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Covid-19 vaccinations : the unknowns, challenges and hopes
The entire world has been suffering from the coronavirus disease 2019 (COVIDā19)
pandemic since March 11, 2020. More than a year later, the COVIDā19 vaccination
brought hope to control this viral pandemic. Here, we review the unknowns of the
COVIDā19 vaccination, such as its longevity, asymptomatic spread, longāterm side
effects, and its efficacy on immunocompromised patients. In addition, we discuss
challenges associated with the COVIDā19 vaccination, such as the global access and
distribution of vaccine doses, adherence to hygiene guidelines after vaccination, the
emergence of novel severe acute respiratory syndrome coronavirus 2 (SARSāCoVā2)
variants, and vaccine resistance. Despite all these challenges and the fact that the
end of the COVIDā19 pandemic is still unclear, vaccines have brought great hope for
the world, with several reports indicating a significant decline in the risk of
COVID19ārelated infection and hospitalizations.peer-reviewe