17 research outputs found

    A Systems Engineering Framework for Bioeconomic Transitions in a Sustainable Development Goal Context

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    To address sustainable development goals (SDGs), national and international strategies have been increasingly interested in the bioeconomy. SDGs have been criticized for lacking stakeholder perspectives and agency, and for requiring too little of business. There is also a lack of both systematic and systemic frameworks for the strategic planning of bioeconomy transitions. Using a systems engineering approach, we seek to address this with a process framework to bridge bioeconomy transitions by addressing SDGs. In this methodology paper, we develop a systems archetype mapping framework for sustainable bioeconomy transitions, called MPAST: Mapping Problem Archetypes to Solutions for Transitions. Using this framework with sector-specific stakeholder data facilitates the establishment of the start (problem state) and end (solution state) to understand and analyze sectorial transitions to the bioeconomy. We apply the MPAST framework to the case of a Norwegian agricultural bioeconomy transition, using data from a survey of the Norwegian agricultural sector on transitioning to a bioeconomy. The results of using this framework illustrate how visual mapping methods can be combined as a process, which we then discuss in the context of SDG implementation.A Systems Engineering Framework for Bioeconomic Transitions in a Sustainable Development Goal ContextpublishedVersio

    Toward an integrated project complexity narrative – A case study of academic organizations

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    The last decade has seen a growing interest in the benefits of applying project management (PM) and system engineering (SE) in an integrated way toward complex projects and programs. The concept of project complexity dimensions, with roots in both disciplines, is suggested as a component of an integrated project complexity narrative. This paper investigates how such a project complexity narrative is reflected when informants talk about the role of PM and SE in two academic organizations. Most informants address uncertainty and social-political risks as part of their work, but any consistent use of a project complexity narrative is related to environmental and technical systems. The findings also indicate difficulty differentiating between the concepts of complicated and complex. The paper further contemplates how these findings inform efforts to manage complex research projects and programs.Toward an integrated project complexity narrative – A case study of academic organizationspublishedVersio

    A Systems Engineering Framework for Bioeconomic Transitions in a Sustainable Development Goal Context

    Get PDF
    To address sustainable development goals (SDGs), national and international strategies have been increasingly interested in the bioeconomy. SDGs have been criticized for lacking stakeholder perspectives and agency, and for requiring too little of business. There is also a lack of both systematic and systemic frameworks for the strategic planning of bioeconomy transitions. Using a systems engineering approach, we seek to address this with a process framework to bridge bioeconomy transitions by addressing SDGs. In this methodology paper, we develop a systems archetype mapping framework for sustainable bioeconomy transitions, called MPAST: Mapping Problem Archetypes to Solutions for Transitions. Using this framework with sector-specific stakeholder data facilitates the establishment of the start (problem state) and end (solution state) to understand and analyze sectorial transitions to the bioeconomy. We apply the MPAST framework to the case of a Norwegian agricultural bioeconomy transition, using data from a survey of the Norwegian agricultural sector on transitioning to a bioeconomy. The results of using this framework illustrate how visual mapping methods can be combined as a process, which we then discuss in the context of SDG implementation

    A Systems Engineering Framework for Bioeconomic Transitions in a Sustainable Development Goal Context

    No full text
    To address sustainable development goals (SDGs), national and international strategies have been increasingly interested in the bioeconomy. SDGs have been criticized for lacking stakeholder perspectives and agency, and for requiring too little of business. There is also a lack of both systematic and systemic frameworks for the strategic planning of bioeconomy transitions. Using a systems engineering approach, we seek to address this with a process framework to bridge bioeconomy transitions by addressing SDGs. In this methodology paper, we develop a systems archetype mapping framework for sustainable bioeconomy transitions, called MPAST: Mapping Problem Archetypes to Solutions for Transitions. Using this framework with sector-specific stakeholder data facilitates the establishment of the start (problem state) and end (solution state) to understand and analyze sectorial transitions to the bioeconomy. We apply the MPAST framework to the case of a Norwegian agricultural bioeconomy transition, using data from a survey of the Norwegian agricultural sector on transitioning to a bioeconomy. The results of using this framework illustrate how visual mapping methods can be combined as a process, which we then discuss in the context of SDG implementation

    NZO-3 Expression Causes Global Changes to Actin Cytoskeleton in Madin-Darby Canine Kidney Cells: Linking a Tight Junction Protein to Rho GTPases

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    We previously demonstrated that exogenous expression of a truncated form of the tight junction protein ZO-3 affected junctional complex assembly and function. Current results indicate that this ZO-3 construct influences actin cytoskeleton dynamics more globally. We show that expression of the amino-terminal half of ZO-3 (NZO-3) in Madin-Darby canine kidney cells results in a decreased number of stress fibers and focal adhesions and causes an increased rate of cell migration in a wound healing assay. We also demonstrate that RhoA activity is reduced in NZO-3–expressing cells. We determined that ZO-3 interacts with p120 catenin and AF-6, proteins localized to the junctional complex and implicated in signaling pathways important for cytoskeleton regulation and cell motility. We also provide evidence that NZO-3 interacts directly with the C terminus of ZO-3, and we propose a model where altered interactions between ZO-3 and p120 catenin in NZO-3–expressing cells affect RhoA GTPase activity. This study reveals a potential link between ZO-3 and RhoA-related signaling events

    Toward an integrated project complexity narrative – A case study of academic organizations

    No full text
    The last decade has seen a growing interest in the benefits of applying project management (PM) and system engineering (SE) in an integrated way toward complex projects and programs. The concept of project complexity dimensions, with roots in both disciplines, is suggested as a component of an integrated project complexity narrative. This paper investigates how such a project complexity narrative is reflected when informants talk about the role of PM and SE in two academic organizations. Most informants address uncertainty and social-political risks as part of their work, but any consistent use of a project complexity narrative is related to environmental and technical systems. The findings also indicate difficulty differentiating between the concepts of complicated and complex. The paper further contemplates how these findings inform efforts to manage complex research projects and programs

    Toward an integrated project complexity narrative – A case study of academic organizations

    Get PDF
    The last decade has seen a growing interest in the benefits of applying project management (PM) and system engineering (SE) in an integrated way toward complex projects and programs. The concept of project complexity dimensions, with roots in both disciplines, is suggested as a component of an integrated project complexity narrative. This paper investigates how such a project complexity narrative is reflected when informants talk about the role of PM and SE in two academic organizations. Most informants address uncertainty and social-political risks as part of their work, but any consistent use of a project complexity narrative is related to environmental and technical systems. The findings also indicate difficulty differentiating between the concepts of complicated and complex. The paper further contemplates how these findings inform efforts to manage complex research projects and programs
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