Hodgkin lymphoma:hypodense lesions in mediastinal masses

Hypodense volumes (HDV) in mediastinal masses can be visualized in a computed tomography scan in Hodgkin lymphoma. We analyzed staging CT scans of 1178 patients with mediastinal involvement from the EuroNet-PHL-C1 trial and explored correlations of HDV with patient characteristics, mediastinal tumor volume and progression-free survival. HDV occurred in 350 of 1178 patients (29.7%), typically in larger mediastinal volumes. There were different patterns in appearance with single lesions found in 243 patients (69.4%), multiple lesions in 107 patients (30.6%). Well delineated lesions were found in 248 cases (70.1%), diffuse lesions were seen in 102 cases (29.1%). Clinically, B symptoms occurred more often in patients with HDV (47.7% compared to 35.0% without HDV (p = 0.039)) and patients with HDV tended to be in higher risk groups. Inadequate overall early-18F-FDG-PET-response was strongly correlated with the occurrence of hypodense lesions (p &lt; 0.001). Patients with total HDV &gt; 40 ml (n = 80) had a 5 year PFS of 79.6% compared to 89.7% (p = 0.01) in patients with HDV &lt; 40 ml or no HDV. This difference in PFS is not caused by treatment group alone. HDV is a common phenomenon in HL with mediastinal involvement.</p

International Nonregimes: A Research Agenda1

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146934/1/j.1468-2486.2007.00672.x.pd

Walter Hasenclever Collection 1912-1924

This collection contains two letters and their typewritten transcriptions: one letter is written to Elsa Asenijeff in 1912, the other is written to Herr Richter in 1924. The 1912 letter written to Elsa Asenijeff reflects a youthful enthusiastic friendship between the two. The 1924 letter is a business correspondence pertaining to an afterword that Hasenclever contributed to a publication of Swedenborg's "Himmel, Hölle, Geisterwelt".ClippingsGerman writer, born 1890 in Aachen, lived in Dresden and Paris. on 1917 he was presented with the Kleist Prize for his adaption of Sophocles' Antigone. He was imprisoned in a concentration camp in France and commited suicide in 1940.The original German language inventory is available in the folder.Photographs removed to Photograph CollectionProcessed for digitizationSent for digitizationReturned from digitizationLinked to online manifestationdigitize