMT promoter methylated GBMs are lateralized to the left hemisphere, while MGMT unmethylated GBMs are lateralized to the right hemisphere; and tumors near the left temporal lobe have a significantly longer overall survival compared with tumors occurring elsewhere, independent of treatment or MGMT methylation status

Anatomic localization of O6-methylguanine DNA methyltransferase (MGMT) promoter methylated and unmethylated tumors: a radiographic study in 358 de novo human glioblastomas.

Promoter methylation of O6-methylguanine DNA methyltransferase (MGMT) is associated with a favorable prognosis in glioblastoma multiforme (GBM) and has been hypothesized to occur early in tumor transformation of glial cells. Thus, a possible link exists between the site of malignant transformation and MGMT promoter methylation status. Using the Analysis of Differential Involvement (ADIFFI) statistical mapping technique in a total of 358 patients with GBM, we demonstrate that human de novo GBMs occur in a high frequency contiguous with the posterior subventricular zone (SVZ); MGMT promoter methylated GBMs are lateralized to the left hemisphere, while MGMT unmethylated GBMs are lateralized to the right hemisphere; and tumors near the left temporal lobe have a significantly longer overall survival compared with tumors occurring elsewhere, independent of treatment or MGMT methylation status

Synthesis and characterization of water-soluble dendronized chitosan using newkome-type dendrons

With increasing emphasis on environmental care 7 and use of renewable resources, simple and effective dendroniza- 8 tion processes were performed to obtain chitosan derivatives. We 9 present different alternatives for the modification of chitosan: 10 dendronization with a biocompatible dendron; a quaternization 11 process with an ammonium salt, which confers a permanent 12 positive charge to the polymer; and a combination of method- 13 ologies allowing amphiphilic polymers. This process confers 14 unique multivalent properties to the native chitosan, and further 15 modifications reach multivalent water-soluble polymers. Hence, 16 the most important highlight of this work is the use of renewable 17 natural polymers and the different methodologies applied to nontoxic solvents with low temperatures. The process described in 18 this paper represents a sustainable alternative for obtaining a functionalized material with properties suitable for application in 19 different areas, such as biomedicine or environmental remediation.Fil: Rimondino, Guido Noé. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Strumia, Miriam Cristina. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Martinelli, Marisa. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin